Allosteric Inhibitors of Pyruvate Kinase (09/799,873 (US)): small molecules that modulate pyruvate kinase to increase oxygen delivery to tissues.
5-Membered Heterocyclic Antisickling Agents to Treat Sickle Cell Disease (03787240.5-2101-US0338264 (US)): small molecules that bind hemoglobin and increase oxygen affinity to inhibit red blood cell sickling.
Anti-sickling agents (7160910 (US)): small molecules that bind hemoglobin and increase oxygen affinity to inhibit red blood cell sickling.
Antiviral Compounds and Methods of Using Thereof (60/884,928 (US), and 08727634.1-1216PCT/US2008050975 (Europe)): small molecules that inhibit filoviruses.
Small Molecules and a Pharmacophore Model for Inhibition of Botulinum Toxin and Methods of Making and Use Thereof (7574,340 (US)): small molecule inhibitors of botulinum neurotoxin metalloprotease activity to treat botulism.
Compounds having Antiestrogenic and Tissue Selective Estrogenic Properties, and Compounds with Antiandrogenic Properties for Treating: anticancer agents.
Small Molecule Inhibitors of Botulinum Neurotoxins (7,825,154 (US)): small molecules that inhibit the metalloprotease activity of botulinum neurotoxins to treat botulism.