New Treatment for Knee Injuries

May-17-09 MIT engineers have built a new tissue scaffold that can stimulate bone and cartilage growth when transplanted into knees and other joints, potentially offering a more effective, less expensive – and painful – option to more conventional therapies.

The scaffold developed by MIT has two layers, one that mimics bone and another that mimics cartilage. When implanted into a joint, the scaffold can stimulate mesenchymal stem cells in the bone marrow to produce new bone and cartilage.

The researchers demonstrated the scaffold's effectiveness in a 16-week study involving goats. In the study, the scaffold successfully stimulated bone and cartilage growth after being implanted in the goats' knees. Although the technology is still limited to small defects, using scaffolds roughly 8 mm (0.3-inches) in diameter, the scaffold offers a potential new treatment for sports injuries and other cartilage damage, such as arthritis.

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[GIZMAG.COM]

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