Areas Katherine Sheehan is Knowledgeable in:
Biologics production, pharma, medical device R&D.
Katherine Sheehan's Problem Solving Skills:
- Cost estimation
- Project Management
- Spreadsheet calculations
- Thermodynamics
- Chemical process design
- Heat and mass balance
- Reactor design
- Molecular biology
- Cell culture
- Financial analysis
Katherine Sheehan's Problem Solving Experience:
- I determined the optimum production and operating conditions for prospective new natural gas processing plants to payout capital equipment investment for several potential marketing strategies.
- I designed natural gas processing plants for newly acquired fields including P&ID, generation of computer model data to optimize energy consumption for high-revenue production while meeting regulatory requirements.
- I determined the ionic permeability and blockade of a non-selective cation channel in rat adrenal glomerulosa cells.
- I established that a single regulatory protein affects heart contractility through differential control of interrelated calcium and molecular motor pathways.
- I determined that a novel signaling protein regulates the fidelity of excitation-contraction coupling in cardiac myocytes via differential control of intracellular calcium and membrane excitability,
- I determined the internal molecular mechanism of atrial myocyte excitation-contraction coupling is through step-wise diffusion-mediated activation of internal calcium release units.