Delivery System for Heparin-Binding Growth Factors
A device comprising a scaffold coated with a protein having at least 83% identity to the amino acid sequence of the core protein of domain I of a mammalian perlecan, wherein at least one glycosaminoglycan is attached to the protein is described. The device may be used in vitro or in vivo to induce replication and/or differentiation of connective tissue cells and to repair tissue.
CARSON DANIEL D [US]; FARACH-CARSON MARY C [US]; FRENCH MARGARET [US]; GOMES RONALD [US]
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