Hydrogel-grafted Degradable Nerve Guides
The present invention is directed to the compositions and methods of preparing hydrogel-grafted nerve guides for peripheral nerve regeneration. Particularly, the present invention describes the nerve guides and methods for preparation of hydrogel-grafted nerve guides with encapsulated neurotrophic factors and a nanofiber mesh lining the inner surface of the guide. The present invention also provides methods for peripheral nerve repair using these hydrogel-grafted nerve guides.
HOKE AHMET [US]; LIM SHAWN HWEI-IN [US]; LIU XINGYU [US]; MAO HAI-QUAN [US]
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