The Use of Topoisomerase Type I Inhibitors to Treat Viral Infections

The present invention relates to the use of compounds, inducing isgylation to treat viral infections. More specifically, the invention relates to topoisomerase type I inhibitors, such as camptothecin and camptothecin derivatives to treat viral infections, preferably infections by RNA viruses. The invention relates further to the measurement of the level of ISG15 and or the level of isgylation during or after treatment as a method to measure the efficacy of the antiviral treatment.

Patents:
WO 2,010,020,676

Inventor(s): TAVERNIER JAN [BE]; PATTYN ELS [BE]

Type of Offer: Sale



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