Cyclitols and their Derivatives and their Therapeutic Applications
The present invention is directed to polyphosphorylated and pyrophosphate derivatives of cyclitols. More particularly, the invention relates to polyphosphorylated and pyrophosphate derivatives of inositols. The invention also relates to compositions of the polyphosphorylated and pyrophosphate derivatives of inositol and other similar, more lipophilic derivatives, and their use as allosteric effectors, cell-signaling molecule analogs, and therapeutic agents.
LEHN JEAN-MARIE [FR]; POTHUKANURI SRINIVASU [FR]; KOUMBIS ALEXANDROS [FR]; DUARTE CAROLINA [FR]; NICOLAU CLAUDE [US]
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