Acylsulfonamides and Processes for Producing the Same
The present disclosure relates to acylsulfonamides and processes for their preparation. The processes involve a target-guided synthesis approach, whereby a thioacid and a sulfonyl azide are reacted in the presence of a biological target protein, a Bcl-2 family protein, to form the acylsulfonamide.
WO 8,524,947 issued 2013-09-03 [MORE INFO
MANETSCH ROMAN [US]; WANG HONG-GANG [US]; HU XIANDONG [US]; KULKAMI SAMEER [US]; SUN JIAZHI G [US]
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