Disguised Nanoparticles Provide Immunity to Bacterial Infections

Jan-07-14 A nanoparticle that disguises itself as a red blood cell could lead to a vaccine to fight often-fatal bacterial infections, including infections caused byMRSA.

Liangfang Zhang found that wrapping nanoparticles in the membranes of red blood cells and injecting them into mice infected with a toxin caused the toxin to target the decoy red blood cells and become trapped by the ‘nanosponges,’ which could then be removed from the body and make the bacterial more vulnerable to attacks by the immune system.

Zhang has demonstrated that the same technology could be used to develop vaccines against bacterial toxins by loading the toxin into the nanosponges and injecting them into mice. The nontoxic “nanotoxids” induced antibody production, which provided immunity against the toxin.

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[TECHNOLOGYREVIEW.COM]

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