Sphingosine- 1- Phosphate (s1p) Receptor Compounds

The invention relates to compounds, in particular 2-amino- 3, 4, 5, -trisubstituted thiophenes, pharmaceutical compositions containing them and the uses of said compounds and compositions for diseases related to sphingosine-1-phosphate (S1P) receptors, predominantly SlP3 receptors. The diseases include cardiovascular diseases, atherosclerosis, cancer, pulmonary oedema, autoimmune disorders and Adult Respiratory Distress Syndrome.

Patents:
WO 2,009,063,301

Inventor(s): BRUSSEE JOHANNES [NL]; IJZERMAN ADRIAAN PIETER [NL]; ALEWIJNSE ASTRID ELINE [NL]; PETERS STEPHAN LEONARD MARIA [NL]; BEUKERS MAR

Type of Offer: Sale



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