A peptide coating based on human saliva could be applied to teeth to help prevent tooth decay.
The coating features the H5 peptide, which is found in human saliva and creates a film on the teeth that kills bacteria and viruses. The team also boosted the peptide’s performance by adding a phosphoserine group that attracts calcium ions to help repair enamel. In tests, the coating adhered well to the surface of the teeth, preventing biofilms and the loss of enamel.
The team believes the peptide coating could eventually be applied to teeth after brushing to offer extended anti-cavity protection.