Ngal-binding Siderophores and Use Thereof to Treat Iron Deficiency and Iron Overload

The invention provides compositions comprising a lipocalin, such as NGAL, and a mammalian siderophore that are useful as iron chelators and iron donors. The invention also provides mammalian siderophore compounds of Formula (I): The invention further provides, methods of treatment and methods of diagnosis.

Attached files:
WO 2010033847.jpg

Patents:
WO 2,010,033,847

Inventor(s): BARASCH JONATHAN [US]; DENG SHIXIAN [US]; BAO GUANHU [US]; LANDRY DONALD W [US]

Type of Offer: Licensing



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