Compositions and Methods for Inhibiting Sphingosine Kinase
Amidine analogs that can inhibit the activity of sphingosine kinase 1 and sphingosine kinase 2 (SphK1 & SphK2) are provided. The compounds can prevent angiogenesis in tumor cells.
LYNCH KEVIN R [US]; MACDONALD TIMOTHY L [US]; KHAREL YUGESH [US]; MATHEWS THOMAS P [US]; WAMHOFF BRIAN R [US]
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