Compounds and Methods for Inhibiting Serotonin Synthesis

Compounds having the structures below that are TPH1 inhibitors are provided: The compounds are useful for lowering serum serotonin levels in a patient in need thereof, e.g., to increase bone mass. In preferred embodiments, the patient is known to have, or to be at risk for, a low bone mass disease such as osteoporosis.

Patents:
WO 2,011,053,977

Inventor(s): LANDRY DONALD [US]; DENG SHI-XIAN [US]

Type of Offer: Licensing



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