Problem Solver
Ken-Shiung Chen
Areas Ken-Shiung Chen is Knowledgeable in:
bacteria engineering, diagnosis of genetic diseases
Techniques Ken-Shiung Chen Uses:
deletion mapping, gene cloning, chromosomal walking, sothern analysis, qPCR, SDS page, vector design, mouse model stem cell modification
Ken-Shiung Chen's Problem Solving Skills:
- genetics
Ken-Shiung Chen's Problem Solving Experience:
- 1. I study the mechanism of recurrent genomic recombination in human genome and developed a method of diagnosis of a genetic disorder.
2. I study the growth of bacteria and figured out that the hungry codon decoded by a rare tRNA restrict the production of proteins dependent on the codon. This finding leads to generation of genetic modified bacteria for improving protein yield using genetic engineering approaches.
3. I generate a mouse with imprinting defect.