MCK Cre Mice
Description: This technology is an improvement to the cre-lox system for making targeted gene knockouts in mice. Clinical & Commercial Utility: The available technology features a line of mice harboring the Cre DNA recominbase gene under the control of the muscle creatine kinase promoter. These mice can be used to create muscle-specific knockouts using the cre-lox system. Patent Status: The creation of this mouse line, and a description of its use, are published in Bruning et al. (1998) Mol. Cell. 2: 559-569.Type of Offer: Licensing
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