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Medical Devices Technologies for Sale or License

The following are Medical Devices technologies offered for sale or license. Viewing technologies for sale is a free service of IdeaConnection.com, as is connecting with the seller if a technology interests you. Click on a heading below for more information.

Medical devices help doctors, nurses, and researchers diagnose, treat and monitor sick patients. Medical devices include implantable devices such as stents and defibrillators, and diagnostic devices such as x-ray machines and thermometers. Post your medical device technology for sale or license here.

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Medical mask for seizure suppression and prevention

Membrane breathing mask for fast and effective suppression of epileptic fits, febrile seizures and hyperventilation attacks Inventor: Troels Johanen (M.Sc.Eng.), ph.d. student at Aarhus University..

ULTRASOUND FOR LOCATING ANATOMY OR PROBE GUIDANCE

A hand-held apparatus can be used to assist in guiding a probe or locating a particular anatomical target in a subject. The apparatus can include an ultrasonic transducer located on or within a housin..

NON-INVASIVE SYSTEMS AND METHODS FOR IN-SITU PHOTOBIOMODULATION

Products, compositions, systems, and methods for modifying a target structure which mediates or is associated with a biological activity, including treatment of conditions, disorders, or diseases medi..

Hip joint orthosis for e.g. supporting musculature of patient after hip joint implantation, has electro stimulation device for generating electro stimulation, where beginning and ending of stimulation

The orthosis has a hip belt including three parts in the form of shell elements (1), which are movably arranged and fixed on a flexible anti-rotation cable. An orthosis joint (5) includes an adjustabl..

Bite guard splint i.e. lower jaw bite guard splint, for keeping open of respiratory tract at asleep of patient, has fastening elements provided for connection element to piercing-like implant at regio

The splint (13) has fastening elements (14) e.g. hooks (15), for a connection element (17) e.g. fastening lug, to a piercing-like implant at a region of a tongue body of a patient. The fastening eleme..

MAGNETICALLY MOUNTED ARTIFICIAL JOINT

The invention relates to a prosthesis for replacing a joint compound in the same magnetic fields of joint head 10, socket 12 and pivot collar 14 can be superimposed so that the repulsive forces produc..

REPOSITIONING DEVICE FOR THE HANDLING OF DISTAL RADIUS FRACTURES BY MEANS OF A T-SHAPED OSTEOSYNTHESIS PLATE

The invention relates to a repositioning device for the handling of distal radius fractures by means of a T-shaped osteosynthesis plate, comprising a long leg and a short leg, disposed in a T-shaped a..

Device for ventilating the middle ear, has stent having hollow cylinder which has funnel-shaped expansion at two ends, where inner diameter of hollow cylinder lies in certain range

The device has a stent (10) having a hollow cylinder (12) which has a funnel-shaped expansion (18) at two ends (14,16). The inner diameter of the hollow cylinder lies in the range of 0.5 millimeter to..

DEVICE FOR IN SITU MILLING OF JOINT SURFACES

The invention relates to a device for in situ milling of joint surfaces, comprising a milling device (20 24) and a joint clamping device (10). The invention further relates to a use of a corresponding..

METHOD FOR DETERMINING THE CLAMPING FORCE ON A MECHANICAL JOINT CONNECTION CONNECTING AT LEAST TWO COMPONENTS

The invention relates to a method for determining the clamping force on a mechanical joint connection connecting at least two components by coupling sound waves into the joint connection. The inventio..

Device for testing endurance limit of medical device, has two fixing devices at end cross sections of medical device, and two actuators which are coupled with fixing devices

The device (1) has two fixing devices (3,4) at the end cross sections of a medical device, and two actuators which are coupled with the fixing devices. The device has a guiding element (10) at which t..

Medical implant i.e. flexible hollow implant, for ventilation of middle ear in head of human, has flexible peristalsis elements assigned to implant and causing pressure balance between openings on imp

The implant i.e. flexible hollow implant (5), has peristalsis elements flexible over entire length and assigned to the flexible hollow implant and causing pressure balance between distal and proximal ..

MEDICAL IMPLANT FOR TREATING ARTHRITIS IN JOINTS OF THE HUMAN OR ANIMAL BODY

The invention relates to a medical implant for treating arthritis in joints of the human or animal body, in particular in the knee joint of a patient. In order to prevent extensive means for inserting..

DEVICE AND METHOD FOR MEASURING TIBIAL TRANSLATION

The invention relates to a device and a method for measuring tibial translation in mammals under loading. The device has at least a first and a second splint, which can be fastened laterally to the up..

SUTURE ANCHOR SYSTEM

The invention relates to a suture anchor system for fixing sutures to bone, having a screw, an adjacent anchor, a cannulation in the anchor, and a thread, wherein the anchor comprises two opposite ind..

ORGANIZATION AND SECURITY SYSTEM FOR FUNCTIONAL CONNECTIONS

The invention relates to a device for separating functional connections, in particular in the medical field, for example infusion and perfusion lines, but also to cable connections from and to medical..

CELL COATED IMPLANTABLE DEVICE

The present invention relates, in general, to a cell-coated implantable medical device and, in particular, to an implantable medical device the blood-contacting surfaces of which are coated with endot..

APPARATUS FOR OCCIPITO-CERVICAL FIXATION ENABLING SUPPLEMENTAL OCCIPITAL BONE FIXATION

An apparatus for stabilization of a patient's head relative to the patient's neck joint includes an occi-cervical base member having a "C '-shaped central part and first and second attachment rods res..

TRANSLATIONAL MANIPULATION POLYAXIAL SCREW HEAD

A novel surgical screw is presented as a polyaxial, multiaxial, or monoaxial screw. The polyaxial screw allows versatile angulation between a bone anchor section and a screw body and allows the surgeo..

Intracranial Catheter and Methods of Use

A catheter assembly for intracranial treatment of a subject that includes an outer tube that may be connected to an infusion or osmotic pump and delivered through a bendable catheter to the target bra..

BLADDER DRAINAGE AID

Provided is a bladder drainage aid which attaches to the end of Foley Catheter and removes the need for a catheter bag. In a preferred embodiment, the device is a spring-loaded valve with an inflow tu..

APPARATUS FOR OSTEOTOMY AND GRAFT PREPARATION

Surgical tools that increase surgical accuracy for orthopedic procedures involving long bone osteotomy with or without supplementation with allograft or autograft. Two clamps on the operative side are..

TRANS-ENDOSCOPIC HYDRAULIC BALLOON APPARATUS

A trans-endoscopic hydraulic balloon dilation apparatus includes a fluid reservoir containing a hydraulic fluid. A shaft has a lumen in fluid communication with a leading end of the fluid reservoir. A..

ENDOSCOPIC OVERTUBE

An over-tube was developed for receiving and guiding endoscopic instruments into a patient's anus, through the colon, and into the peritoneum. The over-tube has a flexible sheath adapted for insertion..

Cervical plate system

An anti-subsidence, anti-translocation, fusion compression cervical plate system with interface visualization, drill guide and temporary pin is provided. In one embodiment the invention provides a ver..

EMBOLECTOMY STROKE DEVICE

Devices and methods for removing an obstruction from a blood vessel are described. The devices are deployed in a collapsed condition and are then expanded within the body. The devices are then manipul..

PREDETERMINED PRESENTATION OF PATIENT DATA AT BEDSIDE

Techniques for presenting patient data at the patient's bedside include receiving predetermined presentation style data that indicates a subset of fewer than all parameters available from an electroni..

HOLDING DEVICE, BITE ELEMENT AND SYSTEM FOR INTRAORAL RADIOGRAPHY

The invention relates to a bite element, a holding device, a method, a computer program product and a system for creating and/or processing intraoral shadow images, in particular X-ray images. To this..

DEVICES AND METHODS FOR PERCUTANEOUS ACCESS, HEMOSTASIS, AND CLOSURE

The present invention provides methods and devices for obtaining percutaneous access, maintaining hemostasis, and providing closure of openings in tissues of the body. In particular, the present inven..

FLUID CONTAINMENT APPARATUS

The invention relates to the treatment of wounds. In particular, the invention relates to systems, devices, and methods enabling pulse lavage irrigation of wounds in a non-controlled setting while pro..

ABLATION DEVICES AND RELATED METHODS THEREOF

The present invention relates generally to devices for performing targeted tissue ablation in a subject. In particular, the present invention provides devices configured to deliver energy to a targete..

DEVICES FOR MATERIAL DELIVERY, ELECTROPORATION, AND MONITORING ELECTROPHYSIOLOGICAL ACTIVITY

The invention relates generally to devices for material delivery, electroporation and monitoring electrophysiological activity. In particular, the present invention provides devices and systems config..

APPARATUS AND METHOD FOR AIRWAY PATENCY AND HEAD IMMOBILIZATION

A jaw-thrust device includes a base with an extension arm disposed on each side of a patient's head mounted on the base. A mandible rest is mounted on each extension arm such that the mandible rest ma..

METHODS AND DEVICES FOR ARYTENOID REPOSITIONING

Methods and devices for repositioning the arytenoid cartilage of a human subject are disclosed.

AGR-MEDIATED INHIBITION AND DISPERSAL OF BIOFILMS

The present invention involves the use of activators of bacterial agr quoroum-sensing systems to block, inhibit or reverse biofilm formation. The biofilm may be located on an industrial or medical sur..

FASTENER DEPLOYMENT SYSTEM AND METHOD

This document discloses, among other things, a long reach, side ejecting fastener placement apparatus suitable for use in nasal septal surgery. A first linear member carries a fastener body and a seco..

TISSUE AND OBJECT RETRIEVAL DEVICE AND SYSTEM

The invention described herein provides a device for tissue and/or object retrieval constructed for use with minimally invasive medical procedures. By virtue of its construction and operation, the dev..

TREATMENT AND PLACEMENT DEVICE FOR SINUSITIS APPLICATIONS

Devices, methods and kits which, when installed or used, access, aspire, dilate, insufflate, drain or deliver fluid medicaments to, or place a patency device within a sinus area, such as a maxillary s..

IMPLANTABLE DEVICES FOR TREATMENT OF SINUSITIS

Devices, methods and kits which, when installed or used, urge or maintain patency of sinus ostia, such as the ostium between a nasal passageway and a maxillary sinus, while maintaining some function o..

SPINAL PROBE WITH TACTILE FORCE FEEDBACK AND PEDICLE BREACH PREDICTION

A spinal probe (10) comprises a handle (18), a shaft (20) coupled to the handle and a force sensor (14) to detect forces applied to a tip of the shaft. A controller that executes a predictive algorith..

CATHETER INSERTION STERILIZATION

A device includes a sheath having a lumen defined by a wall. The wall has an outer surface that is configured to emit ultraviolet light in a direction substantially normal to the wall. The lumen has a..

BIOACTIVE PEPTIDE FOR CELL ADHESION

Implantable devices for adhering eukaryotic cells and devices providing a substrate for eukaryotic cell growth and/or differentiation in vitro are described. Each device comprises a scaffold that is c..

INTELLIGENT POWERED MOBILITY FOR INFANTS AND SPECIAL NEEDS CHILDREN

A powered mobility device for advancing cognitive, perceptual and motor abilities of a child lacking natural mobility is disclosed. The device includes a seat sized for the child to be secured therein..

DYNAMIC VIBRATIONAL METHOD AND DEVICE FOR VOCAL FOLD TISSUE GROWTH

Dynamic vibrational methods and devices for inducing differentiation of stem cells into vocal fold fibroblast-like cells or for generating vocal fold-like tissue from cultured cells. Also provided are..

Delivery System For Heparin-Binding Growth Factors

A device comprising a scaffold coated with a protein having at least 83% identity to the amino acid sequence of the core protein of domain I of a mammalian perlecan, wherein at least one glycosaminogl..

IMAGE-BASED CONTROL SYSTEMS

Image-based control systems and methods automate the adjustment of medical devices. An image based-control system for an endoscope can include, in addition to the endoscope, a processing system and an..

TARGETING THERAPEUTIC AGENTS

Provided are devices, systems, and methods for targeted administration of therapeutic agents to a subject. For example, provided are devices, systems, and methods for targeting the administration of p..

DEVICES AND METHODS FOR MODULATING BRAIN ACTIVITY

Devices and methods for brain modulation are provided herein. A device may comprise a body and components for activating the brain. Such components include ultrasound transducers. The devices are used..

NEUROSTIMULATOR

Methods and devices of stimulating nerves are disclosed. In one embodiment adapted for stimulating excitable tissue, the invention includes drive circuitry (12), an acoustic transducer (14) and a pair..

ROTATING NEEDLE DRIVER AND APPARATUSES AND METHODS RELATED THERETO

Featured is a medical instrument driver, a robotic apparatus embodying such a medical instrument driver and methods related thereto for inserting a medical instrument into tissue of a mammal (e.g., hu..

CYLINDRICAL ILLUMINATION CONFOCAL SPECTROSCOPY SYSTEM

A cylindrical illumination confocal spectroscopy system has a fluidic device having a fluid channel defined therein, an objective lens unit arranged proximate the fluidic device, an illumination syste..

ARTICULATED DEVICE WITH VISUALIZATION SYSTEM

An articulated device may include a first steerable multi-linked mechanism and a second steerable multi-linked mechanism. The second steerable multi-linked mechanism may include a first link, a plural..

INSERTABLE SURGICAL IMAGING DEVICE

A body-insertable imaging device includes a first camera that comprises a first image sensor and a first lens to pass incident light onto the first image sensor, a control interface to receive a remot..

SYSTEMS AND METHODS FOR INSERTING STEERABLE ARRAYS INTO ANATOMICAL STRUCTURES

Systems and Methods are provided for inserting a steerable array into an anatomical structure of the body. The system includes an insertion module for holding a proximal end of the steerable array and..

INHIBITING STAPHYLOCOCCUS EPIDERMIDIS INFECTIONS

The invention relates to Staphylococcus epidermidis peptides, antibodies and nucleic acids that can inhibit Staphylococcus epidermidis infection of a mammalian subject and colonization of a medical de..

Medical implant and method of its manufacture

The implant has an outer mantle layer consisting of a set of coils (10) movably arranged to each other in a longitudinal direction. A hollow space is provided between the coils, which exhibit conicity..

MEDICAL IMPLANTS, PROSTHESES, PROSTHESIS PARTS, MEDICAL INSTRUMENTS, DEVICES AND AUXILIARY CONTRIVANCES MADE OF A HALOGENIDE-MODIFIED MAGNESIUM SUBSTANCE

The use of a magnesium substance, whose corrosiveness is altered as a result of modification with halogenides, enables medical implants, prostheses or prosthesis parts and medical instruments, devices..

FIXATION DEVICE AND METHOD FOR SOFT TISSUE GRAFTS

An expandable medical device for surgical implantation that secures the ends of a soft tissue graft in a tunnel made in bone, such as in ligament replacements. The graft material is positioned between..

