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Healthcare

The following are Healthcare technologies offered for sale or license. Viewing technologies for sale is a free service of IdeaConnection.com, as is connecting with the seller if a technology interests you. Click on a heading below for more information.

Healthcare pertains to anything that relates to the physical or emotional well-being of the human species. Healthcare encompases preventative measures as well as solutions, that help relieve the symptoms of disease. Post your healthcare technologies for sale or license.


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Methods and apparatus for determining body weight and fat content using computed tomography data

Methods and apparatus for determining body weight and fat content using computed tomography data are provided. One method (60) includes acquiring (62) a pre-scan image using a computed tomography imag..

DEVICE FOR OSTEOSYNTHESIS

The aim of the invention is to provide an osteosynthesis plate (100) or a kit for osteosynthesis that clearly reduces the risks associated with the treatment of a bone fracture using the osteosynthesi..

BIOEQUIVALENCE DIALYSIS

The present invention relates to a method for treating blood disorders and blood disorders compensation. This includes steps in which one blood or blood plasma of a patient outside the body brings wit..

MAGNETICALLY MOUNTED ARTIFICIAL JOINT

The invention relates to a prosthesis for replacing a joint compound in the same magnetic fields of joint head 10, socket 12 and pivot collar 14 can be superimposed so that the repulsive forces produc..

METHOD FOR DETERMINING THE CLAMPING FORCE ON A MECHANICAL JOINT CONNECTION CONNECTING AT LEAST TWO COMPONENTS

The invention relates to a method for determining the clamping force on a mechanical joint connection connecting at least two components by coupling sound waves into the joint connection. The inventio..

PRECURSORS OF LIPID METABOLISM FOR THE DIAGNOSIS AND TREATMENT OF CANCER

The present invention pertains to methods for the treatment and diagnosis of cancer employing prodrugs for targeting of lipid metabolism comprising either a detectable label or a therapeutic residue. ..

PREVENNTING THE OCCURRENCE OF OBESITY

Administration of autophagy inhibitor (e.g. 400 mg chloroquine daily) prevents occurrence of obesity and insulin resistance in human subject on prolonged high-fat diet.

METHOD FOR TREATING OBESITY

The present invention relates, in general, to obesity, and, in particular, to a method of treating obesity and minimizing metabolic risk factors associated therewith using, for example, zonisamide or ..

Human and physical asset movement pattern analyzer

A system of tracking and analyzing the movement of human subjects. UWB is used to track the location of all persons and/or physical objects (assets) occupying a defined area, giving their location wit..

FOLDING ARMREST TRAY FOR WHEELCHAIRS

A tray assembly mounted on a wheelchair. A housing containing the tray is mounted along the side of the chair arm. The tray assembly has a tray surface moveable between a stowed and unstowed position...

PHARMACEUTICAL COMPOUNDS COMPRISING ABASIC OLIGONUCLEOTIDES

The present invention relates to compounds which are capable of modulating Toll-like receptor (TLR) activity.

PYRIMIDINIUM DERIVATIVES FOR USE IN THE TREATMENT OR PREVENTION OF DIABETES

The present invention relates to methods and compositions for preventing or treating diabetes. The invention in particular discloses compounds according to formula (I) for use in the prevention and tr..

N-TERMINALLY MODIFIED TETRAPEPTIDE DERIVATIVES HAVING A C-TERMINAL ARGININE MIMETIC

The invention relates to multi-base, N-terminally modified tetrapeptide mimetics having a C-terminal P1 arginine mimetic, to a method for producing the same and to the use thereof in the therapy and p..

USE OF HAT INHIBITORS AND TMPRSS2 INHIBITORS AS MEDICAMENTS

The invention relates to the use of inhibitors of the general formula (I) where R1 is a substituent, P3 is a mono- or polysubstituted or unsubstituted, natural or unnatural a-amino acid or a-imino aci..

MONOCLONAL ANTIBODIES AGAINST CLAUDIN-18 FOR TREATMENT OF CANCER

The present invention provides antibodies useful as therapeutics for treating and/or preventing diseases associated with cells expressing CLDl 8, including tumor-related diseases such as gastric cance..

USE OF RNA FOR REPROGRAMMING SOMATIC CELLS

The present invention provides methods for de-differentiating somatic cells into stem-like cells without generating embryos or fetuses. More specifically,-the present invention provides methods for ef..

ANTIBODIES SPECIFIC FOR CLAUDIN 6 (CLDN6)

The present invention provides antibodies useful as therapeutics for treating and/or preventing diseases associated with cells expressing Claudin-6 (CLDN6), including tumor-related diseases such as ov..

DIETARY COMPOSITIONS AND RELATED METHODS OF USE

The present invention provides dietary compositions for mammalian consumption. In particular, the present invention provides compositions comprising pectin, a component comprising electrolytes, thicke..

METHOD FOR DETECTING THE EXISTENCE OF RENAL CALCULI AND/OR INFLAMMATION OF THE EXCRETORY URINARY TRACTS

The invention relates to methods for detecting diseases of the excretory urinary tracts. The aim of the invention is to provide a method for detecting the existence of diseases of the excretory urinar..

MARKING CLIP FOR AN AREA OF THE INSIDE WALL OF THE STOMACH OR INTESTINE

The invention relates to marking clips for an area of the inside wall of the stomach or intestine. These are characterized in particular by the fact that damaged or treated areas of the inside wall of..

METHOD FOR DETECTING THE EXISTENCE OF RENAL CALCULI AND/OR INFLAMMATION OF THE EXCRETORY URINARY TRACTS

The invention relates to methods for detecting diseases of the excretory urinary tracts. The aim of the invention is to provide a method for detecting the existence of diseases of the excretory urinar..

X-RAY MARKER FOR VISUALLY COMPARING AND FOR CONTROLLING THE IMAGE PROCESSING IN DIGITAL X-RAY RECORDINGS, IN PARTICULAR FOR A THORAX X-RAY RECORDING FOR A PATIENT LYING DOWN

The invention relates to an X-ray marker (1) that is also to be X-rayed in an X-ray recording of an organ of a patient (3) to be examined. The X-ray marker (1) has such a geometric X-ray weakening str..

DEVICE FOR DETERMINING VERTEBRAL DISTANCES OF THE SPINAL COLUMN OF A PATIENT

The invention relates to devices for determining vertebral distances of the spinal column of a patient. The devices are characterized in particular in that vertebral distances of the patient while wal..

BIOLOGICALLY ACTIVE MOLECULES, PARTICULARLY BASED ON PNA AND SIRNA, METHOD FOR THE CELL-SPECIFIC ACTIVATION THEREOF, AND APPLICATION KIT TO BE ADMINISTERED

Biologically active molecules are inactivated for selective activation by target cells by being covalently bonded to one or more peptides each of which has one or more specific amino acid sequences th..

STIMULATION OF CPT-1 AS MEANS TO REDUCE WEIGHT

PROBLEM TO BE SOLVED: To provide a method and composition for inducing weight loss and maintaining optimum weight. ; SOLUTION: An agent is administered that stimulates carnitine palmitoyl transferase-..

