Ultrasound Drives Medication in the Brain

Ultrasound Drives Medication in the Brain
A combination of ultrasound and nasal spray could help medication pass through the blood-brain barrier to target and treat brain tumors.

The method, from Washington University, combines the established procedure of drug delivery via an intranasal spray with focused ultrasound pulses to drive the medication to a targeted area in the brain. After the medication is inhaled via the nasal spray, microbubbles are injected into the bloodstream (this can be on the arm) while an ultrasound wave is applied to the brain region to be treated. The ultrasound causes the bubbles to oscillate as they move through the target region, triggering the blood vessels to expand and contract and draw the medication to the tumor and out of the perivascular space that usually prevents medication transference.

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