Ngal-binding Siderophores and Use Thereof to Treat Iron Deficiency and Iron Overload
The invention provides compositions comprising a lipocalin, such as NGAL, and a mammalian siderophore that are useful as iron chelators and iron donors. The invention also provides mammalian siderophore compounds of Formula (I): The invention further provides, methods of treatment and methods of diagnosis.
Attached files:Patents:WO 2,010,033,847
Inventor(s):
BARASCH JONATHAN [US]; DENG SHIXIAN [US]; BAO GUANHU [US]; LANDRY DONALD W [US]
Type of Offer:
Licensing
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