SKIN AND SURFACE DISINFECTANT COMPOSITIONS CONTAINING BOTANICALS

The present invention relates to a skin or surface disinfectant composition with broad spectrum antimicrobial activity comprising one or more essential oil (and/or one or more component thereof) and o..

PROLONGED EFFECT DISINFECTANT CLEANSER.

The present invention relates to cleanser compositions, and their uses, wherein the cleanser compositions comprise one or more cationic antiseptic agents, a film-forming cationic emulsifying agent, a ..

OBESITY CONTROLLING METHOD

A method of controlling obesity by injecting bio-compatible bulking material into the pyloric sphincter area of the stomach. The injection of this material bulks the pyloric sphincter, retarding stoma..

REAL-TIME X-RAY VISION FOR HEALTHCARE SIMULATION

A medical procedure training system and method for using is provided. The system includes a sensing system structured to detect the position and motion of a medical device inserted into a simulated bo..

METHOD FOR STRUCTURAL HEALTH MONITORING USING A SMART SENSOR SYSTEM

The structural health monitoring method of the present invention utilizes a sensor system to determine information about deformation, stress and/or damage in structural elements. The sensor system and..

NATURAL POLYPEPTIDES FOR ORAL HEALTH CARE.

Tlic present invention relates generally to dental diseases, caries and periodontal disease. More specifically, the invention relates to Lactoferrin and Stathcrin fusion proteins (STAT-LF) along with ..

A MULTIPLE DEGREE OF FREEDOM REHABILITATION SYSTEM HAVING A SMART FLUID-BASED, MULTI-MODE ACTUATOR

A rehabilitation system that combines robotics and interactive gaming to facilitate performance of task- specific, repetitive, upper extremity/hand motor tasks, to enable individuals undergoing rehabi..

LYSINE-SPECIFIC DEMETHYLASE 1 (LSD1) IS A BIOMARKER FOR BREAST CANCER

The present invention relates to novel biomarker for breast cancer, namely LSD1 and its application in inter alia the diagnosis of breast cancer. Furthermore, the present invention discloses a method ..

METHOD FOR OBTAINING HUMAN MICROGLIAL PRECURSOR CELLS FROM PLURIPOTENT STEM CELLS

The present invention relates to a method for obtaining human microglial precursor cells, comprising: (a) providing a ceil population comprising neural precursor cells, wherein the cell population is ..

ANTICANCER AGENT

The present invention relates to a pharmaceutical composition for the therapeutic and/or prophylactic treatment of cancer and/or metastasis thereof comprising an amino acid sequence related to a Wech ..

APPARATUS AND METHOD FOR DETECTING TRIACETONE TRIPEROXIDE

The present invention relates to an apparatus and method for fast and secure online detection of triacetone (TATP).

INHIBITORS OF THE NITRATION OF AMYLOID ss PEPTIDES AND THEIR USES IN THE DIAGNOSIS AND TREATMENT OF ALZHEIMER'S DISEASE

The present invention relates to a method for identifying an inhibitor of the aggregation of amyloid-ss peptide (Ass), comprising the steps of a) contacting at least one Ass-peptide and/or the nitrate..

CYTOHESIN INHIBITORS

The present invention relates to a pharmaceutical preparation comprising as an active ingredient a primary amide according to the general formula (1) and/or a secondary amide according to the general ..

METHOD AND DEVICE FOR GRAVITY LIKE SIMULATION OF NATURAL BALANCE MOVEMENTS

We present a tool that can enhance the concept of BWS training by allowing natural APAs to occur mediolaterally. While in a supine position in a 90 degree tilted environment built around a modified ho..

CROSS-LINKED BIOPOLYMERS, RELATED COMPOSITIONS AND METHODS OF USE

The present invention provides stabilized oil-in-water emulsions with an extended range of chemical, thermal and/or mechanical stabilities, and method(s) for their preparation. Such preparations provi..

PORTABLE DEVICE AND METHOD FOR MEASUREMENT AND CALCULATION OF DYNAMIC PARAMETERS OF PEDESTRIAN LOCOMOTION

The invention relates to a portable and autonomous device and corresponding method for the measurement, recording and calculation of dynamic parameters of the pedestrian locomotion of its bearer (1). ..

PROTEINS THAT STIMULATE THE SECRETION OF SATIETY HORMONES

The invention is in the field of weight management, in particular in the field of weight management by influencing the mechanisms of body-weight regulation. Intact pea protein and intact wheat protein..

A PROSTHESIS OR ORTHOSIS

A prosthesis or orthosis comprising a first body and a second body rotatable to one another, comprising a passive mechanical converting mechanism comprising a third body arranged movably with respect ..

INHIBITORS OF ANOREXIC LIPID HYDROLYSIS FOR THE TREATMENT OF EATING DISORDERS

Compounds, pharmaceuticals, cosmetic or dietary supplements for the treatment of overweight, obesity and/or type II diabetes in a mammal (e.g. human) comprising a compound with formula I or formula II..

A walking aid with a means for effectively varying its length during use

A walking aid 10 having a means for varying its length being configured to maintain a substantially constant vertically resolved distance between the user and the ground when the aid is tilted from a ..

BENZENE DERIVATIVES

Compounds with the general formula (I): are described wherein R1, R2, R3, R4, R5, Q, T, X, Y and Z are as defined. Compounds according to the invention can display potent inhibition against Hepatitis ..

TREATMENT OF CACHEXIA.

The invention characterises and provides a receptor for Proteolysis Inducing Factor (PIF) and associated methods and materials employing the same. These have utility, for example, in the provision of ..

SMALL MOLECULE INTERVENTION FOR OBESITY.

Methods and compositions for activating PLTP gene expression include administering an effective amount of a limonoid.

TRUNK ROTATION

This trunk rotation device uses dynamic movement of one's body such as, shoulder, hip, knee, back, thigh, and abdominal musculature. The device provides a method for exercising the spinal column and t..

Wireless apparatus with proximity sensor switches allowing a disabled person to control an electronic device.

Disclosed is a proximity sensor switch operated control unit for electronic devices to be used by disabled persons with limited motor skills. The control unit consists of switches that sends signals t..

Male Contraceptive

A compound having formula I. R1, R2, R3 and R4 are independently H or lower alkyl. R5 is aryl, heteroaryl, cycloalkyl, heterocycloalkyl, aryloxy, heteroaryloxy, cycloalkyloxy, heterocycloalkyloxy, ary..

METHOD OF STRATIFYING BREAST CANCER PATIENTS BASED ON GENE EXPRESSION

The present invention assists in prospectively predicting the metastatic likelihood, and thereby, the likely clinical outcome of breast cancer patients, based on the genotype of the patient, in partic..

Copolymer for use in corneal bandages

A copolymer for use in corneal bandages comprises of units -(A)- and -(B)- in which the units A are derived from aminoalkyl (alkyl)acrylates, such as 2-(diethylamino)ethyl methacrylate (DEAEMA), 2-(di..

HYDRATING COMPOSITION

The present invention relates to methods and compositions for enhancing the ability of the body to absorb ingested water and retain water in the tissues. Compositions and methods of the invention may ..

