Compensating for Atrioventricular Block Using a Nucleic Acid Encoding a Sodium Channel Or Gap Junction Protein
A method of increasing the velocity of AV conduction in a mammal that may be in heart block or at risk of heart block by causing, in an AV node and/or His bundle having less than normal conduction speed, the expression of a sodium channel or gap junction protein, such as the SkM-I channel, Cx43 or Cx32, so as to increase the velocity of conduction by the AV node.
COHEN IRA S [US]; BRINK PETER R [US]; ROSEN MICHAEL R [US]; ROBINSON RICHARD B [US]
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