Nucleic Acids of Pichia Pastoris and Use Thereof for Recombinant Production of Proteins
The present invention provides the genome sequence of Pichia pastoris and manually curated annotation of protein-coding genes. The invention provides novel nucleic acids, proteins, and related expression vectors useful for genetic engineering of methylo trophic yeast strains, as well as engineered methylotrophic yeast strains particularly Pichia pastoris, and use thereof for recombinant production of heterologous proteins including glycoproteins suitable for use in mammals including humans.
CALLEWAERT NICO L M [BE]; DE SCHUTTER KRISTOF [BE]; TIELS PETRA [BE]; LIN YAO-CHENG [BE]
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