ASSESSMENT OF FUNCTIONAL STATUS

This invention relates to methods of neurocognitive assessment and, in particular, to methods for assessing the ability of individuals, in particular, memory- impaired individuals, to perform daily ac..

Closed loop diabetes management system

Diabetes management apparatus comprising a sensor 12 providing measurements of glucose level in a human or animal; an insulin pump 16 for delivering a dose of insulin to said human or animal; and a pr..

OVERNIGHT CLOSED-LOOP INSULIN DELIVERY WITH MODEL PREDICTIVE CONTROL AND GLUCOSE MEASUREMENT ERROR MODEL

A closed-loop system for insulin infusion overnight uses a model predictive control algorithm ("MPC"). Used with the MPC is a glucose measurement error model which was derived from actual glucose sens..

Transport device for attachment to a wheelchair or similar

A transport device, an in particular sliding assistance or a stair riser to the cultivation at a wheelchair or such a thing, comprehensively a grasp device (2), a drive device (3) and a liaison vehicl..

A Novel Method for the Treatment of Obesity

Isis Project No 3593 Isis Innovation, the technology transfer arm of the University of Oxford, releases a new causal-link, with potential in the treatment of obesity. Cysteine levels have been shown t..

Onion preparation

Onion phenolics and flavonoids are types of phytochemicals, which are antioxidant chemicals that protect plants against bacteria, viruses and fungi. Phenolics and flavonoids, like other antioxidants, ..

Low Level Laser battery operated medical devise

Medical Device: A low level hand held battery operated medical laser device has been developed and clinically tried with proven good results on almost all medical conditions encountered in a medica..

NOVEL SIMPLE ORGANIC COMPOUNDS FOR TREATING OBESITY

Highlights Novel small organic compounds derived from fatty acids , for treating obesity by regulating feeding and body weight Experiments in mice showed decreased food consumption and increased a..

Marine natural products as active anti-cancer agents

Marine natural products have gained increasing importance as a source of potential anticancer agents in the last few decades. Drs. C Ireland and L Barrows are exploring the possibilities to identify n..

Lower Extremity Feedback System; In-Shoe Sensors; Incline & Step Counts

Today an inactive lifestyle is seen in children as well as adults. Lack of physical activity affects early onset diabetes, obesity, heart disease, and other chronic illnesses. These illnesses have a n..

Protein Kinase C-d in combination therapy with Bortezomib

Bortezomib is a targeted cancer drug which acts by blocking proteasomes, clusters of proteins necessary for tumor cell growth. It induces mitochondrial damage in cancer cells. Dr.Ray Lee and co-resear..

"To Thirty and Beyond" a Ventilator Associated Pneumonia Prevention CD-Rom

This is a 20 minute educational CD-Rom designed to teach physicians, respiratory therapists, and nurses, how to overcome barriers to maintaining the head of the bed at an angle of thirty degrees or hi..

System for Providing Emergency Medical Care with Real-Time Instructions and Associated Methods

This disclosure describes the Basic Life Support System (BLSS) and a just-in-time training procedure for a first responder who must administer cardio pulmonary resuscitation (CPR). Just-in-time suppor..

Melatonin System for Regulating Immune Response Following Trauma (e.g., Injury, Stress, Transplantation)

This invention is a method of stimulating post-trauma immune response in warm-blooded animals, including humans. This method employs exogenous melatonin to moderate cytokine production in response to..

Bioluminescence Based Lab-on-a-Disc

Due to the rising cost of health care, hospitals have been driven to reduce the amount of diagnostic tests being performed, compromising patient treatment. In addition, central chemistry labs are oft..

Wheelchair Advantage Mobility System (WAMS)

WAMS is a bolt-on system with hand-actuated levers and disc/caliper system to propel, brake and securely park a manual wheelchair. It incorporates a set of ergonomic handles that enables users with r..

Navigational System for Persons with Varying Physical Disabilities

This technology is a Web-based navigational tool to assist people of varying physical ability levels in identifying shortest feasible routes through urban environments. There are several limiting fac..

Physician Time Tracking System

This system consists of a central database accessible through web interface for tracking information required by the Accreditation Council of Graduate Medical Education (ACGME) for resident physicians..

A Dual Catheter System for Confocal Imaging of Cardiac Microstructure for Diagnosis of Diseases and Evaluation of Therapeutic Interventions


Database and Knowledge-base Enhancements

Healthcare costs continue to escalate at a steep rate. Cost increases have occurred in all areas, including insurance premiums, medical equipment, medicines and costs for visits to doctors. A great de..

Instrumented Model of the Human Torso for Ballistic Impact

Effective body armor minimizes injury by transferring the kinetic energy of a projectile over an extended time-scale or surface area. Body armor that accomplishes such energy transfer using lightweigh..

Wheelchair Toileting Module and Method

The invention provides for a toileting module which can be used in a standard wheelchair and consists of straps and a tensioning mechanism therefor attached to a support structure. The straps run unde..

Apoptosis and Self-destruct: Mechanisms For Management Of Autonomic Systems (GSC-14968)

Abstract: Autonomic Computing is an emerging area for research and practice that is being promoted by IBM and others. The idea is to borrow principles from the human autonomic system and apply them t..

Resistive Exercise Equipment (MSC-23196)

Abstract: While NASA scientists created the technology to offset the adverse effects of long-term microgravity exposure, including muscle atrophy and loss of bone mineral density, the devices are ada..

Rehydration Beverage ()

Abstract: This novel rehydration beverage contains sodium chloride, sodium citrate and aspartame useful for rapid restoration of hydration homeostasis. The beverage is particularly useful for restora..

A Method of Operation for the Quadrupole Ion Trap in the Resonance Ejection Mode with Linear Dependence of the mlz Ratio of Ejected Ions upon the Trapping RF Voltage

A method for producing precise linear mass calibration and accurate mass measurements in the resonance ejection mode of an ion trap mass spectrometer using modulation of the endcap voltage amplitude p..

Device and Method for Measuring Spinal Reposition Sense (20013)

Proprioception is used by the body to communicate position sense and appreciation of movement of body parts. Receptors located in muscles, ligaments, tendons, capsules, menisci and the skin provide pr..

Automated Alignment System for Prosthetic Feet (20030)

Different types of prosthetic feet necessitate different alignment. Dynamic Alignment of prosthetic feet is currently accomplished using empirical, iterative methods. A clinician tentatively aligns th..

Method and Apparatus for Measuring Limb Position Sense During Cyclic Limb Movement (20086)

INVENTION: Limb position sense (LPS) is the ability of a subject to detect the position of his/her arm or leg in space. During locomotion, limb position sense is regulated by sensory feedback to the n..

Marionet (26033)

INVENTION: MARIONET is a “robotic assist” device for home use in rehabilitation. Unlike currently available robotic-assist devices, MARIONET is: Small & lightweight Inexpensive Safe & compli..

NUberwalker

INVENTION: The NUberwalker is a 2006 winner of the Davinci award that “honors outstanding engineering achievements relative to design process, product design and applied research related to accessib..

Adaptable Ankle-Foot Prosthesis

INVENTION: The Adaptable Ankle-Foot Prosthesis automatically adapts to different surface slopes and to shoes of different heel heights. Current prosthetic ankle-foot mechanisms cannot automatically ad..

