Neuroprotective Compositions and Methods

This disclosure concerns novel methods for preventing or treating neurological or neurodegenerative diseases or disorders by using kombo butter acid enriched extracts derived from the seeds of African nutmeg, the main active compounds isolated from the extracts, namely sargaquinoic acid, sargachromenol, and sargahydroquinoic acid, or synthetic analogs or derivatives thereof, as neuroprotective agents. The methods for preparing the kombo butter or kombo butter acid extracts and the methods for isolating and purifying the active compounds and for preparing their acetylated derivatives are also described.

Patents:
WO 2,010,111,584

Inventor(s): SIMON JAMES E [US]; WU QING-LI [US]; DENG WENBIN [US]

Type of Offer: Licensing



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