Novel Assay

The invention relates to a translational recoding reporter construct comprising: a first fluorescent protein coding sequence; a second fluorescent protein coding sequence encoding a fluorescent protein different from the first fluorescent protein; and a linker sequence interposed between the first and second fluorescent protein coding sequence; wherein the a first fluorescent protein coding sequence and the second fluorescent protein coding sequence are out-of-frame with respect to each other but are co-expressed as a single fusion polypetpdie upon recoding. The invention also relates to methods of use of the construct in screening modulators of recoding.

Attached files:


Patents:
US 20,090,215,051

Inventor(s): CARDNO TONY STUART [NZ]; TATE WARREN PERRY [NZ]

Type of Offer: Sale



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