ARRAYED DETECTOR SYSTEM FOR MEASUREMENT OF ANTI-VIRAL IMMUNE RESPONSE

A sensor chip for detecting an immune response against a virus, the sensor chip including a substrate having a surface and a plurality of virus-like particles or capsid fragments bound to discrete loc..

Device and method for disinfecting stethoscope heads

A device for disinfecting a head of a stethoscope has a receiver adapted to hold a supply of disinfecting agent. A dispenser that is mounted to reciprocate relative to the receiver has a receptacle fo..

DNA MICROARRAY HAVING HAIRPIN PROBES TETHERED TO NANOSTRUCTURED METAL SURFACE

A sensor chip and detection device are disclosed. The sensor chip includes a substrate, at least a portion of which is covered by a metal nanoparticle film; a first nucleic acid molecule that is chara..

INTRAOCULAR PRESSURE REGULATING DEVICE

Systems and methods are described for implanting a device in a mammalian eye to raise intraocular pressure. In some embodiments, the device (54) includes an arcuate body that, when implanted, obstruct..

ARRAYED DETECTOR SYSTEM FOR MEASUREMENT OF INFLUENZA IMMUNE RESPONSE

A sensor chip for detecting an immune response against an influenza virus, the sensor chip including a substrate having a surface and a plurality of hemagglutinin polypeptides bound to discrete locati..

CMOS IMAGE SENSOR ON STACKED SEMICONDUCTOR-ON-INSULATOR SUBSTRATE AND PROCESS FOR MAKING SAME

Methods and apparatus for producing a CMOS image sensor result in a plurality of photo sensitive layers (A,B,C ); each layer including: a glass or glass ceramic substrate (102A, 102B, 102C) having fir..

SIMULTANEOUS AMBULATORY PULSE OXIMETRY AND PH MONITORING FOR THE DIAGNOSIS OF GERD-RELATED RESPIRATORY DISEASE

Respiratory diseases related to gastroesophageal reflux disease in a patient are diagnosed by detecting esophageal or pharyngeal impedance and pH in the patient, detecting oxygen saturation in the pat..

NEEDLE SHIELD FOR INJECTIONS

A needle shield for hiding a needle from a patient during an injection is disclosed. The needle shield comprises an attaching portion for attaching the needle shield to a syringe and an opaque collaps..

TRANSCUTANEOUS MAGNETIC ENERGY TRANSFER DEVICE

Transcutaneous magnetic energy transfer to drive a VAD or other implanted medical device can be supplied through two spinning (or otherwise moving) permanent magnets, or a moving permanent magnet and ..

GAS SYRINGE DEVICE

PROBLEM TO BE SOLVED: To provide a unit dose, gas-filled syringe which is filled with gas and packaged in a gas barrier material prior to use to increase shelf-life, that is, to minimize gas leakage a..

A SYSTEM AND METHOD FOR PATIENT SELF-ASSESSMENT OR TREATMENT COMPLIANCE

A system and method for transmission of alphanumeric messaging between mobile subscribers and an external system to send messages directly to the mobile subscriber's existing mobile phone to query the..

VERTEBRAL BODY REDUCTION INSTRUMENT AND METHODS RELATED THERETO

Featured is a reduction instrument being configured and arranged to allow correction of vertebral translation and applying distraction across a segment in an independent fashion. Such a reduction inst..

NASAL AIRWAY MANAGEMENT DEVICE WITH INFLATABLE SUPRAGLOTTIC LARYNGEAL CUFF

An airway management device such as, for example, an nasal airway management device with inflatable supraglottic laryngeal cuff is provided. The airway management device includes an airway tube, an in..

METHOD OF MAKING 3-DIMENSIONAL NEURAL PROBES HAVING ELECTRICAL AND CHEMICAL INTERFACES

A method of fabricating a three-dimensional neural probe includes the steps of: growing thermal oxide layer; depositing a layer of Au/Cr on the thermal oxide layer; patterning the layer of Au/Cr; depo..

DEVICE FOR COLLECTION AND PRESERVATION OF TISSUE OR STOOL SAMPLES

An arrangement for collecting a tissue or stool sample has a sample vial and a source of preservative fluid. A fluid valve controls a flow of the preservative fluid from the source of preservative flu..

Device and Method for Transfecting Cells for Therapeutic Use

This invention generally relates to devices and methods for transfection of living cells using electroporation, in particular high throughput microtluidic electroporation, and to therapeutic uses of t..

INTRINSIC HAND STRENGTH MEASUREMENT DEVICE

A device for measuring intrinsic hand muscle strength comprising an adjustable restraint adapted to restrain at least a portion of a hand, a force transfer member adapted to fit on or around one or mo..

ELECTROCARDIOGRAM RECONSTRUCTION FROM IMPLANTED DEVICE ELECTROGRAMS

A method of reconstruction of the standard 12-lead surface EKG given values of the electrical potential from an implanted medical device is described. This implanted device can be oriented in an arbit..

IMPLANTABLE DEVICE, SYSTEM INCLUDING SAME, AND METHOD UTILIZING SAME

An implantable device. The implantable device includes a computing device, a microelectromechanical system (MEMS) pH sensor connected to the computing device, and a communication system connected to t..

ELECTRODE SYSTEMS, DEVICES AND METHODS

An electrode system include a flowable and cohesive surface contact element comprising a hydrophilic polymer swollen with an electrolyte fluid, the contact element having a Q' ratio (A) of at least 5 ..

POWERED VEHICLE CONVOYING SYSTEMS AND METHODS OF CONVOYING POWERED VEHICLES

A vehicle convoy system for use in connection with a vehicle (for example a self-propelled wheelchair), wherein the vehicle includes at least one drive mechanism to impart drive to the vehicle, includ..

AN ECHO-SPECIFIC K-SPACE REORDERING APPROACH TO COMPATIBLE DUAL-ECHO ARTERIOVENOGRAPHY

A dual-echo sequence technique provided herein empowers simultaneous acquisition of both TOF MRA and BOLD MRV in a single MR acquisition. By this approach, an echo- specific K-space ordering scheme pe..

AUTOMATED ASSESSMENT OF OPTIC NERVE HEAD WITH SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPH

A fully automated optic nerve head assessment system, based on spectral domain optical coherence tomography, provides essential disc parameters for clinical analysis, early detection, and monitoring o..

INTRACORPOREAL GAS EXCHANGE DEVICES, SYSTEMS AND METHODS

A system for intracorporeal gas exchange includes a flexible, rotatable shaft; a plurality of axially spaced agitation mechanisms positioned on the rotatable shaft, such that the rotatable shaft can f..

COILS FOR MAGNETIC RESONANCE SPECTROSCOPY AND IMAGING OF HUMAN BREAST

System(s) and method(s) for magnetic resonance imaging and spectroscopy, and magnetic resonance spectroscopic imaging (MRSI) are provided. A unified heteronuclear coil system includes a volume coil tu..

SYSTEM FOR AT-HOME EYE MOVEMENT MONITORING

An apparatus for monitoring eye movement in a patient, includes a frame structured to be worn on the head of the patient. An infrared illumination device structured to illuminate an eye of the patient..

ARTICULATING LARYNGOSCOPE

Articulating laryngoscope to aid in the intubation of patients by providing illumination of the oral cavity and trachea during the process having, for example, 'fingers' with fiber optic lights at the..

JOINT BIOSCAFFOLDS

Provided herein are compositions and medical devices, and in particular, biodegradable scaffolds capable of repairing and replacing cartilaginous meniscuses. Also provided herein are methods of using ..

Cortical Control of a Prosthetic Device

A methodology for using cortical signals to control a multi jointed prosthetic device for direct real-time interaction with the physical environment, including improved methods for calibration and tra..

MAGNETIC DEVICE FOR GUIDING CATHETER AND METHOD OF USE THEREFOR

One or more external magnets that are suitable for placement on the back or front of a patient's neck and methods for using the external magnet(s) to guide a feeding tube containing one or more intern..

Paracorporeal respiratory assist lung

A paracorporeal respiratory assist lung (900), comprising a housing (920) having an outer body including an upper portion and a lower portion; an upper gas port (945) located on the upper portion; a l..

DETECTION AND QUANTIFICATION OF BIOMARKERS VIA A PIEZOELECTRIC CANTILEVER SENSOR

Quantification of a target analyte is performed using a single sample to which amounts of the target analyte are added. Calibration is performed as part of quantification on the same sample. The targe..

TWO-PIECE LIGHTWEIGHT LITTER SYSTEM

This invention is directed to a durable, compact, two-piece, light weight, load sustaining litter system for the transport of humans, animals or objects. The litter system comprises a litter frame, a ..

METHODS AND DEVICES FOR

The 'Smart Tool' includes a 'Smart Tool Probe' and two processing modules. The Smart Tool Probe is a hand held, wired or wireless, device that a surgeon utilizes for interrogating and identifying a ti..

APPARATUS FOR ATMOSPHERIC PRESSURE PIN-TO-HOLE SPARK DISCHARGE AND USES THEREOF

Disclosed herein are atmospheric pressure pin-to-hole pulsed spark discharge devices and methods for creating plasma. The devices include a conduit for fluidically communicating a gas, a plasma, or bo..

APPARATUS AND METHODS FOR DETECTING INFLAMMATION USING QUANTUM DOTS

Apparatus and methods for detecting an a biomarker indicative of an inflammatory condition, including a capillary tube adapted for one or more biomarkers to adhere to an interior surface thereof, a li..

INTRACRANIAL PRESSURE SENSOR

An intracranial pressure device for measuring CSF pressure in a skull includes a housing located between the scalp and the skull containing pressure device circuitry and a conduit extending downwardly..

CERVICAL SPINE PROTECTION APPARATUS AND METHODS OF USE

The invention is directed to a cervical spine protection apparatus one or more composite bands attached to provide restraint of one or more motions of the cervical spine of a wearer. The apparatus is ..

ALL ELECTRIC PIEZOELECTRIC FINGER SENSOR (PEFS) FOR SOFT MATERIAL STIFFNESS MEASUREMENT

A PEFS (Piezoelectric Finger Sensor) acts as an "electronic finger" capable of accurately and non-destructively measuring both the Young's compression modulus and shear modulus of tissues with gentle ..

BALLOON-ASSISTED ANNULUS REPAIR

The present invention is directed to an inflatable annulus repair device (10) for sealing an annulus defect located in an annulus fibrosis of an intervertebral disc space. In use, the inflatable devic..

DEVICES AND METHODS FOR DETECTING AND MONITORING HIV AND OTHER INFECTIONS AND DISEASES

Disclosed herein are bio-nanosensor devices and methods suitable for blood assays. The bio-nanosensors are based on thickness shear mode transducer capable of transmitting a shear wave into a biofluid..

STABILIZED ULTRASOUND CONTRAST AGENT

Provided is a particle-stabilized ultrasound contrast agentn (UCA) and methods of preparing same. Also provided is a method for preparing a lyoprotected UCA, a freeze-dried lyoprotected UCA, and a rec..

MULTIMODAL LASER SPECKLE IMAGING

A system for multimodal laser speckle imaging may include a first light source positioned to emit laser light toward a target, a second light source positioned to emit light toward the target, a camer..

Wrist Mounted CPR Chest Compression Monitor

A chest compression monitor for measuring the depth of chest compressions achieved during CPR. A displacement detector produces a displacement indicative signal indicative of the displacement of the C..

OPTIMIZED MRI STRIP ARRAY DETECTORS AND APPARATUS, SYSTEMS AND METHODS RELATED THERETO

Featured is a device for NMR or MRI signals from excited nuclei as well as related apparatus, systems and methods. The device includes a strip array antenna including one or more conductor and N react..

Devices and Methods for Treatment of Gastrointestinal Disorders

An implantation device for releasably holding implantable microstimulators can be used to guide one or more microstimulators to any site within the gastrointestinal tract for implantation. The device ..

SYSTEMS AND METHODS FOR TESTING VESTIBULAR AND OCULOMOTOR FUNCTION

The invention relates to systems and methods for testing vestibular and oculomotor function. One aspect of the invention provides a vestibular and oculomotor function testing device including a track ..

AUTOMATED SURFACE-BASED ANATOMICAL ANALYSIS BASED ON ATLAS-BASED SEGMENTATION OF MEDICAL IMAGING

A non-invasive imaging system, including: a non-invasive imaging scanner; a signal processing unit in communication with the imaging scanner to receive an imaging signal from a subject under observati..

VISUAL TRACKING AND ANNOTATION OF CLINICALLY IMPORTANT ANATOMICAL LANDMARKS FOR SURGICAL INTERVENTIONS

A visual tracking and annotation system for surgical intervention includes an image acquisition and display system arranged to obtain image streams of a surgical region of interest and of a surgical i..

SYSTEMS AND METHODS TO REDUCE POWER DEPOSITION IN TISSUE EXPOSED TO RADIO -FREQUENCY ELECTROMAGNETIC FIELDS

An apparatus for exposing a region of interest of an object, animal or person to an alternating magnetic field has a source of radio-frequency electromagnetic radiation arranged to provide the alterna..

Surgical Instrument and Systems with Integrated Optical Sensor

A surgical instrument has a surgical tool that has a proximal end and a distal end, and an optical sensor that has at least a portion attached to the surgical tool. The surgical tool has a portion tha..

LOW-COST IMAGE-GUIDED NAVIGATION AND INTERVENTION SYSTEMS USING COOPERATIVE SETS OF LOCAL SENSORS

An augmentation device for an imaging system has a bracket structured to be attachable to an imaging component, and a projector attached to the bracket. The projector is arranged and configured to pro..

ADIABATIC MULTI-BAND RF PULSES FOR SELECTIVE SIGNAL SUPPRESSION IN MAGNETIC RESONANCE IMAGING

A magnetic resonance imaging (MRI) system, comprising: a magnetic resonance imaging scanner comprising: a main magnet providing a substantially uniform main magnetic field B0 for a subject under obser..

IODINATED POLYMERS

The invention provides medical devices that comprise an iodinated polymer and that can be viewed using X-Ray imaging techniques. The invention also provides novel iodinated polymers that can be incorp..

METHOD FOR DETERMINING THE QUALITY OF HEPARIN

The invention relates to a method for determining contamination of heparin with other sulfated glycans, comprising the steps: incubating a predetermined amount of heparin together with a predetermined..

IMAGE-BASED RISK SCORE-A PROGNOSTIC PREDICTOR OF SURVIVAL AND OUTCOME FROM DIGITAL HISTOPATHOLOGY

The present invention relates to an image-based computer-aided prognosis (CAP) system and method that seeks to replicate the prognostic power of molecular assays in histopathology and pathological pro..

RADIOPAQUE POLYMERIC STENTS

The present invention relates to polymeric medical devices such as stents. More particularly the polymeric compositions disclosed herein comprise halogen-containing, tyrosine-derived diphenols, option..

