Areas Sridhar Mani is Knowledgeable in:
Drug development and target assessments
Medicine and Health (all aspects)
Molecular biology and pharmacology of difficult cellular targets
Techniques Sridhar Mani Uses:
- Theoretical models, structure based designs and creative thinking of new solution in this area
- Experimental design and "out-of-box" models for proof of concept studies in biology
- Wet lab experience to conduct such proof-of-concept experiments and validation
Sridhar Mani's Problem Solving Skills:
- molecular genetics and pahrmacology, clinical medicine and surgery
Sridhar Mani's Problem Solving Experience:
- -I have developed patents in antisense oligonucleotides as therapeutics for cancer
-I have developed toxic drugs that would have failed to FDA approval (clinical)
-I have patents in drug design and discovery for stick problems on protein-protein interfaces
- I have developed a patent on smart drug discovery to subvert clinical drug toxicity