Hydroxyapatite and Bioglass-based Pellets, Production Process and Applications of Thereof

The present invention refers to hydroxyapatite and bioglass-based pellets of homogeneous size and spherical shape, whose interconnective porous structure, in the micrometer range, allows for an enhanced osteoconductivity and osteointegratioh, with specific application as a synthetic bone graft and to the respective production process. The production process is based on the pharmaceutical technology of extrusion and spheronization employing a porogenic agent and applying a sinterization stage. in the presence of a vitreous liquid phase, which reverts on behalf of a higher reproducibility, superior yield and greater production capacity. Therefore, the present invention is destined to the production of hydroxyapatite and bioglass-based pellets with applications. in osteoregenerative medicine, particularly in the fields of orthopaedic surgery, maxillofacial surgery, dental surgery, implantology and as tissue engineering scaffolds

Patents:
WO 2,010,021,559

Inventor(s): DOMINGOS DA SILVA SANTOS JOSE [PT]; FERREIRA DA SILVA LOPES MARIA [PT]; ALVES DA SILVA MARTA [PT]

Type of Offer: Sale



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