BIOCOMPATIBLE POLYMERS FOR MEDIAL DEVICES

The present invention relates to new classes of monomeric compounds, which may be polymerized to form novel biodegradable and bioresorble polymers and copolymers. These polymers and co-polymers, while..

COMPLIANT BIOCOMPATIBLE POLYMER COMPOSITIONS FOR MEDICAL USES

Phase-separated elastomeric biocompatible polymer compositions are disclosed that are bioresorbable and/or biodegradable, and are useful in a variety of medical applications in which a low modulus pol..

BIOCOMPATIBLE POLYMERS FOR MEDICAL DEVICES

The present invention relates to new classes of monomeric compounds, which may be polymerized to form novel biodegradable and bioresorble polymers and co-polymers. These polymers and co-polymers, whil..

MULTI-USER SMARTGLOVE FOR VIRTUAL ENVIRONMENT-BASED REHABILITATION

A low-cost, virtual environment, rehabilitation system and a glove input device for patients suffering from stroke or other neurological impairments for independent, in-home use, to improve upper extr..

VARIABLE RESISTANCE HAND REHABILITATION DEVICE WITH LINEAR SMART FLUID DAMPER AND DYNOMETER CAPABILITIES

A variable resistance hand rehabilitation device and corresponding system. Improvements over the prior art include: a new damping system or damper design, to reduce friction and increase maximum force..

PATIENT SPECIFIC ANKLE-FOOT ORTHOTIC DEVICE

The unique advantages of computer-controlled fabrication of a patient-specific orthotic device using an automated fabrication machine capable of following computer instructions to create 3D surface co..

Apparatus And Method For Modulating Neurochemical Levels In the Brain

A treatment for Parkinson's Disease uses a stimulus electrode implanted in a subthalamic nucleus with a chemosensor implanted in a globus pallidus pars interna (GPi) of the subject. A level of a neuro..

SYSTEM AND METHOD FOR CALIBRATION FOR IMAGE-GUIDED SURGERY

A method of calibrating a transformation of ultrasound data in an imaging system from a first coordinate system into a second coordinate system, the method comprising applying a transformation having ..

ELECTRICAL IMPEDANCE SENSING BIOPSY SAMPLING DEVICE AND METHOD

A biopsy sampling device has an inner trocar having a sharpened tip and a sampling opening. The trocar is slideably engaged in a central cavity of an outer needle with its sharpened tip and sampling o..

Systems And Methods For Combined Ultrasound And Electrical Impedance Imaging

A dual imaging probe 300 for obtaining both ultrasound and electrical impedance data is disclosed along with methods of using the dual imaging probe 300 to interrogate tissue. An electrical impedance ..

ELECTROENCEPHALOGRAPHY MONITORING DEVICE HAVING A SELF-ADAPTIVE ANALOG-TO-DIGITAL CONVERTER

An EEG monitoring device, contains at least one electrode, a non-linear analog signal processor, a variable resolution analog-to-digital converter, a storage, and a power source. The non-linear analog..

Biological Particle Collector, and Methods of Use Thereof

One aspect of the invention relates to the devices and methods for the collection of bioaerosols (such as viruses, bacteria, and proteins) from the exhaled breath of humans and/or animals, for the pur..

Organometallic-Polyisomonoolefin Block Copolymers

The present invention provides copolymers which include a plurality of constitutional units that correspond to at least one cationically polymerizable isomonoolefin species and a plurality of constitu..

CERAMIC/STRUCTURAL PROTEIN COMPOSITES AND METHOD OF PREPARATION THEREOF

Ceramic/structural protein composites and methods of preparation are disclosed, including coatings and films. Ceramic/structural protein coatings can be fabricated on the surface of substrates, includ..

SHAPE MEMORY MAIN-CHAIN SMECTIC-C ELASTOMERS

Shape memory main-chain smectic-C elastomers are described, as are methods for their preparation and monomers used in such methods. The elastomers are prepared by hydrosilylation of a reaction mixture..

IMPLANTABLE MEDICAL DEVICES

A medical device includes a balloon catheter having an expandable member, e.g., an inflatable balloon, at its distal end and a stent or other endoprosthesis. The stent is, for example, an apertured tu..

BLENDS OF AMORPHOUS AND SEMICRYSTALLINE POLYMERS HAVING SHAPE MEMORY PROPERTIES

Blends of amorphous and semicrystalline polymers having shape memory properties were prepared by blending a crystalline polymer such as poly(vinylidene fluoride), polylactide, poly(hydroxxybutyrate), ..

METHODS AND SYSTEM FOR CONFOCAL LIGHT SCATTERING SPECTROSCOPIC IMAGING

The present invention is generally directed to imaging methods and apparatus that employ angular and/or wavelength distribution of light backscattered from multiple portions of a sample in response to..

APPARATUS AND METHOD OF ANALYZING ARTERIAL PLAQUE

A method of identifying arterial plaque analyzes arterial plaque using one or more non-invasive tests to determine if the plaque has any of a plurality of hallmarks that are predictive of disruption. ..

LABELED SKIN LESION BIOPSY PUNCH AND USES THEREOF

The present invention relates to a biopsy device, methods, kits and systems for marking the location of a biopsy site in order to later identify the location of a biopsy or surgery in a subject, where..

BIOLOGICAL CIRCUIT CHEMOTACTIC CONVERTERS

Described herein are novel biological circuit chemotactic converter that utilize modular components, such as genetic toggle switches and single invertase memory modules (SIMMs), for detecting and conv..

BIOLOGICAL ANALOG-TO-DIGITAL AND DIGITAL-TO-ANALOG CONVERTER SWITCHES

Described herein are novel biological converter switches that utilize modular components, such as genetic toggle switches and single invertase memory modules (SIMMs), for converting analog inputs to d..

Fully automated control system for type 1 diabetes

An augmented, adaptive algorithm utilizing model predictive control (MPC) is developed for closed-loop glucose control in type 1 diabetes. A linear empirical input-output subject model is used with an..

LOW COST DISPOSABLE MEDICAL FORCEPS TO ENABLE A HOLLOW CENTRAL CHANNEL FOR VARIOUS FUNCTIONALITIES

The present invention relates to an endoscopic biopsy forceps (10) with an open central channel. The forceps include a sheath (20) having a proximal end and a distal end, a housing (50) connected with..

Dermal punch device

A dermal punch for extracting skin or tissue samples. The dermal punch has a blade having a pair of walls. Each wall is convex and opens towards each other. The walls are connected to each other at a ..

BONE FIXTURE ASSEMBLY

An assembly for rigid bone fixation includes a plate and a screw. The screw can be rotated freely within the plate in a non not locking configuration to secure the plate against the bone. A locking me..

MODULAR THERAPEUTIC PRESSURE APPLICATION DEVICES

The invention relates in some aspects to therapeutic pressure application devices and methods of manufacturing and using the same. In some aspects, the devices comprise a support structure shaped to c..

SPECTROSCOPIC SENSORS

Disclosed herein are sensors that include: (a) a circuit board that includes an electronic processor; (b) a plurality of radiation sources, each source being attached to the circuit board; and (c) a s..

SUSPENSION/RETRACTION DEVICE FOR SURGICAL MANIPULATION

A device that can be delivered into a body cavity to manipulate tissue intracorporeally while being controlled extracorporeally and a method of using the device to perform a single-port laparoscopic o..

INTRAUTERINE FALLOPIAN TUBE OCCLUSION DEVICE

An intrauterine device for occluding orifices of fallopian tubes includes a resilient body having an elongated member with a first end and a second end. The elongated member further includes a first l..

PARALLEL MAGNETIC RESONANCE IMAGING USING NONLINEAR GRADIENT ENCODING

In MRI by excitation of nuclear spins and measurement of RF signals induced by these spins in the presence of spatially-varying encoding magnetic fields, signal localization is performed through recom..

VOLUME STATUS MONITOR: PERIPHERAL VENOUS PRESSURE, HYPERVOLEMIA AND COHERENCE ANALYSIS

Systems and methods are provided for monitoring changes in blood volume using waveforms in the peripheral vasculature. In particular, the systems and methods relate to detecting ventilation-induced va..

Dynamic spine stabilizer

A dynamic spine stabilization device is provided that includes at least one force imparting member, e.g., a spring. The force imparting member is adapted to deliver a force of between about 150 lb/inc..

Method of Assessing Blood Volume Using Photoelectric Plethysmography

A method and system for assessing blood volume within a subject includes generating a cardiovascular waveform representing physiological characteristics of a subject and determining blood volume of th..

Bone Implant Device and Methods of Using Same

A bone implant device comprising a plurality of interconnected plate members, at least one plate member defining a plurality of apertures therein adapted for permitting bone growth there through from ..

ACCESS DEVICE

A device may include a hollow needle, a dilator mounted coaxially on the needle, and a sheath mounted coaxially on the dilator. The dilator may be slideably displaceable relative to the sheath.

METHOD FOR IMPLANTING INTRAOCULAR PRESSURE SENSOR

Methods of implanting an intraocular pressure sensor and systems tbr sensing intraocular pressure are disclosed. An intraocular pressure sensor, including, a top surface, may be placed through the scl..

UVEOSCLERAL DRAINAGE DEVICE

An ophthalmic shunt implantable in an eye having an elongate body (10) and a branched conduit (40) for conducting aqueous humor from an anterior chamber of the eye to the suprachoroidal space of the e..

DEVICE FOR MEASURING AND ANALYSING THE COLOUR OF THE OUTER EAR AND EAR CANAL

The present invention concerns a device for measurement and analysis of the middle ear and ear channel colour. This device allows thus automatic patient middle ear colour measurement and intends to be..

SUPRAPUBIC INSTRUMENT USED SPECIFICALLY IN ENDOSCOPIC PROSTATE SURGERY

The invention relates to a single tool that complements the technique performed by a resectoscope (4), which combines puncturing and subsequently extracting the irrigation liquid and remains of the ex..

MAGNETIC HYPERTHERMIA APPLICATION DEVICE

Magnetic hyperthermia application device (1) to apply magnetic hyperthermia treatment to a sample, characterized as such because it includes: an LC resonant tank (3), consisting of a first coil (5) an..

DEVICE FOR CLAMPING SAMPLES IN MECHANICAL TESTS ON SOFT TISSUE

The invention relates to a jaw-type device that can be used to clamp soft tissue samples, such as biological tissue, in order for traction tests to be performed on said tissues. The device can also be..

MICRO-STEREOSCOPIC RETINAL PHOTOGRAPHY METHOD

The invention relates to a micro-stereoscopic retinal photography method, characterised in that said method uses a combination of two axes, X and Y, manipulating the moving parts of a retinal scanner ..

DEVICE FOR APPLYING A CONTACT ANAESTHETIC

Device for applying a contact anaesthetic, such as those used mainly in superficial ophthalmological surgery for application of a local anaesthetic, characterized in that it consists of a porous strip..

FORENSIC IDENTIFICATION SYSTEM USING CRANIOFACIAL SUPERIMPOSITION BASED ON SOFT COMPUTING

The invention relates to a method and an automatic system for assisting a forensic anthropologist in the task of identification by means of craniofacial superimposition. First, the system automaticall..

PORTABLE DEVICE FOR SELF-VIEWING BLOOD CELLS IN THE RETINA

The invention relates to a compact, portable instrument that is easy to use, enabling the patient to evaluate him/herself in a few seconds whether the blood circulation in his/her retina is correct, a..

DEVICE FOR THORACOSTOMY

The invention relates to a device (1) for thoracostomy, in particular for relief of a (tension) pneumothorax, comprising a cannula (2) and a needle (3) slidingly sheathed m the cannula (2). A spring (..

MICRONEEDLE INJECTING APPARATUS

A method of delivering a microneedle array to a substrate including the steps of propelling the microneedle array towards the substrate utilising a microneedle applicator device which propels the micr..

TOOLS FOR USE IN TREATMENT OF MALE URINARY INCONTINENCE.

A transobturator technique was developed for treating male urinary incontinence. This approach helped to design specific instruments to pass around the ischio-pubic branches of the male pelvis from in..

DEVICES FOR SURGICAL TREATMENT OF FEMALE URINARY INCONTINENCE

A variety of specifically designed surgical instruments to perform a new, quick, simple, efficient, safe, and reproductible surgical technique for the treatment of female urinary incontinence, in whic..

A method and device for processing and presenting medical images

The present invention relates to a method for processing and presenting at least a first image and a second image, these images being digital medical images. A first step in the method is performing i..

METHODS AND SYSTEMS FOR ANALYSING RESUSCITATION

A system (100) for analysing resuscitation is described. The system comprises an input means (120) for obtaining a plurality of pressure values over time. It also comprises a tracheal pressure value p..

GDF15 AS MOLECULAR TOOL TO MONITOR AND ENHANCE PHENOTYPIC STABILITY OF ARTICULAR CHONDROCYTES.

The present invention relates to GDF15 as a molecular marker in in vitro assays determining phenotypic stability of articular chondrocytes and predicting the outcome of chondrocyte transplantation.

IMPLANTABLE SENSOR

A sensor is described for sensing a substance such as for example glucose. The sensor is implantable in the body of a living creature. The sensor comprises a photonic integrated circuit, e.g. silicon-..

COCHLEAR IMPLANT APPARATUS

The invention relates to cochlear implants and to improved methods of operating such implants. We describe cochlear implant apparatus comprising an audio signal processing unit with a wired or wireles..

Active Interface Device

An active interface device including a transducer or sensor array having a plurality of transducers or sensors arranged to transform a cell activity into an electrical signal, at least one detection u..

Large Time Constant Steering Circuit and Instrumentation Amplifier Implementing Same

The present invention relates to a large time constant steering circuit for slowly changing a voltage on a node between at least two discrete voltage levels. The present invention further relates to a..

FLEXIBLE ENDOSCOPE DEVICE WITH VISUAL CONTROL AND PROCESS FOR STABILIZATION OF SUCH A DEVICE

A flexible endoscope device includes an elongated flexible body having an end segment bearing or defining the endoscope head, and provided with an optical system that can be curved or bent in at least..

ADJUSTABLE CATHETER OR ENDOSCOPE STRUCTURE

The structure e.g. catheter (27), has a resiliently deformable longitudinal body (28) including a memory shaped actuator e.g. yarn (38), integrated longitudinal to the body that is in the form of an e..

SURGICAL INSTRUMENT

The invention relates to a surgical instrument (1) comprising: an elongated arm (11; 307) according to a longitudinal axis and having a distal end (2; 305) mounted with a pivot joint on the elongated ..

DEVICE FOR MEASURING THE ACTIVITY OF THE SPINAL CORD OF A VERTEBRA

The invention relates to a device for measuring the activity of the spinal cord of a vertebra, characterized in that the device comprises at least one main probe (1) shaped so as to be attached to a s..

Assay device and method for chemical or biological screening

An assay device (1) comprises a base (2) and glass plate lid (3). The base (2) has an array of shallow microwells (4), each having a flat rim (9), all rims being co-planar. When the lid (3) is placed ..

