Method for the Solid Phase-based Production of Phosphate-bridged Nucleoside Conjugates
The invention relates to a method for producing phosphate-bridged nucleoside conjugates. In the method, a cyclosaligenyl nucleotide is produced first, to which a linker is added, which is used to perform the immobilization on a solid phase. A subsequent reaction with corresponding nucleophiles results in the desired phosphate-bridged nucleoside conjugates, which can then again be cleaved from the solid phase-bound linker.
Attached files:Patents:WO 2,010,127,666
Inventor(s):
MEIER CHRIS [DE]; TONN VIKTORIA [DE]
Type of Offer:
Sale
« More Chemistry Patents