The Write Away

INVENTION: The Write Away is an easy-to-use writing aid for individuals with physical impairment such as arthritis or stroke. Unlike currently available writing aids, The Write Away: Is easy to gr..

Prosthetic Foot with Adjustable Flat Region

INVENTION: The invention is a prosthetic foot that presents a flat region for standing but that has flexibility for walking. The foot can assume a stable position during standing and a "rollover shape..

Bi-Modal Prosthetic Foot

INVENTION: The Bi-Modal Prosthetic Foot presents a flat foot during standing and a flexible foot during walking. It can assume a stable position during standing and a "rollover shape" during walking. ..

SMART Reimbursement and Contract Modeling Tool

The software application includes a web interface which allows users to define the expected (health insurance) reimbursement rate for an unlimited number of commercial third party payers (e.g. Blue Cr..

Methods and Protein Biomarkers Predictive of Toxic Exposure, Health Status and Disease

The present work describes a list of novel and specific biomarker targets and a novel data analysis strategy for determining current health status, the occurrence of past exposures to toxic chemicals,..

Mechanism for Input, Transmission, and Analysis Mechanism of Self-assessed Pain Level for Patient Monitoring and Diagnostics

a. The device offers a novel method of monitoring pain in patients. The design allows doctors/nurses to track the pain levels felt by the patient much like heart rate and other metrics are currently v..

Hospital at Home Care Model

Acute hospital care can be burdensome for elderly patients. Providing acute hospital-level care to a patient in his home in lieu of an acute hospital admission may improve patient outcomes and be les..

Web-Based Diabetes Data Management Application

Intensive control of blood glucose levels may delay the onset and progression of microvascular complications that contribute to the morbidity and mortality of patients with type 1 and type 2 diabetes..

Improved Production of Clavulanic Acid by Genetic Engineering of Streptomyces Clavuligerus

Clavulanic acid is a potent beta-lactamase inhibitor used to combat resistance to penicillin and cephalosporin antibiotics. There is a demand for high-yielding fermentation strains for industrial prod..

Johns Hopkins Diabetes Management Program

The invention encompasses a team of health care professionals who directly manage the pharacologic, nutritional and educational components of the medical care plan for hospitalized patients with diabe..

Removing Insult from Injury: Disclosing Adverse Events

Abstract (Set) Researchers at Johns Hopkins developed 25-minute training video, Removing Insult from Injury: Disclosing Adverse Events that helps to educate physicians and hospitals in how to disclos..

Wild-Type Amyloid Precursor Protein Yeast Artificial Chromosome Transgenic Line Py8.9

Researchers at Johns Hopkins and Case Western Reserve University have generated a transgenic mouse (Py8.9) line that expresses the wild-type human Amyloid Precursor Protein (APP). This mouse was gene..

Hand Held Patient Tracking, Education and Decision Support (TEDS) Tool

This product is a computerized handheld decision support device that would be used by a physician-led team od Community Health Workers working in the field to constantly monitor AND address patient he..

Web-based Heparin Management System

Thrombotic disorders (myocardial infarction, unstable angina, stroke, deep venous thrombosis, pulmonary embolism) are among the most common reasons for hospital admission. (1) Anticoagulation plays an..

High Resolution Three-dimensional (3D) Iterative Pinhole Image Reconstruction Methods

The invention is a three-dimensional (3D) iterative pinhole image reconstruction method and its software implementation for use in high-resolution pinhole SPECT imaging. The method and software is par..

IHC Software

A comprehensive software program has been developed to aid in immunohistochemical laboratory studies. At present, no such comprehensive and integrated software program with equal or similar capabilit..

The JHU Sleep Center's Interactive Training Module for Polysomnogram (PSG) Scoring

Abstract (Set) This interative computer program represents the first fully interactive tool that allows one to score sleep studies that can be checked against board certified and eligible sleep speci..

Home Link System for Daily Monitoring of Outpatients

Despite landmark basic and clinical research advances in our understanding of the pathophysiology and treatment of CHF, the majority of patients are not receiving or applying optimal pharmacologic the..

Method to Assess Vascular Endothelial Function using Phase-Contrast Magnetic Resonance Angiography

Endothelial function is crucial in maintaining cardiovascular health. FMD is a noninvasive method of evaluating endothelial function. Impaired FMD measured by ultrasound correlates with cardiovascular..

Method for Measuring Myocardial Motion

A method of magnetic resonance imaging of myocardial motion includes positioning a portion of a patient such as a patient's heart within a main magnetic field and employing a plurality of RF signals t..

A Dipole Antenna for Magnetic Resonance Imaging and Spectroscopy

The invention provides a method for magnetic resonance imaging and spectroscopic analysis of a specimen which includes positioning the specimen within a main magnetic field and introducing an antenna ..

Sickness Impact Profile" a/k/a "SIP (Copyright Only)

Sickness Impact Profile (SIP) is an assessment tool that consists of 136 questions and measures behaviorally-based health status. It has been validated and used for over 30 years. The SIP can be self-..

Child Health & Illness Profile - Child Edition (CHIP-CE), Child Report Form & Parent Report Form

The Child Health and Illness Profile (CHIP) is a family of self-report questionnaires designed to assess the health of children (Child Edition-CE) and adolescents (Adolescent Edition-AE) ages 6 throug..

Screening instrument (PraPlus)

Pra and PraPlus are screening tools that identify elders who are at high risk for using healthcare services heavily in the future. Pra is 8-item questionnaire and PraPlus has additional 9 items that e..

Skills Trainer for Robotic Surgery

Robotic surgery is becoming increasingly popular with the advent of robotic technology in medicine. With this, there arises a need to extensively train the surgeons to effectively use these devices. S..

Composition of Liposomal GM-CSF

Pharmaceutical and immunological scientists at the University at Buffalo have developed novel formulations for cytokine and growth factor drugs, including recombinant interleukin-12 (rhIL-12), GM-CSF ..

CPAP titration using artificial neural network

For 18 million Americans suffering from Obstructive Sleep Apnea (OSA) this is as frustrating as a dog chasing its tail. Lack of proper sleep can lead to severe health problems and increased risk of ac..

Method for Inhibiting Proteases in the Oral Cavity

Sensitive teeth, a condition which affects more than 45 million Americans each year, likely results from exposed dentinal tubules. A number of products have been developed that either occlude the expo..

Composition and method of preparation of liposomal microparticulate IL-12 for immunotherapy

Pharmaceutical and immunological scientists at the University at Buffalo have developed novel formulations for cytokine and growth factor drugs, including recombinant interleukin-12 (rhIL-12), GM-CSF ..

CryoTissue Conditioner (Conditioner Solution for Frozen Tissue Sections for Histological Examination)

Microscopic examination of tissue morphology and intracellular protein content is one of the major methods of assessing disease states in tissue samples. Current techniques often result in damage to t..

Intestinal Coupling Device

Esophageal atresia with tracheal esophageal fitula occurs in approximately 1 in 1500-5000 newborns. This is a congenital defect in which the esophagus does not form a continuous connection to the stom..

