Prenylated Bisphosphonates As Anti-tuberculosis Agents

The invention provides methods to treat a mycobacterium infection and methods to inhibit mycobacterial polyprenyl pyrophosphate synthesis with a compound of formula I. The invention also provides novel compounds of formula I as well as salts and prodrugs thereof.

Attached files:
WO 2010108190.jpg

Patents:
WO 2,010,108,190

Inventor(s): WIEMER DAVID F [US]; BARNEY ROCKY J [US]; HOHL RAYMOND J [US]

Type of Offer: Licensing



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