Vaccine Composition Comprising 5'-cap Modified RNA
The present invention relates to modification of RNA with 5 '-cap analogs in order to improve the stability and increase the expression of said RNA, in particular in immature antigen presenting cells. The present invention provides a vaccine composition comprising said stabilized RNA, immature antigen presenting cells comprising said stabilized RNA, and methods for stimulating and/or activating immune effector cells and for inducing an immune response in an individual using said stabilized RNA.
Patents:WO 2,011,015,347 [
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Inventor(s):
SAHIN UGUR [DE]; KUHN ANDREAS [DE]; DARZYNKIEWICZ EDWARD [PL]; JEMIELITY JACEK [PL]; KOWALSKA JOANNA [PL]
Type of Offer:
Sale
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