Vaccine Composition Comprising 5'-cap Modified RNA

The present invention relates to modification of RNA with 5 '-cap analogs in order to improve the stability and increase the expression of said RNA, in particular in immature antigen presenting cells. The present invention provides a vaccine composition comprising said stabilized RNA, immature antigen presenting cells comprising said stabilized RNA, and methods for stimulating and/or activating immune effector cells and for inducing an immune response in an individual using said stabilized RNA.

Patents:
WO 2,011,015,347   [MORE INFO]

Inventor(s): SAHIN UGUR [DE]; KUHN ANDREAS [DE]; DARZYNKIEWICZ EDWARD [PL]; JEMIELITY JACEK [PL]; KOWALSKA JOANNA [PL]

Type of Offer: Sale



« More Medical Patents

---