A method is provided for assessing the potential of one or more test compounds to disrupt the endocrine system. The method comprises measuring the effect of the test compound(s) on hormone sulphation, oestrogen synthesis, and thyroid hormone and/or growth hormone function. These tests may be carried out sequentially or in parallel. Also provided is a test kit for assessing the endocrine disruption potential of a compound. The kit comprises means for assessing the effect of a compound on hormone sulphation, oestrogen synthesis, and thyroid hormone and/or growth hormone function. The kit may also contain comprise one or more optional control test compounds.
WARING ROSEMARY HOPE [GB]; RAMSDEN DAVID BOYER [GB]
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