Problem Solver
Menachem Shoham
Areas Menachem Shoham is Knowledgeable in:
rug discovery and development
identification of drug targets
antibacterial agents
protein structure and function
vasopressin receptor antagonists as drugs against heart disease
identification of drug targets
antibacterial agents
protein structure and function
vasopressin receptor antagonists as drugs against heart disease
Techniques Menachem Shoham Uses:
Drug discovery by virtual screening of very large libraries of small compounds.
In vitro testing of potential anti-virulence compounds.
X-ray crystal structure determination of proteins.
Protein expression, isolation, purification and crystallization
Biophysical techniques
In vitro testing of potential anti-virulence compounds.
X-ray crystal structure determination of proteins.
Protein expression, isolation, purification and crystallization
Biophysical techniques
Menachem Shoham's Problem Solving Skills:
- virtual screening for potential drugs
- in vitro assays for drug efficacy
- protein isolation, purification and crystallization
- crystal structure determination
- proteomics
Menachem Shoham's Problem Solving Experience:
- I discovered a series of anti-virulence compounds active against infections of gram positive bacteria. This invention has been patented. These compounds eliminate the disease, not the bacteria.
- I discovered and patented a natural product active in would healing and against infections of MRSA.