Inhibiting Smad signaling promotes neuron regeneration

Regeneration of a lesioned CNS axon of a mature neuron, determined to be subject to regeneration inhibition by Smad2/3 signaling, is promoted by contacting the neuron with an inhibitor of Smad2/3 signaling sufficient to promote regeneration of the axon.

US 20,090,181,420

Inventor(s): HE ZHIGANG [US]; WANG FAN [US]

Type of Offer: Licensing

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