A device for treating tissue

An apparatus for use in carrying out a prophylactic or treatment procedure on tissue comprises a head piece 1 having a receiver 2 for receiving an instrument such as an endoscope 10 and a chamber 3 in..

A stent delivery system

A stent delivery balloon 1 is used to deploy a plurality of mini-stents 5 into a bodily lumen at a controlled spacing. The balloon 1 has formations 3 for retaining the stents in a designed position. T..

ENDOSCOPY SYSTEM WITH MOTION SENSORS

An endoscopy system (1) comprises an endoscope (2) with a camera (3) at its tip. The endoscope extends through an endoscope guide (4) for guiding movement of the endoscope and for measurement of its m..

INTRAVASCULATURE DEVICES AND BALLOONS FOR USE THEREWITH

An inflatable device (1) for use within the vasculature of a body and having an expandable annular body (Ia) which is expandable by inflation of a series of inflation lumen (2) defined therein, the de..

Method and apparatus for imaging tissue topography

The present invention related to an optical device for imaging and measuring characteristics of an objects surface shape, surface spectral reflectance and structure of sub-surface layers. In particula..

METHOD AND SYSTEM FOR MONITORING SLEEP

A method of monitoring sleep comprises simultaneously recording a person's electrocardiogram (ECG) and photoplethysmogram (PPG), deriving a plurality of parameters from the recorded data, and providin..

A LATERAL FLOW ASSAY DEVICE FOR COAGULATION MONITORING AND METHOD THEREOF

The present invention is directed to a lateral flow assay device for the monitoring and measuring of coagulation and method thereof. Ideally, the invention is directed to a lateral capillary flow devi..

VESSEL SUPPORT DEVICE AND METHODS FOR SUPPORTING A VESSEL

The present invention is directed to a vessel support member having opposing ends adapted to move in a circumferential plane, the support member configured for deployment in a substantially radial dir..

ORTHOPAEDIC DEVICE FOR THE TREATMENT OF SPINAL DISC DEGENERATION DISEASE

An orthopaedic device is provided for the treatment of spinal disc degeneration disease (DDD). The device comprises a vertebral body spacer capable of being placed between a first vertebral body and a..

METHOD, SYSTEM AND APPARATUS FOR VENTILATION

The invention relates to a ventilator for delivering fluid pressure to the lungs of a subject, the ventilator having; a pump in operative connection with a first pressure vessel for control of the pea..

RESPIRATORY AID DEVICE

A system is described for stimulating the chest wall of a subject to reduce breathlessness. The system includes a respiration sensor (3) operable to generate an output signal dependent on respiration ..

A WIRELESS CODE GAME ENURESIS ALARM FOR THE TREATMENT OF ENURESIS

A system (10) and method for use by a subject with a sleep disorder, such as nocturnal enuresis. The system (10) comprises at least one sensor (11) that detects at least one attribute of the sleep dis..

Pressure sensor for measuring intraocular pressure that can be worn on the eye.

A pressure sensor that can be worn on the eye of the user for measuring the intraocular pressure of the user. The pressure sensor may take the form of a strain gauge 24 which has a resistance element...

PHASE LOCK EVOKED RESPONSE AUDIOMETER

An evoked response audiometer method and apparatus in which a patient receives an auditory stimulus signal comprising a carrier frequency which is periodically amplitude modulated and frequency modula..

METHOD AND APPARATUS FOR SENSORY FIELD ASSESSMENT

A method for assessing the function of at least one sensory field of a subject, and apparatus and systems for carrying out the method, the method comprising: using a display, presenting stimuli to sel..

NEURAL CIRCUITS AND STEREOTACTIC APPARATUS

Herein are disclosed: - solid or semi-solid implantable neural circuits conduit comprising an elongate polymer sheath and one or a plurality of neurons in the lumen of the sheath or embedded in the sc..

DEVICES AND METHODS FOR DETECTING ss-HAEMATIN AND HAEMOZOIN

In the application, the change in the magnetic state of the haemoglobin caused by the malarial infection is exploited by detecting suitable properties of haemozoin which are dependent on the applicati..

MICROFLUIDIC APPARATUS AND METHOD FOR DNA EXTRACTION, AMPLIFICATION AND ANALYSIS

An integrated gel based microfluidic sample processing device An integrated gel based microfluidic sample processing device, suitable for forensic investigations at the scene of a crime,comprising a s..

Speech valve

The valve 10 comprises a generally cylindrical body 12, 14, 16 and a closure member 62 which is slidably movable within the body between a closed position and an open position. The valve body and the ..

A SPEECH VALVE, A TOOL FOR FACILITATING INSERTION OF A SPEECH VALVE AND A TOOL FOR HOLDING A SPEECH VALVE

A tool (106) for facilitating insertion of a speech valve (10) with a flexible retention flange (56) into a fistula between the trachea and the oesophagus of a human patient, having a wall (108) curve..

DEVICE FOR MEASURING SPINAL CURVATURE

The invention relates to a non-invasive device and method for measuring spinal curvature. Apparatus shown in Figure 1 includes a wheeled member rotatably mounted on a handle, which in use is moved alo..

SURGICAL MANIPULATOR

Surgical Manipulator A surgical manipulator (10) is disclosed which employs a suction cup (30) to hold body parts (50) whilst the manipulator is moved to manipulate the body part (50). Suction at the ..

INFLATABLE PRESSURISED MEDICAL CHAMBER FOR USE IN BLOODLESS SURGERY

The invention relates to a device for performing substantially bloodless surgery wherein the device comprises a double-skinned chamber 3, 4 with at least one through-bore 5. A pressurized gas supply i..

MEDICAL FLUID COMMUNICATION COUPLINGS

A medical coupling system is disclosed for coupling medical apparatus in fluid communication, the system comprising a plurality of groups of couplings, each member (10) of each group including first (..

PULSATILE BLOOD PUMP

There is provided a pulsatile blood pump (10) for implantation into a patient. The pulsatile blood pump comprises a substantially tubular body (12) a flexible membrane (14) and a port (16). The substa..

ROTARY BLOOD PUMP

There is described a rotary blood pump comprising a rotor and a stator which houses the rotor. The rotor defines an axis of rotation. The rotor has a rotor hydrodynamic bearing surface and rotor beari..

TRANSPEDICULAR ACCESS TO THE INTERVERTEBRAL DISC SPACE FOR DISCECTOMY, END PLATE PREPARATION, AND INTERBODY FUSION

An insertion device is configured to access a disc positioned between adjacent vertebrae. The insertion device includes a cannula having a passage formed therein. The cannula has an exit aperture. An ..

INSERTION ASSEMBLY FOR MINIMALLY INVASIVE SPINAL SURGERY

A telescopic insertion assembly is configured to insert a pedicle screw into a vertebral body. The insertion assembly includes an attachment fixture having one end configured to mate with the pedicle ..

PEDICLE SCREW ASSEMBLY HAVING A RETRACTABLE SCREW TIP FOR FACILITATING THE SECUREMENT OF THE PEDICLE SCREW ASSEMBLY TO A SPINAL VERTEBRA

A pedicle screw assembly has a retractable screw tip that facilitates the securement of the pedicle screw assembly to a spinal vertebra in a minimally invasive fashion during an orthopedic surgical pr..

FIXATION ASSEMBLY HAVING AN EXPANDABLE INSERT

A fixation assembly having one or more insertions member that include one or more expandable and retractable anchoring inserts positioned along at least a portion of the insertion member and methods o..

DIRECTIONAL SOFT TISSUE DILATOR AND DOCKING PIN WITH INTEGRATED LIGHT SOURCE FOR OPTIMIZATION OF RETRACTOR PLACEMENT IN MINIMALLY INVASIVE SPINE SURGERY

A soft tissue dilator for use in a surgical procedure includes a first dilator member that defines a first axis and a second dilator member that defines a second axis. The second dilator member is sup..

PEDICLE SCREW ASSEMBLY HAVING A RETRACTABLE SCREW TIP FOR FACILITATING THE SECUREMENT OF THE PEDICLE SCREW ASSEMBLY TO A SPINAL VERTEBRA

NEEDLE FOR DIRECTIONAL CONTROL OF THE INJECTION OF BONE CEMENT INTO A VERTEBRAL COMPRESSION FRACTURE

A needle for use in a surgical procedure includes an outer cannula including a shaft portion having a side wall and an end wall. A first aperture extends through the side wall of the outer cannula, an..

STERILIZATION OF MEDICAL DEVICES USING EXPANDED ORGANIC ACIDS

The present invention concerns a process for sterilizing biomedical devices using organic acids expanded by compressed gases to form an "expanded liquid". The term "expanded liquid" means, in the tech..

AIR CUSHION SENSOR FOR TACTILE SENSING DURING MINIMALLY INVASIVE SURGERY

A sensor is described for detecting the force applied to or by soft material, and that is thus able to measure the stiffness of a soft material. The sensor comprises a sensor body into which is suppli..

APPARATUS AND METHOD FOR MEASURING BLOOD PRESSURE

The application relates to an apparatus and a method for estimating a central systolic blood pressure (cSBP) of a subject, in which a peripheral blood pressure waveform of the subject's pulse and at l..

CMYBP-C AND MLC2 AS DIAGNOSTIC MARKERS OF CARDIAC INJURY

The invention relates to markers for acute myocardial infarction (AMI), particularly markers that may be used in the rapid and accurate diagnosis of AMI or reinfarction. A method of diagnosing cardiac..

REVERSIBLY GELLING POLYURETHANE COMPOSITION FOR SURGICAL REPAIR AND AUGMENTATION

A new reversibly gelling polyurethane (RGP) polymer composition is described, as well as novel processes for its preparation, and its medical uses for filling spaces in tissue, or bulking tissue, or f..

BIOACTIVE MATERIAL DELIVERY SYSTEMS COMPRISING SOL-GEL COMPOSITIONS

Implantable medical devices employing a sol-gel composition coatings that functions as a bioactive material reservoir, and the use of sol-gel composition coatings for improved adhesion of organic and ..

MEDICAL TUBING SECUREMENT ASSEMBLY AND METHODS OF USE

A medical tubing securement assembly includes a base having a disc, and a retaining adapter removably and rotatably attached to the disc. The retaining adapter includes a longitudinal passage for rece..

UNIVERSAL CATHETER SECUREMENT DEVICE

A universal securing device for holding catheters of various shapes and sizes and the like in place includes a base and cover. The cover may be connected to the base by a hinge which allows the cover ..

A DEVICE FOR DELIVERING MEDICAL TREATMENT

he present invention provides a medical device for the delivery of treatment fluid to body vessels, having a distal (21) and a proximal (20) end, comprising a self-expanding, hollow tubular member (9)..

METHODS AND DEVICES FOR CONTINUOUS SUTURE PASSING

Described herein are suture passers for suturing tissue in a continuous manner by passing a suture attached to a suture shuttle through. A suture passer may include a first jaw, a second jaw, and a ti..

AMBULATORY AID WITH A POWER UNIT

A device comprising an ambulatory aid, the device comprising a distal end, a load, a first portion positioned at, or close to the distal end and adapted to allow the device to move along a surface, a ..

TARGET ACQUISITION SYSTEM

A targeting system and method for remotely controlling the zoom and pan features of a device for display in an operating room is provided. The invention generally relates to a system and method for..

STENT DELIVERY DEVICES, SYSTEMS & METHODS

The present invention relates to devices, systems and methods to maintain self- expanding stents in a compressed form during delivery and positioning at a treatment site. Such a device may comprise a ..

IMPLANTABLE AND LUMEN-SUPPORTING STENTS AND RELATED METHODS OF MANUFACTURE AND USE

An implantable stent includes multiple circumferential segments that surround a bore and are connected in series along a length to form a tubular wall. Multiple adjacent alternating opposite facing cr..

SUTURE PASSING INSTRUMENT AND METHOD

A continuous suture passer device (10) may include a first jaw (20) and a second jaw (21 ); an actuator (15) including a jaw control which may manipulate at least one jaw; a tissue penetrator (50) whi..

SURGICAL ANTENNA

A surgical instrument (100) (e.g. scalpel) is disclosed which has an antenna arranged to emit a substantially uniform microwave radiation field (e.g. having a frequency of 5-100 GHz) at an edge of a c..

NEEDLE STRUCTURE AND METHOD OF PERFORMING NEEDLE BIOPSIES

A biopsy needle (80) having a longitudinal channel (84) formed within an inner conductor (86) of a coaxial antenna is disclosed. The coaxial antenna terminates in a rigid insertion tip (82) e.g. a cer..

MEDICAL DEVICES, APPARATUSES, SYSTEMS, AND METHODS

Apparatuses and systems for enabling electrical communication with a device positionable within a body cavity of a patient. Apparatuses and systems for magnetically positioning a device within a body ..

THERAPEUTIC METHODS USING CONTROLLED DELIVERY DEVICES HAVING ZERO ORDER KINETICS

An injectable or implantable medical device having orifice(s) on the surface that release an active agent with zero-order release kinetics is described herein. The device is a hollow matrix of any siz..

PHOTOKINETIC OCULAR DRUG DELIVERY METHODS AND APPARATUS

The present invention relates generally to transscleral and transocular delivery of biologically active substances through the tissues, blood vessels and cellular membranes of the eyes of patients wit..

APPARATUS FOR TREATING TISSUE WITH MICROWAVE RADIATION AND ANTENNA CALIBRATION SYSTEM AND METHOD

A calibration method and apparatus for surgical antennas which are arranged to deliver microwave radiation (e.g. having a treatment frequency of 500 MHz to 100 GHz) into biological tissue is disclosed..

OESOPHAGEAL TREATMENT APPARATUS

A probe and associated apparatus for treating oesophageal tissue with microwave radiation (e.g. radiation having a frequency of 5-60 GHz) are disclosed. The probe comprises a flexible substrate that e..

ELECTRICAL WOUND HEALING SYSTEM AND METHOD

A wound healing system comprising an array of electrodes incorporated in a device for applying an electrical signal to a wound. The electrodes are configurable to form at least one composite electrode..

SKIN MARKER

A skin marker for providing a reference point for a plurality of different medical imaging procedures, said marker incorporating one or more substances having one or more of radiance and/or hydration ..

AN INFANT INCUBATOR WITH RADIANT HEATER

An infant incubator comprises a radiant means (30) with an infrared heater (12). A infant bed (16) is provided under the radiant means (30) and includes a humidifier (7) and a second temperature contr..

HARD TISSUE REGENERATION DEVICE

PROBLEM TO BE SOLVED: To provide a new hard tissue regeneration device using osteoblast. ; SOLUTION: The hard tissue regeneration device is a complex of an osteoblast and a honeycomb porous body havin..

URINE COLLECTION DEVICE

A pad assembly for use with a urine collection device comprises an external layer (2), which is preferably an impermeable conformable material. The external layer (2) partially surrounds a filling mat..

