Parathyroid Hormone Treatment for Enhanced Allograft and Tissue-engineered Reconstruction of Bone Defects

Methods of improving an outcome of a bone allograft procedure in a subject suffering from a massive bone defect are described, including providing a bone allograft to the subject and intermittently providing said subject with parathyroid hormone (PTH); where the PTH is provided in an amount effective to enhance in or adjacent to a bone allograft, relative to a patient not provided the PTH, at least one of callus bone volume, callus mineral content, callus bridging, graft stiffness, graft incorporation, and graft resistance to an applied torque.

Patents:
US 20,090,227,503

Inventor(s): AWAD HANI A [US]; SCHWARZ EDWARD M [US]; BUKATA SUSAN [US]; PUZAS J EDWARD [US]; O'KEEFE REGIS J [US]; ROSIER RANDY [US]

Type of Offer: Licensing



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