Esophageal Coupling Rings

Esophageal atresia with tracheal esophageal fitula occurs in approximately 1 in 1500-5000 newborns. This is a congenital defect in which the esophagus does not form a continuous connection to the stom..

Esophageal Coupling Device

Esophageal atresia with tracheal esophageal fitula occurs in approximately 1 in 1500-5000 newborns. This is a congenital defect in which the esophagus does not form a continuous connection to the stom..

Composition of the reconstitution medium for protein and peptide formulations

Pharmaceutical scientists at the University at Buffalo have developed a rational strategy to design compositions for the reconstitution of freeze-dried protein/peptide formulations. These compositions..

MUC7 20-mer Peptide: Novel and Promising Antifungal and Antibacterial Therapeutic Agent

This invention encompasses peptide derivatives of a naturally occurring protein found within the human body. These peptides have been shown to posses potent antifungal and antibacterial activity compa..

A Method to Distinguish Organisms Causing Exacerbations of Chronic Bronchitis

The invention provides a simple, quick and inexpensive test for discriminating between bacterial and non-bacterial exacerbations of chronic lung disease. The test is based on the strong correlation be..

CryoTissue Conditioner (Conditioner Solution for Frozen Tissue Sections for Histological Examination)

Microscopic examination of tissue morphology and intracellular protein content is one of the major methods of assessing disease states in tissue samples. Current techniques often result in damage to t..

A Method to Distinguish Organisms Causing Exacerbations of Chronic Bronchitis

The invention provides a simple, quick and inexpensive test for discriminating between bacterial and non-bacterial exacerbations of chronic lung disease. The test is based on the strong correlation be..

Skills Trainer for Robotic Surgery

Robotic surgery is becoming increasingly popular with the advent of robotic technology in medicine. With this, there arises a need to extensively train the surgeons to effectively use these devices. S..

CPAP titration using artificial neural network

For 18 million Americans suffering from Obstructive Sleep Apnea (OSA) this is as frustrating as a dog chasing its tail. Lack of proper sleep can lead to severe health problems and increased risk of ac..

Intestinal Coupling Device

Esophageal atresia with tracheal esophageal fitula occurs in approximately 1 in 1500-5000 newborns. This is a congenital defect in which the esophagus does not form a continuous connection to the stom..

Esophageal Coupling Rings

Esophageal atresia with tracheal esophageal fitula occurs in approximately 1 in 1500-5000 newborns. This is a congenital defect in which the esophagus does not form a continuous connection to the stom..

Esophageal Coupling Device

Esophageal atresia with tracheal esophageal fitula occurs in approximately 1 in 1500-5000 newborns. This is a congenital defect in which the esophagus does not form a continuous connection to the stom..

Composition of Liposomal GM-CSF

Pharmaceutical and immunological scientists at the University at Buffalo have developed novel formulations for cytokine and growth factor drugs, including recombinant interleukin-12 (rhIL-12), GM-CSF ..

Composition and method of preparation of liposomal microparticulate IL-12 for immunotherapy

Pharmaceutical and immunological scientists at the University at Buffalo have developed novel formulations for cytokine and growth factor drugs, including recombinant interleukin-12 (rhIL-12), GM-CSF ..

Composition of the reconstitution medium for protein and peptide formulations

Pharmaceutical scientists at the University at Buffalo have developed a rational strategy to design compositions for the reconstitution of freeze-dried protein/peptide formulations. These compositions..

Biomarkers for Cardiovascular Disease

Introduction Cardiovascular disease (CVD) is the leading cause of death among both men and women in the United States and, as such, is associated with high costs in terms of health care, morbidity, an..

Calcipressins: Lead Targets for Autoimmune, Inflammatory, and Cardiovascular Disease

Summary The development of more selective immunosuppressive agents to mitigate transplant rejection and autoimmune diseases requires effective strategies of blocking signaling pathways in T cells. Cur..

Efficient Air Purification and Lighting

Introduction According to the CDC, one third of the world’s population is infected with tuberculosis (TB) with nearly 9 million newly infected and nearly 2 million related deaths each year. This re..

Wearable Low Vision Aids Using Retinal Light Scanning Technologies

Introduction Severe visual impairment (those persons classified as legally blind) affects over 1 million Americans currently. With the aging of the U.S. population, this visually impaired segment is e..

Optimal Fitting of Prosthetic Limbs: Evaluation of Prosthetic Socket Quality and Soft-Tissue Response

Introduction The process of fitting prosthetic limbs to amputees can be a long process of trial and error. Two common obstacles to the optimal fitting of prosthetic limbs are improperly tooled prosthe..

SirT1 Conditional Knockout Mice

Introduction SirT1 is a nicotinamide adenine dinucleotide (NAD)-dependent deacetylase capable of modifying the activity of many transcription factors that have been implicated in the physiology and pa..

Fluorescent Microglial Cell Lines

Introduction Microglial cells are the resident immune cells of the central nervous system. Upon brain damage, these cells are rapidly activated and transform from a resting state into activated microg..

Automated laboratory system and analytical module

Our invention: Fast Lab Technology is a cornerstone in preventive and lower cost health care of USA Government program: http://www.codebuildingblocks.com/Michael/FastSpin Our technology intends to..

Piezoelectric Structural Health Monitoring Systems

Introduction All engineered works suffer the damages of time, intended use, and disaster. Skyscrapers, bridges, dams, aircraft, and freight trucks are just a few examples of constructs where structura..

Circulating Fluidized Beds for Continuous Protein Refolding

This technology enables the continuous handling of heterologous inclusion proteins, minimizing the attrition often seen from repeated batch handling. Description Background Many recombinant ex..

High Efficiency Photocatalytic Reactor for Water Treatment: PhotoCREC Water

Device that utilizes a titanium dioxide catalyst supported on a solid media to enhance the natural activity of UV light to destroy the toxic organic contaminants in water

Haptic Feedback System for Minimally Invasive Robotic Surgery

A novel Minimally Invasive Surgery (MIS) robotic system that successfully incorporates haptic feedback control. Description Background Minimally Invasive Surgery (MIS) was established as a..

Agricultural De-Nitrification Reactor for Contaminated Run-Off

A passive reactor system for the containment and treatment of nitrate contaminated agricultural runoff - or an “Agricultural Basket”. Description The common agricultural practice of o..

Apparatus and Method for Cell Culture

A method for controlling the properties of the microenvironment surrounding a single cell in a cell culture. Background Typically, cells are cultured in vitro by growing cells in a fluid or gel-..

DIABETES FOOD ADDITIVE, NEUTRACEUTICAL & DRUG

Project 1: We currently are marketing / outlicensing a diabetic food additive / neutraceutical. Possible Drug development aspects. Project 2: We are looking for a grant, an angel investor(s) and..

Process for the treatment of pig manure

Agriculture and Agri-Food Canada is offering a commercialization opportunity involving the treatment of liquid pig manure using magnesium smelting by-products. Description The problem: Swine manu..

Antimicrobial technology against Antibiotic Resistant Bacteria

A team at Agriculture and Agri-Food Canada (AAFC) has discovered a formulation of a new group of active antimicrobial ingredients based on a novel mechanism of protection of β-lactam antibiotics agai..

