Problem Solver

James Burnett

Areas James Burnett is Knowledgeable in:

General, scientific problems.

Small molecule therapeutics and drug development.

Any chemistry related problems.

Cheminformatics.

Biological problems as they relate to chemistry.

Biological problems having to do with entomology.

Techniques James Burnett Uses:

To solve problems I look for the simplest, low cost, non-traditional solutions.

I use a common sense approach founded in having worked construction as a teenager .

I like to use input from others to gain perspective, communicate my ideas to them (no matter how seemingly absurd), and then tailor a solution to a particular individual or organization.

I look closely at what can be realistically done, and design a solution matrix around resources available.

James Burnett's Problem Solving Skills:

  1. Medicinal chemistry, structure-based drug design, grant writing, scientific reasearh in general

James Burnett's Problem Solving Experience:

  1. I use medicinal chemistry and molecular modeling approaches to identify and develop small molecule inhibitors of target enzymes/proteins.

    I am part of a team that identified a an anti-sickle cell drug that is in Phase 1 clinical trials.

    I have synthesized bioactive agents that modify hemoglobin so that it delivers more oxygen to tissues.

    I have written several research grants to identify and develop counter-bioterrorism agents. The funding agencies: DTRA, NIAID/NIH, and Nato.

    I am part of a team that identified some of the first small molecule inhibitors of bacterial toxins, such as Botulinum Neurotoxins.