Methods for Determining Similar Sequences Across Genomes

Deadline: 2019-11-23
Award: $50,000
Open to: Everyone*

Individuals of a species differ from one another at the genetic level to various degrees. To deeply characterize the genetic content for each individual genome, it is important to understand which sequences of common ancestry have been inherited, possibly in a modified form, across the genomes. Existing knowledge about a gene variant from a well-characterized genome can be applied to better understand other variants, or alleles, of the same gene in different, uncharacterized genomes. Knowledge of which sequences represent the same genes in different individuals is necessary to understand the impact of similarities or any differences that may exist in the gene sequences of individuals from different genetic backgrounds.