Device for supporting at least one arm of an operating person during a surgical or medical operation

A device for supporting at least one arm of an operating person during a surgical or medical operation comprises at least one supporting element for supporting the at least one arm of the operating pe..

Heating system

A body part heating system (10) comprises a temperature sensor (28) adapted to measure the temperature of a body part, and a heater (34a, 34b) in communication with the temperature sensor (28). The he..

MAGNETIC RESONANCE IMAGING OF LABELLED CELLS

A method and apparatus for obtaining a magnetic resonance image of a sample by applying a radio frequency signal to a sample containing magnetically labelled cells or tissues in order to heat the magn..

PRESSURE MEASUREMENT DEVICE

A non-invasive device adapted to measure intraocular pressure (IOP) comprising: a pressure sensor mounted on a soft contact lens to be worn on the eye of a subject, wherein the device is adapted such ..

APPARATUS AND METHOD FOR THE MANIPULATION OF OBJECTS USING ULTRASOUND

A method and apparatus for manipulating particles. The apparatus comprising an ultrasound source for providing a variable ultrasound signal within a region of interest, and a controller connected to t..

APPARATUS AND METHOD FOR MINERALISING BIOLOGICAL MATERIALS

An apparatus and method for mineralising demineralised and hypo-mineralised biological material such as tooth or bone. The apparatus has a probe electrode for receiving a mineralisation agent and a co..

METHODS FOR REDUCING FALSE HYPOGLYCEMIA ALARM OCCURRENCE

A system and method for reducing the number of hypoglycemic alarms presented to a user is presented. The system and methods include use of model based state estimation and variable-delayed threshold v..

Valve disc and combination filling device using the valve disc, and tube, pipe jointing device, connection port manufacturing device, and pipe jointing system

A tube (51,30) including a flow path (51) in the inside, at least a part of which is constituted by a flexible material, the tube (51,30) is provided with at least one inner slit along an axis of the ..

Automatic sample collector

This invention relates to an automatic sample collector for liquids which are discharged from a chromatographic column, a dialysis apparatus, or a reaction container, for example, and are consecutivel..

MICRODIALYSIS CHAMBER SYSTEM WITH INCLUDED COLLOIDAL MATERIALS AND METHOD FOR THE MANUFACTURE THEREOF

The invention relates to a microdialysis chamber system comprising a base member (1) made of a solid material that does not swell in water, at least one cavity (4) functioning as a dialysis chamber, c..

METHOD AND SYSTEM FOR THE INTEGRAL AND DIAGNOSTIC ASSESSMENT OF LISTENING SPEECH QUALITY

A method for determining a speech quality measure of an output speech signal with respect to an input speech signal, wherein the input signal passes through a signal path of a data transmission system..

Hand-held tattooing device for bringing e.g. medical active ingredient into e.g. human skin, has drives that are coupled to cutting blade for shifting blade in multiple cutting positions along cutting

The device (1) has a cutting blade (3) that is shiftable between multiple basic positions that are assigned to respective cutting depth. A liquid supplying device supplies liquid to be brought for ent..

ANASTOMOSIS RING AND ANASTOMOSIS RING ASSEMBLY

The invention relates to an anastomosis ring and to an anastomosis ring assembly for connecting hollow organs made from human or animal tissue. The anastomosis ring includes a first support ring and a..

Polymerstent

The invention relates to a polymer stent with open ends at the longitudinal support structure which includes an interior that allows the passage flow of body fluid (eg blood) from an open longitudinal..

ULTRASONIC DIAGNOSTIC APPARATUS

PROBLEM TO BE SOLVED: To provide an improved ultrasonic diagnostic apparatus to be used for diagnosing a bone including a healthy region and a diseased region. ; SOLUTION: An ultrasonic beam 40 for ec..

BONE EXAMINATION SYSTEM

PROBLEM TO BE SOLVED: To easily position lower limbs in a bone examination system for executing an examination based on the deformation of bones by adding loads to the bones of the lower limbs. ; SOLU..

ULTRASONIC PROBE SUPPORTING DEVICE

PROBLEM TO BE SOLVED: To move an ultrasonic probe along a kneecap to obtain ultrasonic echo information for the cartilage of a knee joint. ; SOLUTION: An attaching unit 16 is positioned by an attachin..

KNEE ACOUSTIC MATCHING BOX FOR ULTRASONIC PROBE

PROBLEM TO BE SOLVED: To achieve acoustic matching between the kneecap and an ultrasonic probe when the ultrasonic probe is moved along the kneecap for obtaining ultrasonic echo information for the ca..

BLOOD-PRESSURE SENSOR SYSTEM

There is provided a blood-pressure sensor system wherein a blood-pressure sensor including a plurality of structures which induces surface plasmon resonance on a light-receiving plane of a photoelectr..

SYSTEM FOR TRANSPORTING DRUGS AND MEDICAL MATERIALS IN HOSPITAL

Provided is a system for transporting drugs and medical materials in a hospital wherein drugs and medical materials required in each ward can be mounted previously on a tray which is a unit of transpo..

Automated Vitrification System

Market Opportunity Cryopreservation of biological materials by vitrification has made significant inroads in displacing the more conventional slow-freeze process. However, technicians must conduct a..

Device for High Efficiency Cell Encapsulation using Novel On-Demand Droplet Generation and Impedance-Based Detection

Tech ID: 21236 Brief Description Researchers have developed a novel microfluidic device that is capable of encapsulating cells at a very high efficiency. The device integrates impedance measuremen..

Colloidal Self-Assembly of Droplets for High Density Microfluidic Micro-Reactor Arrays with High Throughput Functionality

Tech ID: 21274 Brief Description Researchers have developed a simple method for the rapid self-assembly of predictable high density droplet-reactor arrays for high throughput microfluidic applicat..

Microfluidic Device using Dielectrophoresis Separation of Heterogeneous Cell Populations

Tech ID: 21272 / UC Case 2011-181-0 Brief Description Researchers have developed an automated microfluidic device that traps different cell populations in different chambers based on the cells’ ..

TIO2 Nanotubes - A New Cold Cathode for X-Ray Generation

Tech ID: 20909 Brief Description Researchers have shown that titanium dioxide (TiO2) nanotubes (NT) may be used as a cold cathode X-ray source. Full Description Researchers have shown that tit..

A Removal Esophageal Stent

Tech ID: 20908 Brief Description Physicians have developed a new esophageal stent that can be easily removed. Suggested uses This stent may be used to prevent or treat gastrointestinal leaks...

Hydrostatic Pressure Pump and its use in Valving for Centrifugal Microfluidics

BRIEF DESCRIPTION Researchers have developed a hydrostatic pressure pump for centrifugal microfluidic applications. FULL DESCRIPTION In centrifugal microfluidics, the hydrostatic pressure pump ..

Portable Ultrasound Bladder Monitor

“Proactive Bladder Health” through a wearable, non-invasive device for wireless monitoring of bladder volume. • Non-invasive operation ideal for systematic use, e.g. every night or all day �..

Portable, Foldable Mirror

The present invention relates generally to mirrors and, more specifically, to a portable mirror having a plurality of foldable mirror panels, each hingedly attached to a main mirror panel. A light fix..

Digital Staining for Histopathology

Background 99.9 % of cancer cases are diagnosed and monitored by histopathological assessment of a biopsy sample. The presence, concentration and distribution of biological molecules (such as nuclei..

Confocal Microscope with 2-D Array of LEDs

Background Confocal microscopes can provide 3-dimensional (3D) images with superior contrast and depth resolution compared to conventional wide-field microscopy because they reject the out-of-focus ..

C-Pap Face Protector

A comfortable, moisture absorbant barrier between the face and the plastic of the c-pap mask. Helps to eliminate discomfort of sweating around the nose & mouth as well as helping to control skin probl..

Magnetic apparatus for the treatment of cataracts and other eye conditions

Cataract is the leading cause of blindness in the world today. More than 160 million people have visual impairment, with three quarters of the cases related to cataracts. Sixty per cent of world bli..

Portable Imperial College Surgical Assessment Device (pICSAD)

Background Dexterity is a crucial aspect of surgical competence. Technical ability to perform a procedure is considered to be crucial for a safe and effective outcome and is also an important aspec..

Sutureless Chest Drain Dressing

Background Air or blood in the pleural cavity is a serious condition which can become life threatening. World-wide, it is estimated that 5 million chest drains are inserted annually. Currently, ch..

Improved Tunneling Catheter

Annually, approximately 100,000 US patients suffer end stage renal disease and commence renal dialysis (1). All of these patients require an AV access. Over 70% of patients initiating chronic haemodia..

Post-Stroke Neuro-Rehabilitation Device

Stroke is one of the leading causes of adult disability in the world, with more than 15 million cases every year. Most stroke survivors suffer from hemiparesis, a paralysis of one side of the body, r..

Improved Endoscope

Current endoscopes fall into the categories of rigid optical endoscopes, flexible video endoscopes and flexible optical endoscopes. Rigid endoscopes are typically used in orthopaedic surgery or surge..

Oblique Selected Plane Microscopy For Optically Sectioned Imaging

Conventional optical microscopy provides high resolution images and has a huge range of applications. In many cases, it is desirable to obtain so-called ‘optically sectioned’ images, i.e. an imag..

Novel Doppler Method

Recent advances have demonstrated the feasibility of molecular imaging using targeted microbubbles and ultrasound. However, one technical challenge is to selectively detect targeted bubbles from those..

A Novel Attenuation Correction Technique for Ultrasound Contrast Agent Imaging

Quantification of tissue perfusion using ultrasound and contrast agents has great potential for various clinical conditions which involve changes of blood flow in tissue, e.g. tumours or myocardial in..

Active Mobilization Shoulder Brace

Many types of shoulder injuries can be treated by positioning the arm in abduction (elevated sideways) and external rotation (twisting the arm outwards). This results in an extremely uncomfortable pos..

Modular Partial Knee Replacements

There is growing demand for surgical procedures to remedy pain caused by early stage arthritis in the knee, but due to physical wear and osteolysis, implants are not expected to last a patient’s lif..

Hip Resurfacing Implants

In 2008, there were 378,865 hip replacement procedures in the US alone and the number of procedures is predicted to increase with a CAGR of 5.1 % from 2008 to 20151. All hip replacements currently ar..

Low Level Laser battery operated medical devise

Medical Device: A low level hand held battery operated medical laser device has been developed and clinically tried with proven good results on almost all medical conditions encountered in a medica..

Device to Monitor Cardiac Tissue Viability

DESCRIPTION: The last decade of cardiac surgery has witnessed significant strides towards better understanding and management of previously lethal cardiac pathologies. It is now recognized that condit..

Platform for Chemical and Biological Sensing by Surface Enhanced Raman Spectroscopy

BACKGROUND: Surface-Enhanced Raman Spectroscopy (SERS) is an optical analysis technique that can provide molecular identification and quantification by recording a spectrum that displays characterist..

Epidermal Marking Pen for use in Surgical Marking and Cosmetics

The current use of surgical marking pens in the operating theater is quite common. However, these pens suffer from many drawbacks. These pens smear and despite the thinness of their tip, the ink spre..

Novel Microneedle and Micro-Blade Fabrication Technique for Biomedical Applications

This invention presents a novel needle fabrication technique for creating a sharp, beveled metallic microneedle. Using a SU-8 mold structure, needle tip geometry with beveled dimensions can be control..

Wheelchair Advantage Mobility System (WAMS)

WAMS is a bolt-on system with hand-actuated levers and disc/caliper system to propel, brake and securely park a manual wheelchair. It incorporates a set of ergonomic handles that enables users with r..

Releasable Safety Mechanism for Prosthetic Implants

Prosthetic implants for amputees contain a metal post surgically implanted into the bone that protrudes through the skin. Any torsional or bending force applied to the prosthetic may fracture the bon..

Antimicrobial Contaminant Cap for Prosthetic Implants

This novel technology describes an antimicrobial contaminant cap for preventing infection at the implant-tissue interface for prosthetic implants. The cap is designed to slide along the pin, tube, po..

Occipital-Cervical Plate for Spinal Fixation

Fixation of the skull to the cervical spine may be used to treat trauma to the neck, degenerative diseases such as rheumatoid arthritis, and congenital instability. Many current implantable devices d..

Disposable Fluid Sensor

This technology is useful for determining the level of fluid in a container. An indicator such as a flashing light or an audible alarm is used to indicate when the fluid level in a container drops bel..

Physiologically Motivated Control for Blood Pumps

Heart failure is one of the leading causes of death in America. Currently 4.7 million Americans suffer from congestive heart failure in different stages, with 954,000 people dying every year from som..

Surgical Electric Blade Coated With Quasicrystalline Twin Films

Medical surgery is performed in all countries of the world ranging from very simple procedures involving flesh and bones in hands to very complex procedures on the brain. It is desirable to use surgic..

Catheter Tracking with Phase Information

Background Currently invasive cardiovascular procedures rely on x-ray angiography to navigate a cardiac catheter to a location of interest. Interventional cardiology would benefit from using MR gui..

Sampling and Toxicity Device

Aquatic and gaseous environments are often contaminated by a wide range of toxic chemicals. Monitoring of contamination requires the use of sampling and test methods that need to be selected based on..

The TeleWatch Patient Monitoring System

The Johns Hopkins Medical Institutions, Division of Cardiology and The Johns Hopkins Applied Physics Laboratory have developed medical procedures and associated telehealth system capabilities for the ..

An Unclad Fiber Optic Sensor for Measuring Chromophoric Compounds in Human Blood and Amniotic Fluid

Yellow or brown tinged skin and eyes are the hallmarks of jaundice – seen most often in infants. The yellowing is a result of elevated levels of a substance called bilirubin in the blood (hyperbilir..

Combined Chemical/Biological Agent Detection by Mass Spectrometry

Small devices that can rapidly and accurately analyze chemical and biological molecules are required by many industries. Homeland security and the medical community lead the list. Current instruments ..

Remote Monitoring and Relaying for Wrist Watch Alarm

Hearing loss can be a problem for many segments of the population. As the population gets older and the ability to hear high pitch sounds decreases, it may not always be possible to hear a watch alarm..

Helmet System Including at Least Three Accelerometers and Mass Memory and Method for Recording in Real-Time Orthogonal Acceleration Data of a Head

Conventional devices which measure acceleration in a single direction, or from a single event, or only above a predetermined threshold, or in a way which does not permit use during performance of the ..

Instrumented Model of the Human Torso for Ballistic Impact

Effective body armor minimizes injury by transferring the kinetic energy of a projectile over an extended time-scale or surface area. Body armor that accomplishes such energy transfer using lightweigh..

Time-of-Flight Mass Spectrometer Array (TOF Spectrarray)

Method and System for Detecting Small Structures in Images

The potential difficulties and pitfalls of many automated detection techniques can be summarized as follows: a. Too little enhancement may preclude the detection of minor microcalcification peaks whil..

