Method, Kit Or Diagnostic for the Detection of Reagents which Induce Altered Contractility
A method of screening for compounds that enhance or depress contractile function, based on measuring the formation of heterodimers of contractile fibers (e.g. Tm and actin, myosin heavy and myosin light chains), for example through disulfide bond formation. Diagnostic and prognostic methods and kits are also provided.
MURRAY CHRISTOPHER I [US]; VAN EYK JENNIFER E [US]; PAOLOCCI NAZARENO [US]; GAO WEI DONG [US]; FOSTER DARREN BRIAN [US]
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