Artificial Lectin Mimics and Uses Thereof
Lectins are important class of sugar-binding proteins involved in a variety of biological phenomena. In some aspects, the present invention relates to the process of selection and application of high-fidelity artificial lectin mimics in the construction of microarray devices capable of precise, rapid and inexpensive analysis of glycoproteins, pathogen detection, and diagnosis of various disease states. In some aspects, the invention also relates to the use of identified binding peptides on solid support or free in solution in cell sorting, affinity purification, and other applications where natural lectins are traditionally used.
SVAROVSKY SERGEI [US]; BOLTZ KATHRYN [US]; JOHNSTON STEPHEN ALBERT [US]; GONZALEZ-MOA MARIA [ES]
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