Auscultation Diagnostic Support Device

Current medical training techniques rely on significant patient contact, resulting in high training costs and often not the expected outcomes. In a 1997 study published in The Journal of American Medi..

Core Body Temperature Pill Technology

A multichannel circuit for telemetry signals representing physiological values from a point in a human body to a receiver (24) outside of the body. The two signals (S1, S2) other than the temperature ..

Non-invasive Fetal Heart Signature Monitor

Regardless of the monitoring technique, critical difficulties frequently arise when there is an emergent need to transfer the monitored patient from the labor area to the operating room. The monitors ..

Portable pH Data Collector

The present invention provides an apparatus for continuously recording physiological data. The invention includes a unique data mapping and compression technique, which allows relatively long-term dat..

NONINVASIVE TRANSCERVICAL TUBAL OCCLUSION (STERILIZATION) IN WOMEN

In 1985, Platia and Krudy reported the first successful transcervical catheterization of one obstructed fallopian tube in a woman with bilateral tubal obstruction. Since then a number of reports have..

SYSTEMS AND METHODS FOR COMBINED ULTRASOUND AND ELECTRICAL IMPEDANCE IMAGING

Ultrasound imaging provides good spatial resolution and can identify the borders of tissues, and possibly tumors, but the technique is unable to discriminate between benign versus malignant tissue. E..

THERMAL TREATMENT SYSTEMS WITH ACOUSTIC MONITORING AND ASSOCIATED METHODS

Thermal treatment systems are used, for example, to ablate liver metastatic tumors, treat benign prostatic hyperplasia, ablate cardiac tissue for the prevention of arrhythmia, heat corneal tissue to c..

THE DARTMOUTH ACOUSTIC PLETHYSMOGRAPH: A NOVEL METHOD FOR MEASURING BREATHING IN VERY SMALL ANIMALS

As genetic modification of brain respiratory control processes becomes more advanced, there is great interest in measuring breathing and the development of respiratory control in neonatal mice and rat..

Improved Aneurysm Clips and Improved Aneurysm Clip Applicators

Cerebral Aneurysm Clips Prior art aneurysm clips are fabricated of metal (usually a cobalt metal alloy of steel or titanium). These metallic clips limit the usefulness of non-invasive imaging, i.e..

Magnetic Proximity Sensor System and Associated Methods of Sensing A Magnetic Field

Magnetic Resonance Imaging (MRI) provides an unparalleled window into the human body and is highly regarded as a safe and effective medical technique. There is however a potential for interaction bet..

SYSTEMS AND METHODS FOR tomographic IMAGE RECONSTRUCTION

Diffuse Optical Tomography (DOT) is a relatively new optical imaging modality that uses visible and near infrared radiation for the detection and diagnosis of surface and near-surface anomalies. Meas..

Novel Method for Early Detection of Hypovolemia

Early detection of hypovolemia is clinically important because severe hypovolemia, blood loss of more than 1 liter, can lead to rapid decline and cardiovascular collapse. By the time the tachycardia o..

METHOD AND DEVICE FOR THE NON-INVASIVE DETECTION OF PRE-NEOPLASIA IN VIVO

Dartmouth has developed a system capable of measuring tissue optical properties in vivo. The fluorescence lifetime spectrometer (FLS) is a clinically compatible, portable, fiber based instrument capa..

METHOD AND DEVICE FOR THE MEASUREMENT OF THE PARTIAL PRESSURE OF OXYGEN (pO2) IN VIVO, INCLUDING FOR ROUTINE USE IN CLINICAL SETTINGS INVASIVELY AND NON-INVASIVELY

We have developed a new system which, for the first time, makes it feasible to measure pO2 in the clinical setting with the accuracy, sensitivity, and repeatability needed for effective clinical use. ..

CRUTCH FOOT RESTER(FOOT RESTER ON CRUTCH)

I am an inventor with a new product that I invented “TITLED” CRUTCH FOOT RESTER(FOOT RESTER ON CRUTCH). I invented this product, which goes on the tip of a crutch, so that it will offer people wh..

Implantable Biotelemetry System for Preterm Labor and Fetal Monitoring (ARC-14280)

Abstract: In 1993, The FTC established a relationship with Sensors2000! (S2K!) to adapt NASA's implantable biotelemetry devices to their monitoring needs of the human fetus and its uterine environmen..

Insulin Receptor Knockout Mice

Description: The Insulin/IGF family of ligands and receptors controls mammalian growth, metabolism and reproduction, and insulin signaling at the insulin receptor is implicated in important sign..

Methods and Compositions for Inducing Brown Adipogenesis

Description: The most common fat cells are white adipose tissue (WAT) cells, which have a thin ring of cytoplasm surrounding a lipid or fat droplet. WAT is found underneath the skin and provides..

Exemer Ablation Within Bowman

Abstract (Set) Method and apparatus for laser ablation of the cornea to correct strabismus. The laser beam is controlled by a system of limiting shutters to cut prism lenses into the cornea. The abla..

Corrections for Image Artifacts in MRI

A method for removing image artifacts in MRI created when data acquisition is synchronized to a physiological and therefore uneven intervals. The method simultaneously records both image data from the..

New Inhibitor of Rotavirus

An anti-diarrheic product comprises a foodstuff and an anti-rotaviral agent such as human defatted fat globule membranes, the human milk macromolecular fraction, the milk mucin complex, the 46 Kd appa..

New Surgical Instruments for Vocal Cord Repair

A device and method to lateralize, or alternatively medialize, the vocal cord is described that is adjustable so that the final position of the vocal cord can be adjusted to enhance the quality of the..

Use of Botulinum Toxin for Treatment of Smooth Muscle Disorder

Direct injection of sphincteric botulinum toxin is disclosed as an effective, safe and simple method of treatment for disorders of gastrointestinal muscle or smooth muscles elsewhere in the body, with..

Endoscopic Cryospray Device

A cryoprobe instrument for endoscopic use has been provided that permits the delivery of liquid or gaseous cryogens in the form of a spray. In an embodiment, the cryoprobe instrument includes an elong..

Dosing Model

A drug dosage modeling system that simulates the effect of therapeutic agents in humans to allow accurate evaluation not possible using conventional methods. Description (Set) Proposed Use (Set) ..

Bipolar Cautery Catheter

A bipolar electrocautery valvulotome in the form of an elongated catheter having a longitudinal axis, a proximal end for being held and manipulated by a user, and a distal end. The device is used to r..

A Mouse Model of Hemophilia A

A transgenic mouse deficient in blood factor VIII has been developed. This mouse serves as a model of human hemophilia.

Adaptive and Reconfigurable Chip for DC Motor Control

Abstract (Set) An integrated chip for control of position/velocity and torque of DC motor is provided. The technique uses armature current feedback and on-chip position/velocity estimate from an incr..

Surface-Immobilized Antimicrobial Peptoids (28138)

Northwestern researchers have developed peptoid mimics of antimicrobial peptides that can be immobilized onto surfaces, rendering these surfaces capable of compromising the membranes of attached bacte..

Device and Method for Measuring Spinal Reposition Sense (20013)

Proprioception is used by the body to communicate position sense and appreciation of movement of body parts. Receptors located in muscles, ligaments, tendons, capsules, menisci and the skin provide pr..

Sandwich Holder

INVENTION: The Sandwich Holder enables patients with limited use of their hands to independently feed themselves. In contrast to currently available sandwich holders, the Sandwich Holder delivers the ..

List-mode Image Reconstruction Software for Positron Emission Tomography (PET) Imaging

Abstract (Set) The technology is software capable of performing accurate and efficient reconstruction of a high resolution PET scanner, namely the high resolution research tomography (HRRT). The soft..

Novel Calcitriol Analogs

Abstract (Set) Five to eight million people in the US and 125 million people worldwide have psoriasis. Current treatment of Psoriasis includes Maxacalcitol, an oxa analog of calcitriol which is a nec..

Automate White Matter Parcellation Based on Diffusion Tensor Imaging

Brain white matter looks homogeneous in conventional MR. This makes it difficult to identify specific white matter regions (similar to locate a place in desert). DTI provides contrasts based on axonal..

Biodegradable Polyphosphates for Controlled Release of Bioactive Substances

The present invention includes a series of polycationic biodegradable polymers, the process for making the polymers, and the process for making compositions contain polymers and bioactive ligands. The..

Biofunctional Fibers

The present invention describes a method to functionalize polymeric fibrous scaffolds. Surface biofunctionalization is achieved by linking bio-functional ligands and growth factors onto polymeric bioc..

PECAM-1 Related Compositions and Associated Methods of Use

PECAM-l (CD 31), a member of the IG superfamily, is expressed strongly at endothelial cell junctions, leukocytes and platelets. PECAM-l has been suggested to play a role in angiogenesis, vasculogenesi..

Improved Fitting Calculation For Diffusion Tensor Imaging

Diffusion tensor imging is a new MRI modality, which is becomig a very important technque to assess various tyes of brain diseases. However, this technque has one weakness; its extreme sensitivity to ..

Transplantable Membrane Systems For Use In Ocular Tissue Repair

The present invention is a novel non-immunogenic collagen vitrigel membrane for use in ocular tissue repair. The unique properties of the collagen vitrigel permit it to be transplanted alone or as a s..

Mutant DISC1 Inducible Transgenic Mouse Model of Schizophrenia

Description (Set) Transgenic mice with inducible expression of mutant human DISC1 (hDISC1) limited to forebrain regions were generated. Proposed Use (Set) The mouse model could be used to study of ..

EmboGel / EmboClear Therapeutic Solution � Dissolvable radio-opaque alginate-based biomaterial for endovascular delivery and controlled therapeutic agent release

Johns Hopkins University is seeking licensees for EmboCaps and Emboclear. EmboCaps are an alginate matrix with controllable porosity that provides diffusion-controlled release of therapeutic agents. E..

Pull-Out Resistant Pedicle Screw for Osteoporotic Patients

This novel device is a pullout resistant pedicle screw that will provide enhanced stability and fixation in osteoporotic spine surgery patients. The use of the new pedicle screw may also be indicated ..

A System and Method for Image Based MR Interventional Device Tracking and Scan Plane Guidance

The present invention is a method of using projection images for interventional device tracking. Specifically, the new tracking method involves acquisition, device detection on 2D projection images, r..

Platform for High-Quality 3D Elasticity Ultrasound

The Johns Hopkins University seeks a partner to commercialize a new platform for generating high-quality elasticity ultrasound images. The system uses a novel set of algorithms that integrate with tra..

Optimized MRI Strip Detectors

Strip MRI detectors offer the advantages over conventional detectors of minimal coupling and high-frequency operation as phased arrays. This invention is a method to optimize the SNR for MRI strip det..

A Novel Method for Programmed Release of Biomolecules

Johns Hopkins University seeks a partner to commercialize a novel method for programmed release of biomolecules and nanoparticles. This is a useful tool for the controlled delivery of drugs, DNA, prot..

Multi-Imager Compatible Robot for Image-Guided Interventions and Fully Automated Brachytherapy Seed Injector

The present technology is a robot designed for image based percutaneous needle intervention of the prostate gland. The robot is constructed of nonmagnetic and dielectric materials for complete MR comp..

A Method for the Efficient Functional Examination of Mammalian Noncoding Sequences in Transgenic Zebrafish

sequence conservation is recognized as a reliable indicator of both coding and non-coding functional sequences. Consistent with this hypothesis, coding sequences may be readily identified based on evo..

Microfluidic Device for High-throughput Cellular Gradient and Dose Response Studies

This invention is a microfluidic device made of a silicone elastomer (PDMS) that can be used for dose response, gradient detection, and chemostatic growth studies of most cell types, particularly non..

Device for High-throughput Stimulation, Immunostaining, and Visualization of Single Cells

This invention exploits the high efficiency and exquisite control afforded by microfluidic devices by allowing a group of cells to be stimulated in a precise and dynamically regulated fashion and sta..

Pneumatic Stepper Motor

The present technology is a new pneumatic motor, a pneumatic stepper motor that can be easily controlled for precise motion. Directional rotary motion of discrete displacement is achieved by sequentia..

Image Guided Device for Rodent Brains

Stereotaxic device for rodent brains is widely used for various types of brain surgeries, injections, and other types of manipulations. The device is essential for many research labs in Universities ..

Dual Vector Information via Audible Pulse Oximeter Signals

This invention allows anesthesia providers to audibly detect both a patient�s oxygen saturation and blood pressure. Currently, the pulse oximeter signal carries information about oxygen saturation (..

Modified Pipette Tips for Plasma Collection

Description (Set) Blood collection is a common technique used in a variety of capacities ranging from human to mouse. In all cases, blood coagulation during and after collection can be fairly problem..

A New Method for Co-registering PET and CT Images Acquired in Separate Dedicated Small Animal Scanners

Abstract (Set) Background - Positron Emission Tomography in dedicated small animal scanners is a very attractive imaging modality for many research applications due to the high sensitivity and potent..

Transcaval Mesenteric Venous Anastomosis and Access System

This device is used to create a percutaneous anastomosis between the Inferior Vena Cava (IVC) and the mesenteric/portal system. The subsequent anastomosis can be used to divert blood flow for the redu..

IB3-1

Cystic Fibrosis bronchial epithelial cell line isolated from a patient with genotype ?F508 /W1282X. Cells were immortalized with adeno12SV0. Description (Set) Proposed Use (Set) This cell line ..

A Method of Assessing Vascular Reactivity Using Magnetic Resonance Imaging

precision, using magnetic resonance imaging. The most commonly used noninvasive technique for assessing arterial endothelial function employs ultrasound. There are several improvements using this inve..

A "Wireless" Scleral Search Coil for the Measurement of Eye Movements

The present invention improves upon the existing scleral search coil system by introducing a new ?wireless? contact lens. The new system uses a similar scleral contact lens on the eye but without the ..

Medical Device for Treatment of Ulnar Neuropathy

UlnarGuardTM is a non-invasive medical device used for treating pain and disability due to ulnar neuropathy. It is designed to worn under clothing so that patients can undergo treatment day and night...

Point-of-care Mass Spectrometer

The invention is an apparatus for clinical diagnostics using a point-of-care approach to mass spectrometry technology to provide a single broad-based assessment of viral infection, HIV, and/or cancer...

Disposable Sleep and Breathing Monitor

The apparatus consists of two parts, 1.) a calibrated flowmeter for measuring breathing and 2.) electrical sensors attached to the mask for measuring biomedical signals such as, but not limted to, oxy..

Hypothermia Induction Device

JHU researchers have developed a device that cools the heart and brain from normal temperature to mild hypothermia (35-32?C) within a few minutes. The device cools blood extracorporealy. It requires o..

Modified 0.8 mm-tipped Laparoscopic Dissecting Clamps used to Aid in Cavernous Nerve Preservation During Nerve-Sparing Laparoscopic Radical Prostatectomy

Laparoscopic radical prostatectomy has recently been proposed as a less invasive technique as compared to conventional open radical prostatectomy for the surgical management of prostate cancer. Preser..

