Delivery of H2 Antagonists

The present invention provides improved systems and methods for the local delivery of H2 antagonists. The inventive methods include topical administration of an effective amount of a H2 antagonist encapsulated in liposomes. In certain embodiments, the H2 antagonist, for example, Cimetidine, is encapsulated into paucilamellar liposomes, such as NOVASOME TM microvesicles. Also provided are pharmaceutical compositions comprising liposome-encapsulated H2 antagonists. The methods and compositions of the present invention may be used to treat any disease state or condition where local administration of H2 antagonists is beneficial.

Patents:
US 20,110,135,716

Inventor(s): VAN DYKE THOMAS E [US]; HOLICK MICHAEL [US]; KANTARCI ALPDOGAN [US]; HASTURK HATICE [US]

Type of Offer: Licensing



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