Neuroprotective Agent for the Treatment of Ischemic Stroke

Novel neuroprotective peptide agent capable of reducing the amount of ischemic brain injury. Description Researchers at the Centre for Addiction and Mental Health have developed a novel neuroprot..

SIGMA2

A system for the integrative genomic multi-dimensional analysis of cancer genomes, epigenomes, and transcriptomes

Asthma Quiz for Kidz

The Asthma Quiz for Kidz is a simple and attractive self-administered 6-item questionnaire to assess asthma control in children and adolescents. A score of 2 or more is indicative of poor asthma contr..

Quiz sur l'asthme pour les jeunes

Le Quiz sur l'asthme pour les jeunes est un questionnaire de 6 questions auto administré, simple et amusant servant à l'autoévaluation de la maîtrise de l'asthme chez les enfants et adolescents. U..

Teste sobre a asma para crianças

The Asthma Quiz for Kidz is a simple and attractive self-administered 6-item questionnaire to assess asthma control in children and adolescents. A score of 2 or more is indicative of poor asthma contr..

PARA-SCI: The Physical Activity Recall Assessment for People with Spinal Cord Injury

A reliable and validated tool for measuring physical activity among people with Spinal Cord Injury. Available for download together with guidelines and scripts for administering the tool. Now availabl..

CONTROLLING T LYMPHOCYTE MEDIATED IMMUNE RESPONSES (RDLP#348)

The present invention relates to a prominent peptide epitope, ABBOSS or BSA148 that is targeted by abnormal immunity in autoimmune diseases such as Rheumatoid arthritis, Type 1 diabetes, and primary S..

University of Nebraska-Lincoln Technology Out-Licensing Opportunities

The Lincoln, Nebraska-based Office of Technology Development (OTD): http://otd.unl.edu/ manages the intellectual property assets of the University of Nebraska-Lincoln. OTD’s mission is to help turn ..

IMMORTALIZED RAT SKELETAL MUSCLE CELLS (L6) EXPRESSING GLUT4MYC GLUCOSE TRANSPORTER (RDLP#437)

The inventors have created an L6 myoblast cell line that stably expresses the GLUT4 protein containing a fourteen amino acid Epitope of human c-myc within its first exofacial loop Background In..

L6 RAT SKELETAL MUSCLE CELLS (RDLP#429)

The inventors have subcloned an L6 myoblast cell line that was selected for high fusion capacity as these cells differentiate into myotubes. Background Approximately 40% of people with diabetes ..

Biomarkers for Heart Failure and Death

This technology uses a novel biomarker panel for predicting heart failure and death in an ACS population. Description Patients who present with chest pain at the emergency department may have p..

Construction of Tissue Microarrays from Needle Biopsies

Simple, fast technique for re-embedding. Any experienced technician can use this method without special training or additional materials or instruments. Description Tissue microarray (TMA) techn..

Diagnostic Method to Detect Endometriosis

A non-invasive development of a test for the diagnosis and monitoring of endometriosis. Description The endometrium is the tissue that lines the uterus and is normally shed each month during the..

Easier, Safer and More Effective Oncolytic Viral Therapy

This innovative therapy exploits the species specificity of both interferon and the Herpes viruses to produce a safer, more effective and easier to produce oncolytic viral therapy. Description On..

High Efficiency mRNA Translation

Researchers at McMaster University have devised a novel method that involves the coupling of specific nucleotide sequences at the 5'- and 3' -ends of a nucleic acid molecule transcribable to the mRNA ..

New Tool to Investigate Protein Interactions

This platform technology is a unique, alternative, high-throughput method for investigating the functions of intact proteins, in their native state, in vivo and identifying protein interactions. It ov..

New Tools Against Thrombotic Disease

The McMaster technology presents a significant step towards the treatment and management of pathological thrombosis and embolism. Novelty This discovery is unique in targeting the molecular ..

Non-invasive Test Assists Treatment Decisions for Cancer Patients

This non-invasive test can be used as a tool to predict responses to radiation therapy in cancer patients, and therefore is a huge step forward in determining treatment decisions in cancer patients. ..

Novel Antibacterial Target and Novel Antibiotic

This technology targets a novel antimicrobial target, that of lipoprotein biosynthesis in Gram-negative bacteria. Description Multidrug-resistant bacteria are a growing problem in health-care. Th..

Novel Therapeutic Target for ER Stress Related Diseases

The patent on this McMaster proprietary technology claims a therapeutic benefit whereby manipulating the expression of this protein may prevent premature atherosclerosis. Description Novelty ..

Targeting Collagen Synthesis for the Treatment of Malignant Tumours

A novel cancer therapeutic with particular relevance for tumours that have a high degree of fibrosis such as breast cancer & pancreatic cancer Description Novelty Current methodologies to inh..

Premenstrual Symptoms Screening Tool (PSST)

Developed by researchers at McMaster University, the Premenstrual Symptoms Screening Tool (PSST) is an instrument to measure the severity and impact of premenstrual symptoms and a timely qualification..

Streptogramin Antibiotics

Class B streptrogramin antibiotics that are impervious to resistance. Description Streptogramin antibiotics such as the agriculturally valuable virginiamycins (Stafac®) and the clinically import..

Method to Rapidly Search and Classify DNA Barcodes

A very rapid search algorithm that was specifically developed to search through large databases of small regions of DNA. Description A DNA barcode is a relatively short sequence of genomic DNA th..

BHV-1 Neutralizing scFv Antibody

Recombinant single chain variable fragment (scFv) antibody capable of neutralizing Bovine Herpes Virus Type-1 (BHV-1) Description BHV-1 is an important pathogen of cattle, which causes a variety..

Vaccine for Necrotic Enteritis in Poultry

Several target antigens suitable for use in a vaccine against Clostridium perfringens infection in poultry, enabling control of necrotic enteritis without antibiotics Description Necrotic enterit..

Enviropig™

Pigs with the ability to utilize efficiently phytate phosphorus (P) that is present in plant feed ingredients. Background Most phosphorus in plants is present in the phytate form. Conventional mo..

Genetic Methods to Reduce Boar Taint in Entire Male Pigs

The University of Guelph is actively developing a genetic tool kit that will be useful in breeding entire male pigs that are low in androstenone and skatole, the main components of boar taint. Descrip..

New Vaccine Methods

Membrane vesicles from Gram-negative bacteria can be used in vaccines Description Many gram-negative bacteria produce membrane vesicles during normal growth. These membrane vesicles have all of t..

Prion Detection Method

Guelph researchers have developed a rapid method to detect prion proteins that are the cause of transmissible spongiform encephalopathies (TSEs) in mammalian species. Description A rapid method h..

Bioactive paper for detection and removal of organophosphates and lactones

Bioactive paper containing a thermostable enzyme capable of degrading organophosphate, organosulfur, and acylhomoserine lactone compounds Advantages Wide range of potential applications Thermost..

Artificial Truffles

An inexpensive version of the rare and expensive French truffle, deemed similar in taste and texture by local truffle experts. Developed at the University of Guelph. Description French truffles a..

Mint Variety Useful for Treating Allergies

A mint variety that produces very high levels of rosmarinic acid, a powerful antioxidant and anti-inflammatory. Developed at the University of Guelph Description Guelph researchers have developed..

