Inhibiting Eph B-3 Kinase
EphB3 kinase inhibitor compounds, including certain pyrazolo[1,5-a]pyridine and imidazo[1,2-a]pyridine compounds, inhibit EphB3 kinase. The EphB3 kinase inhibitor compounds can have greater potency for the inhibition of EphB3 kinase than general kinase inhibitors. Pharmaceutical compositions, such as neuroprotective agents, comprising the EphB3 kinase inhibitor compounds are also provided. The EphB3 kinase inhibitor compounds and pharmaceutical compositions are useful, for example, to provide neuroprotection and/or repair of neuronal tissue damaged during an ischemic event, such as a stroke.
Attached files:Patents:WO 2,010,117,787 [
MORE INFO]
Inventor(s):
QIAO LIXIN [US]; GLICKSMAN MARCIE [US]; GAINER THOMAS [US]; LO DONALD C [US]; STEIN ROSS L [US]; CHOI SUNGWOON [US]; CUNY GREGOR
Type of Offer:
Licensing
« More Pharmaceutical Patents