N-terminally Modified Tetrapeptide Derivatives Having a C-terminal Arginine Mimetic

The invention relates to multi-base, N-terminally modified tetrapeptide mimetics having a C-terminal P1 arginine mimetic, to a method for producing the same and to the use thereof in the therapy and prophylaxis of diseases that are caused by bacterial pathogens or viruses, and in the therapy and prophylaxis of diabetes, arteriosclerosis, cancer, Alzheimer's or the development of overweight, and to the use of the compounds as inhibitors of proprotein convertases which cleave downstream of basic P1 residues, especially for inhibiting furin protease.

Patents:
WO 2,010,048,941

Inventor(s): STEINMETZER TORSTEN [DE]; BECKER GERO [DE]; GARTEN WOLFGANG [DE]

Type of Offer: Sale



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