Novel Food Oil Structuring Product

A new class of organogelator that is derived from foods such as soybean and dairy products. Background The structure of many food products is based on triacylglycerol from a hardstock. While the ..

Novel Probiotic Extracts

Bioactive compounds from probiotic bacteria that have been shown to prevent infection by harmful bacteria such as E. coli and Salmonella. Background Probiotic bacteria have long been shown to hav..

Gene Related to Peroxisomal Disorders

A gene to enable the study plasmalogen deficiency and its role in human disease Description This invention consists of the gene and promoter for ethanolaminephosphate cytidylyltransferase (ECT). ..

Novel Antibiotic Targets

Due to the continued emergence of drug- resistant bacteria, there is an increasing need for new targets and new therapies for antibiotic treatment. This invention consists of novel bacterial targets t..

Novel Synthetic Lung Surfactants

A significant improvement over current animal-derived and synthetic exogenous preparations, this synthetic preparation has chemical constituents that greatly enhance their stability against lipase deg..

Potential Treatment for Polycystic Kidney Disease

This invention relates to method to treat polycystic kidney disease (PKD) using a saponin-enriched alcohol extract from soy protein isolate. Kidney morphometric analysis shows that mean cyst volume, a..

Uterine Diagnostic Tools for Potential Pregnancy

Uterine natural killer (NK) cells are required during pregnancy to maintain the integrity of the decidualized uterine stroma and for initiating decidual artery instability. Inadequate quantities of th..

Harvest Inducible Promoter

Three plant promoters and a method to locate other plant promoters that are only induced upon harvest have been identified in alfalfa. Advantages The present invention offers a number of competit..

Phytoremediation Using Geraniums

The invention relates to the use of geraniums (Pelargonium spp.) to remediate soils contaminated with heavy metals. The plants surpass all of the requirements for an ideal hyperaccumulator including r..

Elite Medicinal Plants

Guelph researchers have developed a method to produced standardized, elite medicinal plants with high yields of active ingredients. Major problems with existing methods to produce medicinal plants are..

Automated Solid-Phase Analytical Derivatization in Minutes

This innovative McMaster device is the first to integrate an autosampler and analytical column enabling sample isolation, analytical derivatization and instrument analysis via high pressure liquid chr..

Radiation Triage Mask

A facial mask device to be used by First Responders that will rapidly determine who has/has not been exposed to radiation, what radioisotope at what does. This device, that detects alpha, beta and gam..

Engineered Burkholderia for Bioremediation

A non-pathogenic strain of Burkholderia provides tremendous potential as a bioremediation agent particularly for degradation of PCBs or for sites with high TCE concentrations. Background The inte..

Non-Pathogenic Burkholderia Strain

A non-pathogenic strain of Burkholderia cepacia provides an opportunity to develop a live vaccine to prevent Bcc infection in CF and critically ill patients, which would dramatically improve the quali..

Novel Protein Translation Inhibitor

A novel drug target and peptide(s) designed to inhibit protein synthesis by specifically preventing formation of the 43S preinitiation complex Background The global cancer market was valued at US..

A non-invasive test of oocyte quality in assisted conception

An innovative, real-time test of oocyte quality, applicable to assisted conception treatments, that does no harm to the oocyte itself. Background Assisted conception treatments have become essent..

Diagnostic System for Early Stage Osteoarthritis and Therapeutic Discovery

The present invention relates to osteoarthritis (OA) and methods of OA diagnosis and treatment via the findings of a genome-wide analysis of dysregulated genes in OA. Background OA is the most pr..

Novel Therapeutic Approach to the Prevention and Treatment of Staphylococcus Aureus Infections

A suite of highly specific, proprietary bacterial drug targets in staphylococcus aureus, that can be used individually or as a group to develop small molecule or peptide drug leads with powerful anti-..

Target for the Diagnosis and Treatment of Osteoarthritis

This technology is based on changes in the protein expression profile of osteoarthritic cartilage, which represents an opportunity to develop diagnostic kits and targeted therapies for OA. Background ..

New Powerful Tool for Monitoring of Kinase Activity

A powerful technology for the simultaneous monitoring of protein kinase activities in cell and tissue extracts using a multiplexed electrochemical assay Background In the cellular signaling netwo..

Opure: Safe handling of drinking water

Safe drinking water is a major issue in most developing countries, where improvements in its use, management and quality are greatly needed. We propose a design of jar which keeps clean water clean wh..

Novel Compounds for Inhibiting Abnormal Cell Proliferation (RDLP# 510)

This technology consists of: (1) a group of novel compounds useful for modulating abnormal cell proliferation, (2) a pharmaceutical composition, (3) a method modulating cell proliferation, (4) a proce..

Unique Treatment for Type 2 Diabetes and Islet Cell Transplantation (Ref. #1354)

Our technology is a peptide therapeutic that prevents the formation of IAPP aggregates. These 3-6 amino acid peptides have been shown to improve islet cell survival in vitro so more cells are availabl..

Thermal Dependent Injectable Polymer Matrix (Ref. #1421)

The technology is a novel drug delivery polymer matrix comprising an inverse thermal gelling polymer with an anionic polymer. This polymer matrix is faster gelling than each of the separate components..

Nano-Composite Polymeric Membrane System for Drug Delivery (Ref. #1496)

The invention is a composite polymeric system to provide enhances stimuli-responsiveness. The first aspect provides particles including nanoparticles or microspheres in which the particles are made of..

Novel Supramacromolecular Polymer Complexes Providing Controlled Nitric Oxide Release for Healing Wounds (Ref. #1489)

To overcome these deficiencies, UofToronto researchers have developed a novel, stable and biocompatible system for generating a durable release of NO. This technology is based on the discovery that a ..

Linker Microemulsions as a Transdermal Drug Delivery Vehicle (Ref. #1452)

The development of formulations based on low-toxicity and/or natural ingredients represents a clear solution to this problem, especially for longer-term or continual use applications common to the cos..

Mitochondria Penetrating Peptides (Ref. #1512)

The inventors have developed a new class of CPPs called mitochondria penetrating peptides (MPPs) that exhibit the unique characteristic of specifically localizing to the mitochondria. These MPPs, can ..

Chip-Based Platform to Investigate Small Arteries (Ref. #1519)

The chip-based platform is a technology that greatly improves experimentation with microvessels. This polymer chip accurately mimics a physiological environment in which a microvessel can be loaded an..

Compounds for Modulating Cell Proliferation (RDLP# 499)

The technology relates to benzene substituted derivatives of halogen-, aryl- and alkoxy-substituted cyanoester compounds and their use for treating a variety of cell proliferative disorders including ..

A prognostic test for B-cell chronic lymphocytic leukemia (Ref. #1494)

Researchers at Sunnybrook Health Sciences Centre have developed a prognostic test that indicates whether a B-CLL patient is in the indolent or aggressive stage, and therefore whether treatment should ..

Monitoring Cell Response to DNA-Damaging Agents (RDLP# 554)

This invention relates to methods (1) for using biodetectors to monitor cellular responses to stress in particular to DNA damage-inducing agents (2) methods for monitoring the efficacy of anti-cancer ..

