Inventor

Sridhar Mani

-Novel oligonucleotides blocking survivin (an anti-apoptotic protein) for cancer therapy
-Novel hypoxia prodrug for cancer therapy
-Novel drug the blocks microbial b-glucuronidase and thereby used to lessen drugs causing GI TOXICITY (Patent filed in Dec 2010)
-Novel antagonists of orphan nuclear receptor PXR for biological probes and clinical use