Composition and Method for Treatment of Preterm Labor

The invention provides a method for treating or preventing preterm labor in pregnant female subjects. The method comprises the step of administering a therapeutically effective amount of a Toll-like Receptor 9 antagonist sufficient to prevent the activation of Toll-like Receptor 9 by fetal DNA. The invention further provides compositions comprising a Toll-like Receptor 9 antagonist for use in the methods of the invention. Said compositions and methods enhance gestation and therefore improve neonatal morbidity and mortality.

Attached files:


Patents:
WO 2,010,034,779

Inventor(s): O'NEILL LUKE ANTHONY [IE]; O'LEARY JOHN [IE]; DALY SEAN [IE]; SCHARFE NUGENT ANDREA [IE]

Type of Offer: Sale



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