Novel Phospholipid Compositions and Biomarker for the Diagnosis and Treatment of Lung Disease (RDLP# 525)

This invention includes: (1) phospholipids PC formulations for patients with lung disease and pathology related to decreased surfactant levels, (2) a biomarker/clinical indicator for identifying reduc..

ß-parvin Acts as a Tumor Suppressor in Breast Cancer Through Inhibition of ILK Signaling (RDLP# 513)

ß-parvin inhibits ILK signaling and suppresses cellular transformation in breast cancer. Background ß-parvin is a widely expressed member of a family of adaptor proteins, which are implicated ..

Susceptibility Gene for Inflammatory Bowel Disease (RDLP# 540)

The inventors have identified three SNPs in the receptor protein tyrosine phosphatase sigma gene (PTPRS), which are associated with UC, and one associated with CD. Background It is estimated tha..

Novel Bioreactor for Urinary Bladder Dysfunction and Repair (RDLP# 583)

The invention consists of a urinary bladder tissue bioreactor and customized software that allows for dynamic mechanical cell stimulation and stretching. Description The invention consists of: ..

EOS Vectors Select for Pluripotency During iPS Cell Reprogramming (RDLP# 605)

This invention relates to the creation of a novel stem cell expression cassette called EOS that restricts reporter expression to embryonic or induced pluripotent stem cells.

Novel Molecular Diagnostics for Multiple Sclerosis (RDLP# 614)

The invention relates to a method of diagnosing multiple sclerosis (MS) via an in vitro test. Background Over 2.5 million people globally suffer from Multiple Sclerosis (MS). With the present gl..

Novel Strategy in Manipulation of Stem Cell Fate Specification

A novel methodology of regulating and inducing stem cell differentiation by altering the expression of a key protein that is naturally existing and participating in embryo development. Background ..

Novel Disposable Contact Lens Based Glucose Biosensor

A novel disposable contact lens biosensor for the continuous, non-invasive monitoring of physiological glucose for diabetic patients. Background In diabetes mellitus, insulin production and/or ..

Adapter Gene (RDLP#457)

This invention consists of the identification and cloning of a novel gene, MARS (Modulator of Antigen Receptor Signaling). MARS is a putative tumour suppressor gene. Background An estimated 44,2..

METHODS OF ASSESSING SEVERITY OF PULMONARY DISEASE AND ITS TREATMENTS (RDLP#589)

The present invention relates to the development of a molecular DNA-based test for genetic variants, which are predictive of higher susceptibility to bacterial infections and severe pulmonary disease ..

ILK-Mediated Stem Cell Proliferation as a Novel Therapy for Acute Cardiac Damage (RDLP# 528)

The invention relates to a therapeutic method to promote cardiac repair after acute myocardial damage through the activation of ILK, stem cell proliferation, migration and survival Background Rec..

ILK-Induced Cardioprotection as Novel Prophylaxis and Therapy for Acute Cardiac Damage

The invention relates to a method to promote cardiac protection through ILK induced ventricular hypertrophy. Background Recent advances in cardiac physiology identify the integrin-linked kinase (..

NH-7211 – A Broad Acting Anti-Alzheimer’s Compound

Novel small chemical compounds capable of disrupting the three key misfolded proteins responsible for Alzheimer’s disease (AD) and other CNS disorders Description Our researchers have created n..

GRASS CARP SALES

Lethbridge College, Alberta has an Aquaculture Center of Excellence (ACE) that produces sterile Grass Carp for aquatic vegetation control. In Alberta retail buyers can purchase Grass Carp from license..

Sox17 Expressing Human Embryonic Stem Cells–Endodermal Progenitors (RDLP# 613)

The invention of a stable endoderm progenitor cell line established from hES cell lines by constitutive expression of Sox17-producing definitive endoderm progenitors. Background Human embryonic ..

Investor Wanted: $125K. DIABETIC PROJECT

Assignment of Interest in Private, close company in international marketing / due diligence phase with potential buyers / licensees. Owns international patents applied for and have completed successfu..

Antimicrobial Peptides (RDLP# 450)

The inventors have developed a new class of proprietary peptides with active antibiotic properties Description The inventors have developed a new class of proprietary peptides with active antibio..

Retinal Stem Cells (RDLP# 383)

The invention relates to the isolation of stem cells from both embryonic and adult mouse retina as well as adult human retina, and includes a method for stimulating proliferation of endogenous retinal..

Novel Susceptobility Biomarkers of Autism (RDLP# 642)

The invention relates to the identification of structural genetic variants (copy number variations/CNV) of chromosomes in individuals with Autism Spectrum Disorder. Background Genomic abnorma..

Neural Crest Stem Cells and Uses Thereof (RDLP# 494)

Background Since stem cells are multi-potent and self-renewing, they may be used as starting material for the production of cell types to replenish lost tissue material in cases when a disease, d..

Novel Chemical Entities Affecting Neuroblastoma Tumour-Initiating Cells (RDLP# 536)

Candidate NB tumor-initiating cells (TICs) have been isolated, and it has been hypothesized that TICs are related to SKPs (Skin-derived Precursors). Background Malignant neuroblastoma (NB) is th..

NutriSTEP™

A nutrition risk screening tool for preschool children, aged 3-5 years. Valid, reliable, bilingual (English and French). Description NutriSTEP™ is a fast and simple way to assess eating habits..

NMQC: A NEMA-based software application for quality control of gamma cameras

UBC researchers have developed a NEMA-compliant software application that functions across manufacturer platforms and allows the user to monitor performance over time Background The NMQC software..

Human Lipase Cell Lines

Background Technology Details: Human hepatic lipase cell line - Chinese hamster ovary (CHO) cells have been stably transfected with a human hepatic lipase cDNA to overexpress this enzym..

Epilepsy, Alzheimers & Parkinson's Drug Development

Upsher-Smith Laboratories, Inc., is a privately held, specialty pharmaceutical company with headquarters in Minneapolis, MN (www.upsher-smith.com). The company is seeking collaborative partners and ou..

Drug Delivery Technologies

Upsher-Smith Laboratories, Inc., a privately held, specialty pharmaceutical company with headquarters in Minneapolis, MN (www.upsher-smith.com), is actively seeking Canadian companies or research orga..

Women's Healthcare

Upsher-Smith Laboratories, Inc., a privately held specialty pharmaceutical company with headquarters in Minneapolis, MN (www.upsher-smith.com), would like to augment its current portfolio with markete..

FEITER A NEW METHOD OF BRAIN SCANNING

BACKGROUND A number of techniques are available for brain scanning and imaging including CT scanners, MRI, fMRI and PET. All require large expensive fixed installations and cannot be made available in..

NOVEL SYNTHESIS OF IDURONATE A HEPARAN SULPHATE SUBUNIT

BACKGROUND Heparan sulphate and heparin play a central role in a large number of processes including anti-coagulation, angiogenesis, cell growth and migration. A new class of medicinal drugs can be en..

Zero Bias Switch

ZBS (Zero Bias Switch) patent # 7,106,188 A long range radio receiver without an amplifier (no battery drain) This RF receiver is acitvated by the incoming signal no stand-by power is needed. ..

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