Areas Miguel Aon is Knowledgeable in:
* Bioprocess and host cell optimization for production of biologics
* Microbial physiology and metabolism as applied to fermentation biotechnology
* Metabolism in metabolic disorders due to diabetes and obesity
* Role of mitochondria in diabetic cardiomyopathy
* Writing and editing scientific books
Techniques Miguel Aon Uses:
* Employ an integrated experimental and computational modeling approach.
* Apply multiple experimental techniques to the same problem seeking consistency in the answers obtained from each one of them.
Miguel Aon's Problem Solving Skills:
- Experienced in the use of radioactive tracers
- Mathematical modeling
- Mitochondrial physiology
- Two photon microscopy fluorescence imaging
- Monitoring and interpretation of heart function
- Soil biochemistry and microbiology
- Batch and continuous cell culture techniques
- Physiological and metabolic monitoring of cell culture performance
- Analysis and interpretation of time series of physiological variables
- Fluorometric detection of fluorescent probes
Miguel Aon's Problem Solving Experience:
- Developed a procedure to translate metabolite profiles into metabolic fluxes, and applied it to heart function.
- Formulated research techniques and approach to demonstrate the role of mitochondrial energetics in heart failure.
- Implemented advanced imaging techniques to monitor biochemical processes in living cells, tissue and intact organs.
- Designed a reactor coupled to a gas detector to measure soil gases content (oxygen, carbon dioxide).
- Developed methods to measure enzymatic activity in soil samples.