Use of Hat Inhibitors and TMPRSS2 Inhibitors As Medicaments

The invention relates to the use of inhibitors of the general formula (I) where R1 is a substituent, P3 is a mono- or polysubstituted or unsubstituted, natural or unnatural a-amino acid or a-imino acid in the D configuration, P2 is a mono- or polysubstituted or unsubstituted, natural or unnatural a-amino acid or a-imino acid in the L configuration, and P1 is an arginine mimetic, the basic group of which may optionally also be present as a prodrug, for inhibition of the serine proteases HAT and TMPRSS2 for treatment of viral infections, for treatment of inflammatory respiratory pathway disorders or for treatment of tumors and prevention of metastases.

Attached files:


Patents:
WO 2,010,149,459   [MORE INFO]

Inventor(s): STEINMETZER TORSTEN [DE]; SIELAFF FRANK [DE]; GARTEN WOLFGANG [DE]; BOETTCHER EVA [DE]; FREUER CATHARINA [DE]; MATROSOVICH MIKHA

Type of Offer: Sale



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