The Cysteine Noose of the Attachment Protein of Respiratory Syncytial Virus Inhibits the Effects of the Endotoxin and the Innate Immune Response

Both endotoxin and RSV protein F stimulate CD14/TLR4 receptor in monocyte/macrophages resulting in a strong inflammatory response. In the case of endotoxin, this response has a direct pathogenic role ..

Interventional Devices for Chronic Total Occlusion Recanalization Under MRI Guidance

Recanalization of chronic total occlusion (CTO) is a chanllenging clinical procedure traditionally conducted under x-ray guidance to improve blood flow to patients with symptomatic ischemia. X-ray gui..

A System for Macro-micro Distal Dexterity Enhancement in Microsurgery of the eye

The system is a system for providing dexterity inside the eye for micro-surgical procedures. The system includes a remote center of motion unit (RCM) and a Macro-Micro Distal Dexterity (MMDD) unit. th..

A Highly Accurate Ultrasound-Guided Interstitial Intervention

The Johns Hopkins University seeks a partner to commercialize a new approach to dramatically increase the accuracy of image-guided intervention systems, with the use of interstitial ultrasound. Cl..

A New Ultrasound Imaging Method for Prostate Visualization

The Johns Hopkins University seeks a partner to commercialize a new method of ultrasound strain imaging for prostate therapies. Click here to view high-quality marketing materials. Description (S..

A Novel, Robust Method for Ultrasound Probe Calibration

Abstract (Set) The Johns Hopkins University seeks a partner to commercialize a novel, robust method for calibration of an ultrasound probe. The technique relies on a unique closed-form solution that ..

A Synthetic Torso for Training and Evaluation of Laparoscopic Skills

We report the development a new synthetic torso for urologic laparoscopy training allowing the placement of animal organs in situs. The trainer, Lapman, has the exact shape of a human torso, presentin..

Method of Three-dimensional Video-oculography

JHU researchers describe a novel, inexpensive, method and apparatus for real time measurement of binocular three-dimensional rotational eye position and velocity. The method employs consumer grade dig..

A Novel Robotic Five-Dimensional Ultrasound System

The Johns Hopkins University seeks a partner to commercialize a novel robotic five-dimensional ultrasound system that incorporates four-dimensional ultrasound imaging (three spatial dimensions and tim..

A Radiometric Approach to Temperature Monitoring in the MR Scanner

The present invention offers a novel method of using the Magnetic Resonance (MR) scanner as a radiometer for measuring body temperature. This methodology utilized the radiated thermal noise to estimat..

Using Wireless Electromyographic Data to Infer Hand Applied Forces

In an effort to quantify hand-applied forces without instrumentation of the object, we have developed a force measuring system that can wirelessly transmit force-related information to a data acquisit..

Genetically Engineered "Down Syndrome" Mice

We used chromosome engineering to create mice that have the extra genes in a ?critical region? proposed to cause Down syndrome. These mice can be assessed for mental retardation as well as problems th..

MRI Flex Circuit Catheter Imaging Coil

The invention is a long, narrow, thin flexible piece of printed wiring board that can fit into an 8 French cardiac catheter that acts as a shielded coil useful for picking up magnetic lines of flux in..

MRI Compatible Positioning Arm

Scientists at Johns Hopkins have developed a family of passive positioning arms designed to carry a robot, instrument, or other tool at its distal end. The prototype has full six degrees of freedom (3..

Process of Fiber Fabrication by Intrefacial Polyelectrolyte Complexation and the Encapsulation of Biological Materials Within Said Fibers

This invention includes a method of producing drug-loaded fibers using interfacial polyelectrolyte complexation for tissue engineering. Fibers are produced by pulling from the interface between two p..

Electroporation System for Enhancing Wound Healing Using Plasmid DNA Expression Vectors

We have invented a gene therapy protocol (system, kit) that enhances wound healing. Our approach is to combine the application of plasmids expressing growth factors and the technique of electroporatio..

A Chitosan-DNA Mucosal Vaccine For Respiratory Syncytial Virus Infection

A gene expression vaccine (GXV) comprising of a cocktail of pDNAs encoding nine immunogenic antigens was developed in the form of chitosan-DNA nanospheres. This GXV was tested in a BALB/c model of RSV..

Miniaturized Sample Scanning Mass Analyzer

This mass spectrometer is being developed as a compact analytical instrument capable of handling large sample arrays, such as the 96 and 384 microtiter sample formats. It is aimed at both research and..

Device, Method, and System For Needle Insertion Inside a Medical Imager, From Within Body Cavity

The Invention is a device, computerized system, and methods for entering a needle into the body inside a medical imager such as a MRI scanner, CT, X-ray fluoroscopy, and ultrasound imaging, from withi..

Adjustable Remote Center of Motion Robotic Module

The invention is a robotic module that can be used to orient an end-effector about two axes intersecting at a fixed geometric point located distal to the mechanism materializing a pivot point or a Rem..

Noninvasive System for Assessing Cardiac Filling Pressure

Abstract (Set) The invention is a system for assessing cardiac filling pressure noninvasively. It consists of a device and method that can be used at the bedside, in clinic, in the emergency departme..

Combination device and solution for efficient removal of insect from the ear canal

Abstract (Set) Johns Hopkins University is seeking a licensee for a combination solution and device for efficient removal of insects from the ear canal. A JHU Emergency department study showed that i..

Ambulatory Raynaud's Monitor

Monitoring a person?s response to cold by recording their skin temperature is a key physiological response parameter for identifying Raynaud?s. This device would provide the means for physicians to de..

System For Refibrillation of the Heart For Treatment of Post Countershock Pulseless Electrical Activity and Asystole

A method and/or system for inducing ventricular fibrillation (VF) of the heart for treatment of post-countershock pulseless electrical activity (PEA) or asystole. In certain example embodiments, it ha..

A Multiple-projection DXA Scanner for Improved Accuracy and Precision in the Measurement of Bone Cross-sectional Geometry and Body Composition

Osteoporosis and a number of other diseases and conditions alter the mechanical strength of the skeleton such that bones fracture easily. A number of treatments exist that can mitigate the loss of bon..

Laser-based CT and MR Registration

A simple method for robot and precise instrument registration in computer tomography and magnetic resonance imaging systems. The method uses the laser markers readily available on any CT or MR scanner..

Design and Fabrication of High Performance AFM Cantilivers

High performance cantilevers with optimal combinations of high resonant frequency and low force constant are provided. AFM cantilevers with spring constants in the range 1-10-6 N/m with fundamental re..

Accessing the Scala Media of the Inner Ear with Robot Assistance

Accessing the scala media of the cochlea would permit the delivery of drugs, growth factors, gene therapy vectors and cells in order to treat hearing loss of cochlear origin. Many forms of hearing los..

Clinician's Portable, Digital, Intelligent Assistant (Pain Informatics Program)

The input devices are mobile pen-based computers and palm pad systems that will emulate and expand the clinician's present paper patient system. The system will provide for semi-automation of the coll..

The Cardiac Ausculatory Recording Database (CARD): an Internet-based software Program and Digital Heart Sound Recording Database for Teaching and Study of Cardiac Auscultation

The Cardiac Auscultatory Recording Database (CARD) was also developed. Developed using the Microsoft Access relational database program, CARD is available online through the World Wide Web. CARD conta..

Analysis of Cardiac MR Relaxation Time Images with Application to Quantifying Myocardial Perfusion Indexes

The present invention is a method and apparatus for semi-automatically registering low signal to noise ratio relaxation-time images, with particular application to tracking motion in moving organs and..

Controllable Motorized Device for Accurate Percutaneous Needle Placement in Soft Tissue Target

The invention is a motorized controllable needle driver for percutaneous delivery of needles and devices of circular cross section profile to soft tissue targets inside the body. The device can be use..

Auscultation Diagnostic Support Device

This invention is a screening tool for heart and lung aliments. Advanced signal processing techniques have been applied to heart and lungs sounds as an aid to diagnoses. A database containing patient ..

Near-field Radio Frequency Planar Strip Array Antenna for NMR Imaging

A device for detecting electromagnetic signals, more specifically, the magnetic resonance signals from excited nuclei as well as related apparatuses, systems and methods is provided. This detection de..

Transgenic Mice Expressing a Truncated Mutant of Rat Cardiac Troponin

Stunned myocardium is a reversible contractile failure secondary to coronary artery disease. It has been found that selected proteolysis of the protein troponin is associated with stunned myocardium a..

Circumferential Pulmonary Vein Ablation using a Laser and Fiberoptic Balloon Catheter

The purpose of this invention is to deliver near-infrared laser radiation radially from a diffusing optical fiber through an optically transparent distendable balloon to create complete circumferentia..

Gastric Reduction Endoscopy

Methods and devices for partitioning or plicating a region of a hollow body organ are described herein. These methods and devices relate generally to medical apparatus and methods and more particularl..

Transgastric Peritoneoscopy

A novel approach to diagnostic and therapeutic interventions in the peritoneal cavity is described. More specifically, a technique for accessing the peritoneal cavity via the wall of the digestive tra..

A Flexible Retinal Vessel Cannulation Device

A microcatheter system that allows for vascular infusion into retinal veins for extended periods of time. The microcatheter system includes a flexible cannula that is inserted into the retinal vein lu..

Method for Parallel Spatial Encoded Magnetic resonance Imaging

In a MR imaging system spins in a selected slice of the object are excited by RF excitation pulse and the signal is then received by an array of RF detectors. The phases of signals from multiple chann..

Intraoperative Microsurgical Ultrasound Device

Featured is a device that provides a mechanism for imaging structure and/or tissue of a surgical site during and after performing a microsurgical procedure such as ophthalmic surgical procedures. Als..

Surgical Device for Enhanced Perception

Featured are surgical devices that provide enhanced perceptual feedback to a medical practitioner in the form of e.g. tactile sensations or auditory feedback, and methods of use of the devices. The de..

Cardiac Sock Electrode and Implantable Defibrillator System

An object of this invention is to provide an implantable cardioverter defibrillator (ICD) system and/or method that is less painful to a patient than one or more conventional ICD systems/methods. Anot..

Non-traumatic Infusion Cannula

In preferred aspects, the present invention features a non-traumatic cannula for use in connection with eye surgery, such as retinal tear and/or detachment surgery. The non-traumatic cannula of the pr..

Injectable Bag Intraocular Lens System

Featured is an injectable intraocular lens system including an insertion and injection device and an injectable intraocular lens. In its broadest aspects, the injectable intraocular lens is a deflated..

MR Safe Coaxial Cables

This invention is a novel coaxial cable design that will reduce the induced currents and hence the risk of excessive heating or burns in MR scanner. Compact resonance circuits/structures are placed al..

A Surgical Needle Probe for Electrical Impedance Measurements

An electrical impedance probe constructed within a surgical needle. The probe consists of a two-part trocar needle designed to acquire impedance measurements at its point. Since the impedance of cells..

Brain Stimulation as a Treatment for Seizures

The present invention includes adaptive technologies to detect and treat brain seizures. Neural networks or other mathematical methods which model seizure patterns are used to detect the seizures. A n..

Tympanic Membrane Prosthesis with Mechanical Fixation

Perforations of the tympanic membrane result from many different processes such as infections of the middle ear, direct trauma to the eardrum, or poor post-operative healing. They usually do not prese..

Passive Intraocular Pressure Sensors & Patient-Worn Monitorying Recorder

A device for passively measuring intraocular pressure of a patient including an in vivo sensor and an instrument external to the patient for remotely energizing the sensor, thereby permitting the inst..

Eye Fixation Monitor and Tracker

The eye fixation monitor can non-invasively and remotely detect when a human eye looks directly at it. The apparatus illuminates the eye with infrared light energy, uses a photodetection system to ana..

Friction Transmission with Axial Loading

As a common characteristic of friction rotational-translational transmissions, the force generating the friction was oriented radial with respect to the rotational shaft of the transmission. Our appro..

Method to Objectively Quantify the Level and Density of a Neural Blockade

Electromyogram (EMG), temperature, and heart rate measurements, which correlate to the dermatomal level and density of neural blockade, are obtained in a passive manner, i.e., the patient is not stimu..

Device forTranstracheal Insufflation in Treating Obstructive Sleep Apnea

A novel ventilatory support system which controls the flow of breathing gas to a patient based upon the physiological need of the patient is disclosed. Gas pressure in the trachea of the patient is mo..

Method for Assessing Cardiac Contractility and Cardiovascular Interaction that may be Applied to Non-Invasive Clinical Practice

It has been found that E.sub.N (t.sub.N) curves are surprisingly similar among hearts, particularly during early contraction. Based on this observation, the present invention provides an arrangement (..

A Method for Designing Non-Linear Field Reflectrons

This is an approach to the design of reflectron time-of-flight mass analyzers that utilizes a cylindrical geometry to achieve nearly-quadratic retarding and reflecting fields without employing a set o..

Transcatheter, Non-surgical Left Ventricular Assist Device

The invention comprises a method and device for draining blood from the left atrium of the heart by utilizing a cannula and catheter in which a guide wire and a needle assembly are positioned axially...

Cryo Filter Exchanger

This device maintains parallelism between diffracting crystals while allowing the crystals to continuously travel through high to low take-off angles. A central shaft that rotates by one half of the v..

Virtual Instrument & Permeability System

This camera-based system provides improved water permeability measurement over prior LED methods. Rather than tracking air bubbles by sensing light transmisson, this system uses a camera and virtual i..

Copper-Based Probes for Determining Nucleic Acid Structure In Vitro and In Vivo

The present invention is related to a novel method for splitting nucleic acids at specific points on a complementary nucleic acid segment using a trinuclear copper-based compound of formula (I). Addit..

Multi-Band Image Analysis

Computation of contrast, which includes computation of gradient and zero-crossings, has been used in computer vision as one of the primary methods for extracting grayscale and color features. It seems..

Miniature Immuno-Optical Rapid Analyte Sensor Platform

A hand held, self-contained, automatic, low power and rapid sensor platform for detecting and quantifying a plurality of analytes. A sample solution potentially containing an unknown amount of an anal..

Apparatus and Method for Exercising and Measuring Strength of a Patient's Limb

An apparatus for measuring the strength of and for performing physical therapy exercises to strengthen a patient's limb. The device includes a pair of pivot clamps each having a end for connecting the..

Polarization Lens

The present invention pertains to a polarization viewer. The polarization viewer comprises a mechanism or means for forming a broadview image having a spectral width preferably greater than 2 angstrom..

Skills Trainer for Robotic Surgery

Robotic surgery is becoming increasingly popular with the advent of robotic technology in medicine. With this, there arises a need to extensively train the surgeons to effectively use these devices. S..

