Methods for Heat Shock Protein Dependent Cancer Treatment

The present invention provides a method of treating an Hsp70 dependent cancer, including: providing at least one Hsp70 dependent cancer cell; contacting the at least one cell with a sub-effective concentration of a dihydropyrimidinone compound; and contacting the at least one cell with a sub-effective concentration of a proteasome inhibitor, wherein the sub-effective concentration of the dihydropyrimidinone compound and the sub-effective concentration of the proteasome inhibitor have a synergistic effect upon the at least one cell.

Attached files:


Patents:
WO 2,009,023,846

Inventor(s): BATUMAN OLCAY [US]; BRODSKY JEFFREY L [US]

Type of Offer: Licensing



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