Synthesis of Ageladine a and Analogs Thereof

The invention describes a one pot process for synthesizing a compound of structure (I), or a tautomer thereof. A compound of structure (II), or a tautomer thereof, and an aldehyde of structure RdCHO are condensed to form a condensation product. The resulting condensation product is then oxidized in the same reaction mixture to produce the compound of structure (I) or a tautomer thereof.

Attached files:
WO 2009152584.jpg

Patents:
WO 2,009,152,584

Inventor(s): KARUSO PETER HELMUTH [AU]; SHENGULE SUDHIR RAMNATHRAO [AU]

Type of Offer: Sale



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