Gold Nanomesh Reduces Growth of Resistant Bacteria

Oct-17-19 An innovate gold nanomesh drug delivery system could help reduce the spread of bacterial resistance.

The nanomesh, created by a team from Flinders University and the National Institute for Materials Science, is made up of a biodegradable polymer with antibodies and electrically charged gold nanoparticles added to its liquid state. That liquid polymer is then formed into a mesh using an electrospinning technique. In tests, mesh samples placed in petri dishes containing E. coli released their cargo of antibiotics over fourteen days, killing the bacteria. The mesh’s characteristics can also be altered by its charge, with positively charged particles damaging bacteria membranes while negatively charged particles can prolong the release of antibiotics.

According to Professor Ingo Koeper, “Although the dosage is reduced compared to an oral dosage, the concentration of antibiotics delivered to the infection site can still be higher, ensuring the bacteria cannot survive which will reduce instances of resistance.”

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