Nogo Receptor Binding Small Molecules to Promote Axonal Growth

The present invention provides a method for identifying compounds which modulate the interaction of Nogo and Nogo receptor (NgR). The present invention also provides compounds that modulate the interaction of Nogo and Nogo receptor (NgR), the use of such compounds and compositions in the treatment or amelioration of conditions diseases or disorders, such as spinal cord injury, traumatic brain injury, stroke, multiple sclerosis, ALS, Huntington's disease, Alzheimer's disease, Parkinson's disease, epilepsy, Schizophrenia or schizoaffective disorders.

Patents:
US 20,110,065,715

Inventor(s): STRITTMATTER STEPHEN M [US]; GUNTHER ERIK [US]

Type of Offer: Sale



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