CPAP titration using artificial neural network

For 18 million Americans suffering from Obstructive Sleep Apnea (OSA) this is as frustrating as a dog chasing its tail. Lack of proper sleep can lead to severe health problems and increased risk of ac..

Intestinal Coupling Device

Esophageal atresia with tracheal esophageal fitula occurs in approximately 1 in 1500-5000 newborns. This is a congenital defect in which the esophagus does not form a continuous connection to the stom..

Esophageal Coupling Rings

Esophageal Coupling Device

Catheter for endovascular intervention

A University at Buffalo radiologist has developed novel stent vascular devices for the treatment of cerebral aneurysms. The nature of these neurovascular stents and other devices like them make deploy..

Non-Invasive Screening Device for Upper Aerodigestive Tract Neoplasia

Diagnostic medical equipments are probably one of the most important paraphernalias of the medical field. This is because of the fact that in all the medical procedures, diagnosis is the first step to..

Methodology for the Synthesis of fluoride (NaYF4) nanophosphors co-doped with Gd3+ and other rare-earth ions and its applications in security printing and bimodal (optical and MRI) imaging

Methodology for the Synthesis of fluoride (NaYF4) nanophosphors co-doped with Gd3+ and other rare-earth ions and its applications in security printing and bimodal (optical and MRI) imaging Categor..

Skills Trainer for Robotic Surgery

Catheter for endovascular intervention

CPAP titration using artificial neural network

Non-Invasive Screening Device for Upper Aerodigestive Tract Neoplasia

Intestinal Coupling Device

Esophageal Coupling Rings

Esophageal Coupling Device

Stent Vascular Intervention Device and Method Modification

A team of University at Buffalo researchers has developed novel stent vascular devices for the treatment of cerebral aneurysms. The new stents can be deployed by a conventional balloon-catheter and a ..

Stent Vascular Intervention Device and Method Modification

Solid Cone Liquid Cooled Design

Introduction Therapeutic ultrasound refers to the use of high intensity ultrasonic waves to induce changes in living tissue state through both thermal effects and mechanical effects. Ultrasonic applic..

Cell and Microparticle Separator Employing Patterned Grooves

Introduction Microscale enrichment and separation are important for various research, biomedical, and industrial uses. Conventional means for these processes typically require specific labels— eith..

Nanobioelectronics: Building functional hybrid nanoelectronic/cell circuit elements

Summary Background: The determination of electrophysiological properties is important for understanding signal propagation through individual neurons and neuronal networks as well as muscle tissue. H..

"MoleProbe": A Real-Time Molecular Diagnostic Device

Summary A novel engineering method for generation of freestanding 2-D and 3-D tissue structures. Biopolymers (proteins, carbohydrates, lipids, nucleic acids or combinations thereof) are deposited onto..

Torque-Actuated Valves for Microfluidics

Summary Background: A number of active and passive valves for microfludic systems, based on bubbles, pneumatics, electrokinetic, and other mechanical solutions, have been developed. So far these so..

Enhanced Nanoparticle-Based Molecular Imaging via MRI

Summary Enhanced Nanoparticle-Based Molecular Imaging via MRI Elevator pitch: For biotech and pharmaceutical companies who need to track drug effectiveness in the drug discovery and for MRI facili..

Compounds and Methods for Tumor-Specific Targeting

Summary A novel strategy for developing cancer-homing drugs has been developed by Dr. Amin Kassis that combines Enzyme-Mediated Cancer Imaging and Therapy (EMCIT) with radionuclides (see figure below)..

Biological Computers: In Vivo Autonomous Doctors that Diagnose and Treat Disease

Summary Background: The promise of computers made from biological molecules lies in their potential to operate within the biochemical environment of a living organism and to interact with that environ..

Slowing Down Light for Enhanced Detection of Biomolecules

Summary Allows for optical sensing and chemical and biological detection using extremely small and highly-sensitive devices. Also allows for fabrication of exceptionally small lasers for applications ..

Robust and inexpensive actuator to generate motion in small-scale devices

Summary Innovation and Advantages: The invention is a novel design and fabrication of a millimeter scale SMA actuator used to generate motion. In addition, the researchers have developed a novel syste..

New Nitrate Measurement Method

Summary By employing novel filtration methods, this semi-continuous ambient particulate nitrate monitor measures the concentration of particulate ammonium nitrate (NH4NO3) contained in PM2.5. The ..

Torque-Actuated Valves for Microfluidics

Summary Background: A number of active and passive valves for microfludic systems, based on bubbles, pneumatics, electrokinetic, and other mechanical solutions, have been developed. So far these so..

Nanobioelectronics: Building functional hybrid nanoelectronic/cell circuit elements

An Ultra Low Power System Architecture for Sensor Network Applications

Summary Ultra-low-power chip for sensor network applications Application and Benefits: Wireless sensor networks (WSNs) are used in a wide variety of applications including environmental monitoring..

Controlled Synthesis of Millimeter-Long Silicon Nanowires with Uniform Electronic Properties

Summary Background Single-walled carbon nanotubes (SWCNTs) and semiconducting nanowires (NWs) are attractive building blocks for fabricating numerous functional nanodevices such as FETs, light emit..

Smart Balloon Catheters for Diagnosis and Therapy of Narrowing Lumen

Summary Modern techniques for the diagnosis and treatment of narrowing of lumen can use dilating balloon catheters. A common risk with such procedures -- for instance, in the case of peptic and non-pe..

A Novel Color Filter Array Design

Summary Background In digital imaging applications, data are typically obtained via a spatial subsampling procedure implemented as a color filter array (CFA). CFA assigns a separate primary color t..

Device and Method for Restoration of Sight through Patterned Thalamic Microstimulation.

Summary This technology aims to restore sight in people who are blind due to disease or injury by placing an electrode implant in a part of the vision system known as the lateral geniculate nucleus (L..

Target-locking Confocal Microscope System

Summary Eliminating tumors via a non-invasive target-locking technology Markets/Needs Addressed: Many tumors occur in parts of the body that are difficult to locate and image dynamically (e.g., c..

Biological Computers: In Vivo Autonomous Doctors that Diagnose and Treat Disease

Novel way of brain mapping to be used in pre-surgical planning

Summary Innovation and Advantages: Harvard researchers have developed a method for mapping the organization of a patientâ€™s brain for pre-surgical planning by using functional MRI, but without r..

Slowing Down Light for Enhanced Detection of Biomolecules

Robust and inexpensive actuator to generate motion in small-scale devices

New Delivery Device for Protein Therapeutics and Vaccines

Summary Harvard's researchers have developed a new device for protein and gene delivery. It makes use of the unique ability of unicellular organism protozoa to infect a host, evade their immune defens..

Animal Model of Diabetes and Obesity: Cross-bred JNK1 KO/JNK 2 KO Mice

Summary Mice with the JNK 1 and JNK2 genes knocked out were crossed with the obese mouse line (ob/ob) to create a mouse model of diabetes and obesity. These mice exhibit many of the hallmark metabolic..

Elucidating Novel Protein Interactions Using MALDI-MS and a Self-Assembled Monolayer Chip

Summary The ability for real-time identification of protein binding from whole cell lysates is a challenge for protein microarrays. This invention uses MALDI-MS to analyze complex biological mixtures ..

Enhanced Nanoparticle-Based Molecular Imaging via MRI

Summary Enhanced Nanoparticle-Based Molecular Imaging via MRI Elevator pitch: For biotech and pharmaceutical companies who need to track drug effectiveness in the drug discovery and for MRI facili..

Nanobioelectronics: Building functional hybrid nanoelectronic/cell circuit elements

Crosslinkable Hole Transporting Materials for Organic Lightemitting Diodes

Introduction High-performance organic or polymer light-emitting diodes comprise multilayer configurations having hole-transporting, emissive and electron-transporting layers to balance the injection a..

Non-toxic protocol to establish paraoxonase 1 (PON1) status

Introduction Paraoxonase 1 (PON1) is a member of a three-gene family localized on human chromosome 7. Due to its role in the metabolism of both lipids and organophosphorus (OP) compounds, genetic var..

Use of Adhesion Molecules as Shear-Induced Nanoscale Binding Switches

Introduction Methods, compositions, and devices for using shear-dependent binding switches in a variety of applications would be extremely useful in biomedical and other fields. Applications for this ..

Optical Coherence Tomography: High-Resolution Balloon Catheter Imaging, Dispersion Management, and Lateral-Priority Real-TimeImaging and Focus Tracking

Introduction Optical coherence tomography (OCT) is an imaging technique that uses light to acquire three-dimensional images of biological tissue. This non-invasive technique generates highquality imag..

Optimal Fitting of Prosthetic Limbs: Evaluation of Prosthetic Socket Quality and Soft-Tissue Response

Introduction The process of fitting prosthetic limbs to amputees can be a long process of trial and error. Two common obstacles to the optimal fitting of prosthetic limbs are improperly tooled prosthe..

A Microfluidic Device and Methodology for Rapid, Quantitative Determination of Analyte Concentration in a Fluid Sample

Introduction Advances in microfluidic technology are constantly opening doors to new and exciting applications, especially for biosensors and environmental monitoring. One recent area of interest is p..

Localization Wire for Surgical Excision of Breast Lesions

Introduction With the introduction of screening mammography, the median tumor size has decreased considerably, and approximately half of breast cancers in surgical practice are non palpable and amenab..

Novel Gadolinium nanoparticles for Magnetic Resonance Lymphatic Imaging

Introduction Gadolinium (Gd3+) is chelated with diethylenentriaminepentaacetyl (DTPA) to provide contrast in magnetic resonance (MR) imaging to identify pathogenic tissues. Unfortunately, the Gd3+-DTP..

Platelet Clotting Force Array

Introduction Advances in microfluidic technology are constantly opening doors to new and exciting applications, such as point-of-care diagnostic devices. These microscale diagnostic platforms will ena..

Dynamic Characterization of Particles Using Flow Cytometry

Introduction Flow cytometry is an increasingly useful analytical technique that utilizes the scattering of laser light to interrogate a variety of microparticles, including microorganisms, cells, and ..

Tissue-Engineered Urinary Bladder Using Autologous Cells

Introduction There is a variety of reasons that a person’s bladder may fail or require removal, including bladder acontractility, cancer, and cystitis. Unfortunately, conventional artificial bladder..

Advanced Biomimetic Surfaces for Surface-Enhanced Raman Spectroscopy (SERS)

Introduction Raman spectroscopy characterizes molecules by their Raman scattering. As incoming light scatters off a molecule, most does so elastically, neither gaining nor losing energy, and this is k..

Technique for Detecting Loose Arthroplasty Components

Introduction Due to traumatic injury, severe arthritis, and similar conditions, total joint replacement surgery (or arthroplasty) is becoming increasingly common. Despite the field’s maturity, howev..

Ultrasonic Probe for Determination of Kidney Stone Size

Introduction Kidney stones are a common problem for men and women worldwide that can cause great pain and lead to complications, such as infection. Conventional treatments such as extracorporeal shock..

Cavitation suppressor for shock wave lithotripsy and shock wave therapeutics

Introduction Shock-wave devices are commonly used clinically for therapeutic treatment. For example, electrohydraulic shock-wave lithotripters generate a focused shock-wave for the fragmentation of ki..

Networked Surgical Robot Control System

Introduction The individual soldier remains the most valuable asset of the military and in spite of the current emphasis on the threat of weapons of mass destruction, and biological warfare, attending..

A Staged Balloon-Tipped Overtube for Endoscopic Peritoneal Access

Technology description Researchers at the UW have developed a staged balloon-tipped overtube for improved peritoneal access, particularly applicable to trans-gastric endoscopic surgery. The field of m..

Evanescent Wave Coupling Sensor for Shear/Pressure Measurement

Introduction Lower limb complications associated with diabetes include the development of plantar ulcers that can lead to infection and subsequent amputation. Several authors have postulated that shea..

Novel Spherical Mechanism for Minimally

Introduction Minimally invasive surgical instruments coupled with robotics are being used in a vast array of modern surgeries to minimize patient trauma and reduce recovery time. As these instruments ..

A Method and Design for Performing Rapid Parallel Microfluidic Molecular Affinity

Introduction Point-of-care diagnostic testing, or testing performed at the patient bedside, allows physicians to diagnose patients more rapidly than traditional laboratory-based testing. Rapid results..

A Prosthetic Liner incorporating Shear & Pressure Sensors

Introduction Fitting prosthetic limbs for amputees is a time-consuming, tedious process that is more art than science, often requiring ten or more visits by the patient before the proper fit is achiev..

Periarticular Plates

Introduction A bone plate is typically used to maintain different parts of a fractured bone substantially stationary relative to each other during and/or after the healing process in which the bone me..

Signal Amplification Method for SPR-based Chemical Detection

Introduction Surface plasma resonance (SPR) is a general spectroscopic method for sensing refractive index changes near the surface of a metal film. Its sensitivity to these changes provides a versati..

Interactive 3D Registration of Ultrasound and Magnetic Resonance Images based on a Magnetic Position Sensor

Introduction Accurate guidance and localization of the surgical tool within the brain is essential for the success of various neurosurgical procedures, such as biopsy or tumor resection. Stereotactic ..

Improved Transducer Design for Medical Ultrasound

Introduction Ultrasonography is a noninvasive medical imaging technique, which utilizes ultrasonic waves in order to visualize soft tissue within the body. Advances in this technology have led to a th..

Microfabricated multiplexed devices for sample application and sample delivery to a microelectrospray-mass spectrometer

Introduction The most conclusive and reliable protein identification method is based on correlating collision-induced dissociation (CID) mass spectra of peptides with sequence databases. CID spectra o..

Wearable Low Vision Aids Using Retinal Light Scanning Technologies

Introduction Severe visual impairment (those persons classified as legally blind) affects over 1 million Americans currently. With the aging of the U.S. population, this visually impaired segment is e..

Ultrasound Simulator for Craniosynostosis Screening

Introduction An infant’s skull has free floating bone plates connected by fibers called sutures. When the brain grows, the sutures allow the skull to expand to accommodate the growing brain such tha..

Endoscopic Imaging Devices Using Micromotor Scanners

Introduction Endoscopes are increasingly involved in performing common surgical procedures and in diagnosing cancer and other medical conditions. New technologies can demonstrate significant cost savi..

Programmable Logic Controller Safety System for Surgical Robot

Introduction Surgical robotics is revolutionizing the way in which clinicians deliver health care. As the field of surgical robotics continues to evolve, it is important to keep patient safety in mind..

Dependant Patient Lift Assist Sling

Introduction All dependant patients are different in their needs from physical therapists and other care providers. For those patients that require assistance when standing from a seated position, cur..

A Bifunctional Poly(ethylene glycol) Silane Immobilized on Metallic Oxide-Based Nanoparticles for Conjugation with Cell Targeting Agents

Introduction Magnetic resonance imaging (MRI) is a non-invasive diagnostic and therapeutic methodology. The limitations of this imaging system are in its resolution. Lesions within the body must be ap..

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