Inhibition of Cell Proliferation
Compounds of formula (I) and (II) are provided as modulators of Rb:Raf-1 interactions which are potent, selective disruptors of Rb:Raf-1 binding. Therapeutic methods of using the compounds, for example for treating or ameliorating a cell proliferation disorder such as cancer, are provided.
SEBTI SAID M [US]; CHELLAPPAN SRIKUMAR [US]; LAWRENCE NICHOLAS JAMES [US]
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